“a numerical trend”

Although LVMI was not statistically significant, there was a numerical trend, which is consistent with the results of unmatched analysis ( Supplementary Table S5 ).

ISR incidence decreased over time regardless of BMI group or dosing regimen, with a numerical trend toward fewer ISRs in the higher BMI group overall ( Figure 1 ).

Over the 3 phases, there was a numerical trend towards a slightly better accuracy from 23.6% to 28.0%—which was also observed within the two subgroups (residents and oncologists)—which however lacked statistical significance in all subgroups (see table 2 ).

We evaluated age- and sex-related differences in chronic cough, finding a significantly higher prevalence of chronic cough among females and a numerical trend of increasing prevalence of cough in the prior 12 months with older age.

There was no significant difference in rate of recurrent ischemic events at 90 days for patients who were DWI positive versus negative, though there was a numerical trend toward higher recurrence rate with DWI positivity.

21 , 24 Although there was a numerical trend in PFS favoring ibrutinib + CIT, the study was not adequately powered to allow for a formal statistical comparison, given the small number of patients with MZL.

They found a numerical trend in the opposite direction, i.e., the processing advantage for unpredictable words in constraining sentences compared to neutral sentences.

However, a numerical trend was observed for OS in favor of Isa‐Kd compared with Dara‐Rd after matching adjustment. 3.4.

We also observed enrichment of the peroxisome-proliferator-activated receptor alpha (PPARα) signaling pathway, along with a numerical trend of decreased AT levels of OEA and PEA, which are known to activate PPARα 68 .

Yet, owing to the small sample size solely a numerical trend and no statistical significance of the benefit of PMRT on the oncologic outcome of patients following a therapeutic mastectomy with remaining fibroglandular breast tissue could be shown.

The main effect of text justification was not significant though there was a numerical trend suggesting that return-sweep landing position was closer to the left margin of a new line in the left-justified condition than the fully-justified condition.

Although the differences in other ocular symptoms upon instillation were not statistically significant, there was a numerical trend in favor of PFB 0.01% gel for stinging, tearing, and foreign body sensation.

There was a numerical trend towards a higher MACE rate with the monotherapy, which was predominantly driven by stroke events.

Yet, in our series, once PSM was adjusted by comorbidities, including age, sex, or pulmonary disease, the differences in mechanical ventilation disappeared although a numerical trend of non-apical forms was maintained.

There was also a numerical trend evident for the three groups independently (Table 2 ) with 5.13% versus 2.38% for severe CRS (relative risk 1.679; 95% CI 0.947–2.583), 5.77% versus 4.28% for severe CRS and NT (relative risk 1.247; 95% CI 0.6874–2.004), and 9.62% versus 5.94% for severe NT (relative risk 1.428; 95% CI 0.9038–2.085) although not reaching statistical significance.

There was a numerical trend toward a smaller change in monthly migraine headache days after treatment discontinuation as the treatment duration increased.

8 In another phase 3 study ( NCT00337103 ), eribulin-treated patients did not have a significant improvement in OS as compared to patients treated with capecitabine in the first, second, or third line of chemotherapy in the metastatic setting, although a numerical trend favoring eribulin was demonstrated. 9 Interestingly, in a subsequent pooled analysis of both of these trials, eribulin was seen to have a significant improvement in OS, as compared to the control arm.

Although statistically significant prognostic comparisons were limited by the small sample size in our internal cohort and MYC status was only evaluable at the time of recurrence, there did appear to be a numerical trend towards worse median survival with MYC amplification, as well as higher rates of recurrence, despite the majority of patients ultimately receiving immunotherapy in addition to chemoradiotherapy, conforming with previous observations 36 .

In female patients assigned to mGPS category 1 or 2, a numerical trend towards longer OS was also observed in Arm A compared to Arm B, however, with statistical testing not revealing a significant survival difference between treatment arms (24.6 versus 16.7 months; P = 0.15) ( Supplementary Table S1 , available at https://doi.org/10.1016/j.esmoop.2024.103374 , Figure 4 A and B).

This long-term, prospective, randomised, head-to-head trial demonstrated a numerical trend for increased risk of MACE and VTE (only the 10 mg dose), among other serious adverse events, for the JAK inhibitor tofacitinib compared with TNF inhibitor therapy in a population enriched for CV risk (patients who were aged ≥50 years with at least one CV risk factor). 16 The increased relative ris

15 Final OS results show a numerical trend favoring ipatasertib–paclitaxel (median OS 23.1 vs 18.4 months in ipatasertib vs placebo arm, stratified HR 0.62 [95% CI, 0.37-1.05]). 33 However, the Phase III IPATunity130 cohort A failed to show PFS benefit from the addition of ipatasertib to paclitaxel in patients with mTNBC harboring PIK3CA/AK

Nonetheless, those patients who had ≥12 months of PFS during prior palbociclib‐based therapy only had a numerical trend towards PFS improvement compared with those patients who had less than 12 months of PFS during prior palbociclib‐based therapy (median PFS: 7.0 vs. 5.0 months, log‐rank p = 0.931).

Furthermore, a numerical trend toward higher chronic kidney disease in the urgent group was evident.

A numerical trend favoring birtamimab in the primary composite end point for the overall population was observed and was hypothesized to be driven by a treatment effect in the most advanced patients (Mayo stage IV).

While a numerical trend in favoring prolonged ET for patients with a higher CTS5 was found, a significantly predictive value for the score could not be confirmed.