Yet, in our series, once PSM was adjusted by comorbidities, including age, sex, or pulmonary disease, the differences in mechanical ventilation disappeared although a numerical trend of non-apical forms was maintained.
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There is a numerical trend towards a younger age (72 years vs. 75 years) and a larger portion of male patients (54% vs. 41%) in the Danish cohort.
There was also a numerical trend evident for the three groups independently (Table 2 ) with 5.13% versus 2.38% for severe CRS (relative risk 1.679; 95% CI 0.947–2.583), 5.77% versus 4.28% for severe CRS and NT (relative risk 1.247; 95% CI 0.6874–2.004), and 9.62% versus 5.94% for severe NT (relative risk 1.428; 95% CI 0.9038–2.085) although not reaching statistical significance.
There was a numerical trend toward a smaller change in monthly migraine headache days after treatment discontinuation as the treatment duration increased.
LB2: 92.5%), (3) LB ablation showed an acceptable safety profile, with an overall complication rate of 8.9% and a numerical trend to lower complication rates with LB2 (LB1: 10.1% vs.
Association Between Weight Reduction and PROs Although statistical tests were not conducted, results of these additional exploratory post hoc analyses showed that there was a numerical trend towards improved SF-36v2 Physical and Mental Component Summary scores in participants treated with tirzepatide achieving greater percentage reductions in weight, with participants achieving ≥ 15% weight reduction reporting the greatest improvements in component summary scores (after adjustment for baseline PRO scores) (Fig. 5 a).
There was a numerical trend that cfABCB1 tx levels at primary diagnosis were elevated in platinum resistant patients (ED = 304 mRNA copies/20 μl serum).
Although the difference in the risk scores between responders and non-responders in the Zhao GBM anti-PD1 cohort was not statistically significant, there was indeed a numerical trend showing higher scores in non-responders compared to responders ( Fig. 5 F).
For the subset of patients where the method's assessment is in disagreement with the final IRC response, we observe a numerical trend where the OS survival rates of patients assessed as CMR by the model and non-CMR by the final IRC response are numerically better than the survival rates of non-CMR patients by the model and CMR by the final IRC response (Data Supplement, Fig S12).
There was a numerical trend in favor of the combination therapy with palbociclib and AI for rwPFS, but not for OS 36 .
8 In another phase 3 study ( NCT00337103 ), eribulin-treated patients did not have a significant improvement in OS as compared to patients treated with capecitabine in the first, second, or third line of chemotherapy in the metastatic setting, although a numerical trend favoring eribulin was demonstrated. 9 Interestingly, in a subsequent pooled analysis of both of these trials, eribulin was seen to have a significant improvement in OS, as compared to the control arm.
A further correlation also demonstrated this trend in relation to fecal calprotectin as an objective measure of IBD activity; however, this was only observed as a numerical trend without reaching statistical significance.
Although statistically significant prognostic comparisons were limited by the small sample size in our internal cohort and MYC status was only evaluable at the time of recurrence, there did appear to be a numerical trend towards worse median survival with MYC amplification, as well as higher rates of recurrence, despite the majority of patients ultimately receiving immunotherapy in addition to chemoradiotherapy, conforming with previous observations 36 .
DRSS improvement Rates of at least 2-step DRSS improvement were largely consistent across treatment arms and between the YOSEMITE Japan subgroup and the pooled YOSEMITE/RHINE cohort at weeks 52 and 96, although there was a numerical trend for higher proportions in the faricimab arms versus the aflibercept arm in the YOSEMITE Japan subgroup (Fig. 5 ).
In female patients assigned to mGPS category 1 or 2, a numerical trend towards longer OS was also observed in Arm A compared to Arm B, however, with statistical testing not revealing a significant survival difference between treatment arms (24.6 versus 16.7 months; P = 0.15) ( Supplementary Table S1 , available at https://doi.org/10.1016/j.esmoop.2024.103374 , Figure 4 A and B).
Although there was a numerical trend for an increasing incidence of all three outcomes with the numerically highest rate occurring for the FIB-4 highest tertile, the differences between tertiles were not statistically significant.
An analysis from the year 2000 did not show a statistically significant connection between preoperative ECG with bundle branch block (BBB) and mortality, but there was a numerical trend in the LBBB group [ 7 ].
Final overall survival (OS) results from LOTUS showed a numerical trend favoring ipatasertib-containing therapy in both the intent-to-treat (ITT) and the biomarker-selected populations, with median OS exceeding 2 years ( 11 ).
Our trial revealed significant NLR improvement in patients treated with Ayurveda plus standard of care (SOC) compared to SOC alone at 14 days, with a numerical trend continuing through 28 days.
This long-term, prospective, randomised, head-to-head trial demonstrated a numerical trend for increased risk of MACE and VTE (only the 10 mg dose), among other serious adverse events, for the JAK inhibitor tofacitinib compared with TNF inhibitor therapy in a population enriched for CV risk (patients who were aged ≥50 years with at least one CV risk factor). 16 The increased relative ris
The FFT transformation converts the maximum frequency amplitude from its peak value to the maximum magnitude, producing a numerical trend similar to the maximum magnitude.
4 ) and a numerical trend in GFAP immunostaining (Fig. 4 and representative images in Supplementary File 8 ).
It is also of interest that presence of SE alleles was significantly associated with arthritis progression, whereas exposure to cigarette smoking was not, although smoking showed a numerical trend for association with disease progression.
15 Final OS results show a numerical trend favoring ipatasertib–paclitaxel (median OS 23.1 vs 18.4 months in ipatasertib vs placebo arm, stratified HR 0.62 [95% CI, 0.37-1.05]). 33 However, the Phase III IPATunity130 cohort A failed to show PFS benefit from the addition of ipatasertib to paclitaxel in patients with mTNBC harboring PIK3CA/AK
Nonetheless, those patients who had ≥12 months of PFS during prior palbociclib‐based therapy only had a numerical trend towards PFS improvement compared with those patients who had less than 12 months of PFS during prior palbociclib‐based therapy (median PFS: 7.0 vs. 5.0 months, log‐rank p = 0.931).