“a significant trend”

Concentration of ctDNA was significantly different between stages of disease [ H (3) = 15.307, p = 0.002], with a significant trend of increasing ctDNA concentration associated with more advanced disease at diagnosis defined by NCCN clinical stage ( J = 1103.5, z = 3.737, p < 0.001, r = 0.46) (Fig. 2 ).

We observed the prevalence of long COVID to increase with advancing age, with a proportion of 10.0% (7 out of 70) in the 18 to 24 age group, 29.4% (74 out of 252) in the 25 to 49 age group, and 34.4% (52 out of 151) in the 50 to 64 age group, with a significant trend for age ( p = 0.0010).

The other antibiotics did not exhibit a significant trend ( P < 0.001).

We observed an increase in the choice of laparoscopic approach during the study period (2016: 12%, 2017: 13%, 2018: 15%, 2019: 23%) and found a significant trend ( p < 0.001) in the Cochran-Armitage test (Fig. 2 ).

066), and a post hoc linear contrast showed a significant trend ( F (1,94) = −6.02, β = −3.33, p < .001), indicating that there was a linear relationship among the corrected recognition scores to novel picture categories.

Additionally, tumors bearing MGMT methylation had a significant trend toward lymph node metastasis ( p = 0.001), lymph invasion ( p = 0.005), venous invasion ( p = 0.004), perineural invasion ( p ≤ 0.001), distant metastasis ( p ≤ 0.001) and relapse ( p = 0.008).

In the PENS-Diet group, the median values received a score of 2 (range 1–4), representing a significant trend towards constipation ( p < 0.001).

There was a significant trend (Spearman’s ρ = -0.66, N = 33, P<0.001) for villages with lower kdr frequencies in 2017 to show a higher increase over subsequent years ( Fig 3 ).

A significant trend in knowledge score was observed with an increase in the level of education ( p < 0.001), with an effect size of 0.092.

A significant trend of increasing risk from the low-risk to the very high-risk group was observed ( P <0.001, Cochran–Armitage trend test).

In all models for HPDI ( Table 2 ), there was a significant trend ( p < 0.001–0.037) of lower risk of respiratory infection with higher consumption of healthy plant foods.

There was a significant trend that treatment in asymptomatic patients increases with colony count in urine culture (p< 0.001).

There was a significant trend that the longer the duration of drug use, the higher the improvement rate relative to 11% with < 30 days of use ( p < 0.001).

A significant trend for higher Klotho levels with higher intake of a specific nutrient was found for carbohydrates ( p < .001), total sugars ( p < .001), dietary fibers ( p < .001), vitamin D ( p = .05), total folates ( p = .015), and copper ( p = .018) (Table S2 ).

A significant trend in the implementation of the HBCR programs in two groups was shown using chi-square test and independent t -test and variance with repeated measurements ( p < .001).

There was a significant trend difference between the intervention and control populations in all forms quarterly TB notification rates (1.007, 95%CI 1.003–1.011, p = 0.001), as well as significant level change difference (1.036, 95% CI 1.014–1.059, p = 0.001).

Multivariate analysis demonstrated that there was a significant trend (p = 0.001) for children of patients over spouse in disclosure of "prognosis of disease".

Further, the number of sickle-shaped blood vessels was associated with distant metastasis and OS, with a significant trend toward a poor prognosis (metastasis P < 0.001, Cox; OS P < 0.001, Cox) observed for patients with more than 100 such vessels in large maximal tumor sections.

Among the total population sample, there was a significant trend for an increase in NVT carriage over the survey years in the rural site (Chi squared test for trend p < 0.001) and but not in the urban site (Chi squared test for trend p = 0.36).

Results There was a significant trend toward greater intensity of chronic histology changes along the KDRI quartiles (χ 2 = 20.8; P < .001), including interstitial fibrosis, tubular atrophy, mesangial matrix increase and arteriolar hyalinosis.

Consistently, when RDW was assessed as quartiles, compared with the reference group (quartile 1, RDW ≤12.4%), the HRs of recurrence of ischemic stroke was 1.372 (95% CI=0.671–2.805, P=0.386) in quartile 2 (12.8%≥RDW>12.4%), 1.835 (95% CI=1.222–2.755, P=0.003) in quartile 3 (13.3%≥RDW>12.8%), and 1.732 (95% CI=1.114–2.561, P<0.001) in quartile 4 (RDW>13.3%), with a significant trend test (P<0.001) after adjusting for covariables.

Follicular stimulating hormone levels showed a significant trend among all participants (V B : 12.51 ± 1.72, V 3 : 13.54 ± 1.41, and V 12 : 13.10 ± 1.67 IU/mL; p < 0.001).

A significant trend toward a higher clinical success rate was noted in the group undergoing prophylactic angioembolization (100% vs. 82.1%; p = 0.001).

There was a significant trend towards higher ISS in the HEMS group compared EMS in the cohort overall, as well as within each separate injury severity group (p < 0.001) (Fig. 3 , Table 1 ).

However, at postoperative day (POD) 1, there was a significant trend toward an increase of albumin, hemoglobin and calcium in the ERAS group compared with the control group ( p < 0.001), which continued at POD 3 ( p < 0.05).