Barely Significant
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“a decreasing trend”

47,181 sentences · 47,181 papers · 78,848 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Significantly, a decreasing trend in resistance levels was observed over the study period for most antibiotics, including cefoxitin (from 19.5 to 9.2%), aztreonam (from 42.2 to 30.2%), amoxicillin/clavulanic acid (from 26.9 to 19.5%), piperacillin/tazobactam (from 12.3 to 7%), gentamicin (44–35.3%), ciprofloxacin (65.7–58.1%), trimethoprim/sulfamethoxazole (60.8–52.4%) and cephalosporins (Table 1 ).
showed (i) a decreasing trend of mtDNA‐CN with an increasing number of APOE4 alleles carried by AD patients; (ii) increased mtDNA‐CN in AD patients treated with acetylcholinesterase inhibitors compared to drug‐naïve patients [ 65 ]. mtDNA heteroplasmy, damage and methylation The studies addressing mtDNA heteroplasmy in AD showed contrasting results.
The end products of glycolysis, pyruvate and lactate, as well as some metabolites related to the TCA cycle, showed a decreasing trend as oxidative stress levels increased, which is consistent with the relating literature. 47,48 Correspondingly, the intermediate metabolites exhibited an upward trend, 49 suggesting that the increase in oxidative stress may have a significant and irreversible impact on the activity of downstream metabolic enzymes.
Further, KEGG pathway analysis of the above target genes showed that the target genes of miR-185-5p were widely involved in the p53 signaling pathway, ErbB signaling pathway, and GnRH signaling pathway ( Figure 5E ). Discussion The results of this study showed that compared with the control group, the expression of GUSBP11 and miR-185-5p in gingival crevicular fluid in CP group showed an increasing trend and a decreasing trend, respectively.
Subsequent PCR and immunohistochemistry analyses of HIOSRGs demonstrated an increasing trend in ABCG2 and ALDH18A1, and a decreasing trend in CYP1A2 and HDAC3 in the intestinal tissue of IIRI mice compared to Sham group mice ( Figure 7C-N ) ( Figure 8A-D ), thereby affirming the reliability of HIOSRGs through in vivo experiments.