Table 5 shows that when the original model amino acid frequencies were randomly perturbed, there was a definite trend among all of the model selection measures to select the corresponding '+F' version of the particular model over the original models.
Padilla et al showed that although there was a definite trend toward decreasing MCD and MCA with increasing age up to sixth decade of life, but a reverse trend was noted at 61 and above [ 4 ].
A definite trend in the data indicates that this effect is seen to a somewhat lesser extent at concentrations of chloroform as low as 400 mg/L.
A definite trend toward improvement was observed in a phase II study in both joint structure and symptoms in patients with primary knee OA treated with risedronate.
One month after spraying, there was no appreciable change in IgG results but significant J-WS specific IgE titers were demonstrated in 5 of 16 skin- test-positive high-exposure workers. Although there was not a correlation between skin test positivity and the cut-off level of J-WS-specific IgE [? mean + 3 SD (0.18) of a pool of 14 nonexposed urban control sera], there was a definite trend to rising specific IgE anti- body titers 1 month after exposure.
No significant correlation was observed between overexpression of c-erbB2 mRNA and early disease recurrence in our group of patients, although there was a definite trend towards poorer prognosis.
However, the role of REC status as an indicator of a 46 likely response to chemotherapy in ad- vanced breast cancer patients is disputed (Lippman et al., 1978; Kiang et al., 1978). In this studv there was no statistical corre- lation between of subunit levels and the presence or absence of hormone receptors, either individuallv or in combination though there was a definite trend towards higher a levels in those pre- and postmeno- pausal patients who were REC- and RPC-.
In the experiments described here fibroadenomas and adeinomas showed a definite trend to develop in older animals in association with well developed lobules w-hile c(arcinomas arose generally in younger animals from ducts and end-buds, i.e tumours arose at a time before all the end-bud regions became converted into (luctules and lobules.
The experiments do establish beyond doubt that some examples of this particular type of sarcoma are true malignant neoplasms in behaviour as well as in appearance. From the present study there is little evidence that massage or repeated sub- total ablation of a tumour affects appreciably the incidence of metastases. Possibly these effects are more readily demonstrated with tumours more prone to metastasize; a definite trend might have been established with the present group of tumours had more animals been used.
ty." The reasons for expressing the entire 15 pre-inoculation blood cell values as a single value are as follows: first, the technical inaccuracy of the mean of any particular blood cell value may be great; second, a single such inaccuracy might Since the paper upon distributions (2) was published, a definite trend in cer- tain classes of cells has occurred, necessitating slight changes in the modal values for total white cells, eosinophiles, and lymphocytes.
There was a definite trend for the rabbits with the greatest number of arterial lesions to have shown the greatest rise in sedimentation rate in the group receiving whole serum, an observation which we have noted previously 588 CARDIOVASCULAR AND RENAL LESIONS PRODUCED BY SERUM (10).
6 }23/26 3is} 0/4 3/15 0/6 +P, poliomyelitis virus isolated, -t-C, C virus isolated, -P, polio virus not recovered, -C, C virus not recovered, nd P, no test made for poliomyelitis virus. 16/20 means that of 20 patients tested, the sera of 16 showed increases in antibodies. sera (see Table XIV) show a definite trend, which was reproducible on sera collected from the same individuals 1 month and again 3 to 4 months later.
There was also a definite trend for material to become more alcohol-soluble with time, e.g., in the 16-24 hr period as com- pared to the 0-4 hr period.
However, in ER+ breast cancers a definite trend toward significance between SBEM protein levels and disease outcome of patients was observed, suggesting that SBEM may be associated with worse survival and shorter time to progression in this specific subgroup.
However, our observation seems to be similar to results reported by Rothenberg et al (2005) , in which they were not able to confirm a correlation between the inhibition of Akt and MAPK and response to an EGFR TKI (gefitinib) in colorectal cancer, but suggested a definite trend for inhibition of the EGFR-driven activation of downstream regulators in patients achieving a longer progression-free survival.
On further analysis grade I tumours, lymph node-negative tumours, patients with <3 positive lymph nodes and ER/PR positive tumours showed a definite trend to have only unmethylated alleles i.e. active p16.
These values are lower compared to results obtained for radiation ( Kadhim et al , 1997 ) but they show a definite trend towards genomic instability.
Although the results on malaria deaths have to be judged with caution because of under-reporting, they give, nevertheless, a definite trend of lower death rates attributable to fever in the study area in comparison to control area.
The change in the scalar coupling on inclusion of explicit water molecules does not follow a definite trend, which is expected since the solvent molecules are directly interacting with the solute and thus the change in electronic configuration is complex.
However, changes in associations between chromosomal arrangements and chromosomal sites do not follow a definite trend.
ne (0) 2 1 0 0 1 1 3 2 0 0 20 Dense (2) 5 0 13 9 15 11 9 4 15* 13 Faint (1) 9 16 5 8 2 6 8 12 3 2 None (0) 4 1 0 0 1 0 1 1 0 2 30 Dense (2) 4 2 13 10 16* 10 10 4 20 19 Faint (1) 15 20 10 12 7 13 12 18 2 4 None (0) 4 2 0 2 0 1 1 2 1 1 * = p <.05 ** = p <.01 Note: At all sites there is a definite trend toward denser opacification with iodamide than with Renografin.
J. Physiol., 1929, 90, 247. 94 AUGUST KROGH Also in his zoophysiological work a definite trend can be followed through the years.
Local health departments have recognized the health educator as an indispensable member of the public health team, and there is a definite trend toward the "five-piece" unit.
The observed correlation 2900 must be, therefore, regarded as signifi- 2800' cant, indicating a definite trend toward 2700- infants of greater weight in patients with 2600- larger pelves.
Although the participation scores appear to exhibit a definite trend with exposure, Group 1 having the highest participation and Group 4 the lowest, absolute differences between the rates of the exposure categories are small.