“a decreasing trend”

Discussion In this study, a decreasing trend in the podocyte marker protein nephrin in db/db mice was observed; although, there was no significant difference in protein expression and localization compared with db/m control mice.

The serum transaminases peaked at day 3 and showed a decreasing trend by day 5.

Shannon index values demonstrated an increasing trend of α diversity in breast-fed group and a decreasing trend in formula B-fed group over time, but the differences were not significant neither in breast-fed group (40 days versus 3 m p = 0.7627, 40 days versus 6 m p = 0.1483, 3 m versus 6 m p = 0.0827) nor in formula B-fed group (40 days versus 3 m p = 0.0276 > corrected p value 0.0167; 3 m versus 6 m p = 0.3557).

The blue edge position moved to the short wave direction first and then to the long side direction, while the blue edge slope generally shows a decreasing trend.

The use of 3D models reduced flap harvest times with statistical significance for bilateral DIEP and MS-TRAM flaps, while there was a decreasing trend but no significant difference in flap harvest times for unilateral flaps.

Our study also showed that the incidence and mortality in esophageal cancer were highest in men and in the 70+ years age group, and they presented a decreasing trend in most regions, but the 15‐49 years age groups in Australasia, Caribbean, and Oceania and the 70+ years age group in High‐Income North America, Oceania and high‐SDI regions presented an increasing trend.

Hospitalisation for sepsis showed a decreasing trend between 2001 and 2007 in men (APC −10.5 [95% CI −15.8, −4.9]) and between 2001 and 2006 in women (APC −12.6 [95% CI −20.1, −4.3]), followed by increases in rates over the remaining time period in both men (APC 2.7 [95% 0.7, 4.7]) and women (APC 4.0 [95% CI 0.2, 8.0]) (Table 1 , Fig. 1h ).

This is of particular relevance since the utilization of neoadjuvant therapy increased over the study period (from 9.9% to 24.0% [data not shown]) concomitant with a decreasing trend of operative intervention over the same period.

Both Notch1 and Hes1 showed a decreasing trend in mRNA expression over time post-resection in both the control and Fli-06 groups, while Vegf showed an increasing trend in mRNA expression.

LNK showed a decreasing trend with the elevation of BMI and then an increasing trend after a BMI level of 24-28 kg/m 2 ( Figure 1A ).

It was found that at the selected time points after I/R injury, Opa1 protein expression also exhibited a decreasing trend, which was statistically significant only 7 days after I/R ( Fig. 4A ).

Although there was a significant decrease only in fungal PLFAs and G− bacterial PLFAs rather than G+ bacterial PLFAs, we noticed a decreasing trend of G+ bacteria in the urban forests.

Volume and total sperm count showed increasing trend while concentration showed a decreasing trend with an increase in age.

pachyderma spans from 0.4‰ to -0.3‰ (VPDB) and is dominated by multi-decadal variability with a decreasing trend especially since the 1940s/1950s ( Fig 3B ).

It is shown that (1) the spatial distribution of the urbanization level of the urban agglomeration in Central Yunnan has significant regional differences, showing a decreasing trend from the urbanized area to the surrounding areas.

As would be expected during Bet v 1-specific immunotherapy resulting in an immune shift away from the allergenic Th2 responses toward Th1, the ratios of Bet v 1-specific IgG1 to IgG2a ( Figure 4c ), and total IgE to Bet v 1-specific IgG2a ( Figure 4e ) showed a decreasing trend in the CMPG11250 group, and to a lesser extent in the L. rhamnosus GR-1 pretreatment group.

The OEF and CMRO 2 values in the ischemic core showed a decreasing trend as the time between symptom onset and MRI examination increased ( Figures 2 , 3 , respectively), while the CBF and ADC values showed a slight increasing trend ( Figures 4 , 5 , respectively).

In contrary, since 1970, a decreasing trend in the BMI of Japanese women was noticed ( 6 ) , and meanwhile accompanied by almost a double-fold increase in the rate of low birth weight in the country since then ( 7 ) .

Although with a decreasing trend, GCs still represent an important percentage of total deaths in the country, influencing the quality of mortality information.

An increased serum folate level was also related to a decreasing trend of EPL and ESCC risks when p16 or p53 methylation occurred.

Since smoothing the data revealed a decreasing trend, four of the time-series models (Linear, Quadratic, Exponential and Autoregressive forecasting) were tested to find out which model best explained the trend.

Thirdly, the well-being of the elderly shows a decreasing trend with age.

Likewise, we observed a good correlation between depth or soil age and alpha diversity indices, as all diversity estimates showed a decreasing trend with increasing depth/age (Fig. 3 ).

The same occurred with D-dimer, an independent predictor of hospital death in patients with COVID-19 26 , that reflects a pro-coagulant state and increased thrombotic risk associated with severe disease in COVID-19 27 , and which only showed a decreasing trend in patients responding to TCZ.

The cell survival rate demonstrated a decreasing trend, after an initial slight increase, with increasing curcumin concentration.