PD-1 −/− HSC recipients at the peak of disease (day 45) demonstrated no significant difference in splenic CD4 or CD8 T cell populations although a small trend toward increased expression in PD-1 −/− HSC recipient CD8 T cells was noted (Figure S2 in Supplementary Material).
These findings highlight that even though the presence of a small trend would lead to a small bias in the estimation, the quality of the estimate computed using all the control data can be better than that computed using only the concurrent control data.
Although a small trend was evident, there was no significant difference in reporting health benefits between actions in the pre-implementation stage compared to those where actions were underway.
The figure shows that observed vancomycin concentrations are described without bias in all subpopulations, with the exception of the group with the worst kidney function (CKD-EPI < 30 mL/min/1.73 m 2 ) in which a small trend towards under-prediction can be seen.
There was a small trend for a relative astrogliosis with AD (Extended Data Fig. 3g, online resource).
A small trend toward stronger heterogenicity during membrane sheet incubation has been observed in previous studies also for other proteins that are not subject to cleavage ( 38 , 40 ).
[ 18 ] also exposed freshly excised, viable porcine vocal fold epithelium to hydrogen peroxide for 2 h and reported that exposure to ROS did not significantly alter transepithelial resistance, although a small trend for a decreased concentration of epithelial junctional complex protein was observed.
There was a small trend towards greater efficacy of SLT without PGA medications, and perhaps larger numbers of patients may show a difference.
Delayed Graft Function (DGF) Our primary marginal-matched analysis revealed a small trend for a lower DGF-rate of 9.2% in the HMP group versus 16.1% in the SCS group ( Table 4 ); however, the difference did not reach statistical significance (mean difference: −6.9 [−14.1; 0.4], p = 0.063).
A small trend towards higher antibody responses was observed when mice were vaccinated with ISDmut, especially against p15E/TM when only primed and against gp70/SU when boosted ( Supplementary Figure S5C ).
However, we found a small trend of longer TL in females when using the TRFI method, but this trend was not statistically significant (mean = −0.267, HPDI = [−0.730 : 0.141]).
However, after the first day at 82 dB SPL (purple curve, Supplementary Figure 1D ), there was a small trend toward a greater duration of both visits and licks during tritone and 7th chords (ANOVA without silence, visit duration, lick duration, sound effect g1,g2,g3,g4 , p < 0.03, post-hoc Oct and 5th vs.
When a subgroup of patients who stayed in the ICU for more than 5 days was analyzed, although a small trend toward mortality reduction was noted (25.5% in group 1 and 30.3% in group 2; relative reduction of 16%), this difference did not reach statistical significance.
In TOPAZ, there was a small trend toward improved household productivity in participants treated with alemtuzumab, seen as a decrease in the mean hours lost in Year 5 (6.11) compared with baseline (8.57), and an increase in mean work output in household chores in Year 2 (21.22%) relative to baseline (16.08%) ( Figure 10(a) and ( b )).
3c and d ), in the case of the doubly charge species, several bands were observed with a small trend toward more compact structures with the decrease of the solution pH value ( Fig. 3g and h ).
Indeed, we observed lower richness and a small trend for lower Shannon diversity in samples from mice when they were weaned at 4 weeks of age compared to mice sampled at 11 and 18 weeks of age in both housing systems irrespective of generation.
However, considering the mean differences, there is a small trend toward more PA in the intervention group.
There was a small trend toward lower cybersickness in the peripheral-cued condition, but it was not statistically significant.
We observed a small trend of second doses given within a few months after the first dose instead of 28 months later.
17 – 18 , 21 – 24 Three studies included in an earlier review 9 showed a small trend favouring ET alone but found no statistically significant difference ( Table 2 ).
Conclusion In summary, a community-based, wellness policy implemented into HS programming showed a small trend toward improvement in BMI between year 1 and 2 of programming but not to a statistically significant level.
A small trend towards a greater bacterial reduction with longer washing times was observed for both test products (except 3 mL CHG; Table 1 ).
The split group analysis showed a small trend of modulation by CS scores: only the low-CS-scores group showed Interference, but it is difficult to draw any conclusions from this result since the high-CS-scores group did not show any difference between conditions, let alone an interference effect.
At the last follow-up, none of the clinical scores were significantly better in the “Recenter” group, but we think there could be a small trend towards an improvement with the Recenter.
In the baseline condition (black circles) where none of the segments was attenuated or amplified, the four segment weights descriptively showed no primacy effect, but a small trend for a recency effect.