Barely Significant
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“a numerical trend”

1,013 sentences · 1,013 papers · 1,817 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

None of these differences were significant; there was a numerical trend to a slightly larger loss (by 1.2 units in the CIDD) during deflazacort treatment compared to placebo (Figure 3 a; change between start and end of pooled crossover periods: deflazacort: d = −2.24; standard deviation (SD) = 3.0; placebo: d = −1.00, SD = 2.2; mixed model result (ITT): p(treatment) = 0.1558; 95% confidence interval [−3.01; 0.52] in disfavor of deflazacort; non-parametric analysis (PP): p = 0.4375).
Post hoc analyses by patient subgroups At week 28, patients stratified by prior and non-prior anti-TNF use showed similar ACR20, ACR50 and ACR70 response rates in the placebo → CZP and CZP → CZP groups, although there was a numerical trend for slightly higher response rates in the anti-TNF naïve patients (Fig. 3a ).
ICU-ROX demonstrated substantial subgroup variation: patients with hypoxic-ischemic encephalopathy (HIE) showed a numerical trend favoring conservative oxygen therapy (180-day mortality 43% vs. 59%, relative risk=0.73), whereas patients with sepsis experienced lower mortality with liberal oxygen therapy (180-day mortality 33.1% vs . 36.2%).