The compound exhibited a significant trend toward lower IL-11 levels, resulting in a 28.4% decrease in secretion compared to the TGF-β1-stimulated group (p = 0.0415).
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A separate analysis of private costs for each wealth category for cases in Kilosa and Turiani ( S1 Table ) confirm significant cost differences by location, and found a significant trend in the total private costs paid by wealth category only in Kilosa (p = 0.042).
The Cochran-Armitage trend test indicated a significant trend in more reported TMF use over time, increasing from 17% to 28% and most recently 42% ( z = − 2.03, p = 0.042; Table 4 ).
Unfortunately a significant trend was observed for smoking status from 11.05% in phase 2 to 16.83% in phase 4 (p = 0.042).
However, a linear-by-linear association test across tertiles demonstrated a significant trend ( P = 0.042).
Stroke hazard was also 45% higher in the highest versus lowest TyG tertile, demonstrating a significant trend ( p = 0.042).
As previously reported [ 26 ], the majority of the EGFR -mutant tumors exhibited pEGFR, with a significant trend toward an association between EGFR mutation and pEGFR (Fisher’s exact test: P = 0.0425) (Fig.
Nevertheless, a significant trend across RCII quartiles was observed in all models (P for trend < 0.001 for Models 1 and 2; P = 0.043 for Model 3), supporting an overall dose–response pattern.
We then combined risk genotypes and found a significant trend toward an increased neuroblastoma risk with the accumulation of risk genotypes (adjusted OR =1.26, 95% CI =1.01–1.58, P =0.043).
VUE was associated with gestational hypertension Four studies demonstrated a significant trend toward increased gestational hypertension risk in VUE-affected pregnancies (OR = 1.41, 95% CI: 1.01–1.97; p = 0.043; Figure 3 ) ( 2 , 7 , 16 , 20 ).
Regarding thyroid sensitivity indices, a significant trend across OBS quartiles was observed for TFQI ( P = .043), with the Q 4 group showing a lower value compared to Q 1.
Quartile-based analysis showed a significant trend ( P for trend < .001); compared with the reference quartile, the reported ORs were 2.82 (95% CI = 1.09–7.32; P = .043) and 3.70 (95% CI = 1.72–7.94; P = .003). 3.3.
At the local level as well, in medium ecosystems, we observed a weak, yet marginally nonsignificant, trend of resource flows increasing species diversity (Figure 4 , p = 0.070) and a significant trend increasing biomass (Figure 4 , p = 0.043) in connected ecosystems relative to those that were unconnected (M M vs.
However, there was a significant trend that early migrating species tended to advance, and late migrating species tended to delay, their departure dates (r s = 0.32, df = 39, P = 0.044, Fig. 1 , Table S1 ).
Intriguingly, σ cyto was observed to fall from the baseline value in all cases following exposure to COVID-19 or the vaccine; both the Vaccinated and Recovered populations showed a significant trend starting at baseline and slowly moving to a terminal value of around 0.3 S/m after approximately 6 weeks (Vaccinated, * p = 0.044) to 10 weeks (Recovered, *p = 0.036).
We found a significant trend that correlated activated Akt (pAkt) and the combined status of IL-6 positive/pSTAT3 positive ( n = 94; p = 0.044) and between the combined status of pAkt/IL-6 positive and pSTAT3 ( n = 94; p = 0.029).
Overall, there was a rise in the utilization of antireflux surgery from 2004 until 2009 but a steady decline since then with a significant trend (p=0.044).
26.3%), and the additive model indicated a significant trend of increasing risk with increasing T allele number (OR = 1.50; p = 0.044).
Overall increase was 2.3 % in clipping and 13.1 % in coiling; a significant trend was found in endovascular procedures (p = 0.044).
Newly treated patients also exhibited significant trends in resistance rates to isoniazid, ethambutol, and streptomycin (all P values of <0.05), whereas only streptomycin resistance showed a significant trend in retreated patients ( P = 0.0447).
The adjusted proportion of an HbA1c level of ≥6.5% showed a significant trend across the WBC quartiles (1.1%±0.3%, 1.2%±0.3%, 1.9%±0.3%, and 2.0%±0.3%, respectively in Model 4; P =0.045) after adjusting for confounders.
In patients with luminal A, there was a significant trend toward shorter overall survival for those with tumors having high EZH2 expression compared to those with tumors having low EZH2 expression ( p =0.045).
Additionally, they showed a significant trend towards better event-free MR recurrence (98% vs. 86.7%, P=0.045) ( 11 ).
This effect was confirmed as a significant trend in metabolic response with increasing weeks of treatment (cohorts) (likelihood ratio chi-square = 4.00, p = 0.045).
The proportion of patients achieving full MRC score within one week also showed a significant trend among the groups (EFG group, 80%; PE group, 50%; IVIg group,12.5%, p = 0.045). the proportion of unaided walking patients in EFG group was higher than PE and IVIg group without statistically differences (80% vs. 50% vs. 37.5%, p = 0.39). the GBS-DS and INCAT scores in EFG group were slightly lower than PE and IVIg group.