“a significant trend”

There was a significant trend for PD patients with CI to score lower in the domains of memory ( p = 0.00) and verbal fluency ( p = 0.04, shown in Table 5 ).

While the remaining 533 genes were induced in both cell lines, there was a significant trend toward RBM12-dependent hyperactivation ( p < 2.2 × 10 −16 by Wilcoxon signed rank test).

There was a significant trend of positive correlation between the risk score and the angiogenesis activity score (R = 0.32, p = 9.5e−13) (Fig. 7 J).

In total, we found a significant trend of gene number decrease in these independent mangrove clades ( Fig. 2 ; Wilcoxon signed-rank test; P = 1.04 × 10 −7 ).

Furthermore, a significant trend toward worse survival was found in the high-risk group ( p = 1.495 × 10 − 7 ).

To assess this possibility, we compared delta divergence from the consensus between neighboring ERVs (|neighbor_1_div—neighbor_2_div|) in ERV hotspots to other regions of the genome and report a significant trend in the opposite direction (Mann Whitney U, P = 3.317e−06), suggesting that SD is not the primary contributing mechanism to ERV hotspot formation.

In Cox regression, patients with multihit abnormalities had a 2.89-fold increased risk of death compared with those with wild-type TP53 (95% CI, 1.88-4.43), and those with single-hit abnormalities had a 1.63-fold increased risk of death (95% CI, 0.91-2.91) compared with those with wild-type TP53 ( Figure 2 D), with a significant trend in the HR as the number of TP53 abnormalities increased (likelihood ratio test, P = 5.42 × 10 −5 ).

In model 1, the ORs and 95 % (CIs) were 1.38 (1.02, 1.85), 1.73 (1.31, 2.27), and 2.93 (2.29, 3.76), respectively, with a significant trend (p < 0.0001).

There was a significant trend between CO level and MAE (p < 0.0001, Fig. 3 ).

Result Compared to the control group, FDM guinea pigs exhibited a significant trend towards myopia, along with significantly elevated concentrations of LPS and VIP ( p < 0.0001).

The serum IL1α levels were similar for both groups when the comparison was performed using a Tukey’s test ( p = 0.778); however, the linear test for trend indicated a significant trend ( p = 0.0001).

Remarkably, we found a significant trend of reduced N expression from BA.2 to XBB.1.5 in mice of all three age groups, including weanling mice (−R = 0.79, p < 0.0001), adult mice (−R = 0.73, p < 0.0001), and aged mice (−R = 0.73, p < 0.0001) ( Fig. 6 d).

4 C), there was a significant trend in the bias (linear regression: y = −0.574 x + 0.305, F = 29.65, DFn = 1, DFd = 72, P < 0.0001).

NAbs targeting the V3, CD4bs, and MPER demonstrated a significant trend in increasing order of median IC 50 s (p = 0.0001, 0.0135, and 0.0249, respectively) and decreasing order of median breadth (p = 0.0001, 0.0598, and 0.0098, respectively) over time.

A significant trend in the reduction of implantation of mechanical vs. biological prostheses was observed during the study period ( p < 0.0001).

3 D and E ), a significant trend of decrease was found (posttest for trend, κ ̄ , **** P < 0.0001; κ ̄ , *** P = 0.0005).

Comparison of the staining patterns among patients revealed a significant trend towards increased frequency of DFS pattern (ANA associated diseases 10.4%, JIA 21.7% and nonrheumatic conditions 34.8%, p < 0.0001) and decreased frequency of homogenous staining (ANA associated diseases 34.3%, JIA 26.7% and nonrheumatic conditions 8.9%, p < 0.0001) in nonrheumatic conditions.

We observed a significant trend before 2014 (slope = 1.47% increase in attachment rate per year, p < 0.0001), which flattened after 2014 (slope = 0.13%, p = 0.16).

However, mixed effects modelling revealed a significant trend for increasing LG at each timepoint (R2=.2, p<0.0001, PMA fixed effect, random intercept per infant).

This analysis revealed an over time decrease in the mean dissimilarity, which was significant between the day of discharge with the 2-month ( P < 0.001) and 4-month samples ( P < 0.0001), and a significant trend over time ( P < 0.0001).

Another type of interest is emm 12, which did not demonstrate a significant trend from 2018 to 2022; however, emm 12 decreased significantly from 4.5% (n=145) in 2018 to 1.0% (n=22) in 2021 ( p <0.0001), before significantly rising back up to 5.8% (n=151) in 2022 ( p <0.0001).

Again, females showed the worst results on the IES-R, with a significant trend across the scale’s severity levels (p<0.0001).

A significant trend toward a decrease in the number of skin lesions was observed (p<0.0001).

The exposure rate of the study population varied from 23.6% to 28.0%, and there was a significant trend toward increased exposure rate over time ( p < 0.0001).

When compared to healthy people of the same age, the proportion of peripheral immune T cells in tumor patients in the young, middle-aged, and elderly groups showed a significant trend of decline (P <0.0001), and the proportion of T cells in the tumor group gradually decreased with age (young 48.12%, middle-aged 46.09%, and elderly group 43.16%) ( Fig. 3 A ).