In a recent retrospective study of CT examinations performed over a 10-year period in 20,242 adult inpatients (10,121 untreated and 10,121 treated with IV contrast media) with sufficient serum creatinine data, in order to determine the effect of IV low-osmolar contrast media (LOCM) on the development of post-CT CIN, stratified by pre-CT eGFR in patients with stable renal function, it has been observed that IV LOCM is a risk factor for nephrotoxicity in patients with a stable eGFR <30 mL/min/1.73 m 2 , with a trend toward significance at 30–44 mL/min/1.73 m 2 , whereas it does not appear to be a nephrotoxic risk factor in patients with a pre-CT eGFR ≥45 mL/min/1.73 m 2 [ 37 ].
← all phrases
“a trend toward significance”
In the literature
116 , 117 In early dcSSc, abatacept failed to improve skin score, though it showed a trend toward significance as well as manageable AEs. 118 In contrast, numerous published cases exist for the use of abatacept in patients with morphea and show promise for future potential large‐scale trials. 119 , 120 , 121 A retrospective compilation of eight cases of juvenile morphea showed no progression
( 12 ) reporting a trend toward significance.
The P ≤ 0.05 was considered as a significant difference, and P ≤ 0.10 was considered as a trend toward significance.
We consider this finding an improvement upon the AUROC presented in our first report [ 2 ], where we demonstrated a trend toward significance but did not meet the threshold for statistical significance ( p = 0.057) and had broad 95% confidence intervals (0.571 to 1.009) in the logistic regression.
Among them, 20 fatty acids changed significantly, and two fatty acid showed a trend toward significance.
There was, however, a trend toward significance when we queried if those with PCR positivity were more likely to have evidence of acute hepatitis (44% of PCR negative patients vs. 64% of PCR positive patients did; p = 0.08).
While we previously showed that GR are more important than MR for the anxiety-like behaviors seen following SD and mTBI, there was also a trend toward significance for MR, and there were no significant differences noted between GR or MR on anxiety-like behaviors [ 9 ].
In RD, we found pERK increased significantly in detached retina at day 7 and had a trend toward significance at day 3 compared to control retina ( P = 0.0025 day 7 and P = 0.0960 day 3); pERK accumulation was observed in Müller glia endfeet in the GCL and was very abundant in the inner nuclear layer (INL), co-localizing with Sox2 in the Müller glia nuclei with weaker levels in the cytoplasm.
In the treated group, the reduction in EPO doses showed a trend toward significance and the reduction in ERI was significant; in contrast, in the control group both parameters showed insignificant changes.
REST and surrogate AD markers Partial correlation analyses, co-varying for APOE genotype, demonstrated associations with hippocampal volume, entorhinal cortex volume, whole brain volume and a trend toward significance for ventricular volume ( Table 2 ).
In the univariate analysis, the length of stay in hospital (odds ratio [OR], 2.77), operative time (OR, 2.74), and amount of time spent on treatment/surgery (OR, 15,610.9) were found to be significant factors, whereas blood loss (OR, 1.20) only showed a trend toward significance.
No significant behavioral deficits in fear conditioning or Morris water maze were observed at any time point, but a trend toward significance was found in cued fear conditioning at 12 weeks after injection.
Compared to 10,644 noncaregivers, 209 family caregivers exhibited lower health utility and mental component summary scores and a trend toward significance on lower physical component summary scores, suggesting poor mental HRQoL and overall health in dementia caregivers [ 41 ].
Additionally, a trend toward significance of a higher prevalence of HPV-16 infection was observed in patients with cancer in the base of tongue as compared with the patients with cancer in other sites of HNC ( χ 2 = 3.455, r = +0.194, p = 0.063) (Table 1).
Sex distribution did not differ significantly between the weight groups ( P = .114 in the deficiency group and P = .052 in the insufficiency group, indicating a trend toward significance in the latter).
The difference between symp-HD and pre-HD in the rate of putamen volume loss exhibited a trend toward significance (see Figure 1 ; see Tables S1 and S2 for a full inventory of longitudinal within- and between-group regression coefficients and their statistical significance).
After adjusting for the same five covariates, an increased plasma ACE level demonstrated a trend toward significance with the homozygous +9 patients ( Fig. 2 ).
We observed a significant inverse relationship between flow state and the LF/HF ratio in the pre-performance phase, while observing a trend toward significance for a positive relationship between the LF/HF ratio and flow as well as LFms 2 and flow during performance.
However, even in our patients with childhood onset there was a trend toward significance for reduced global cerebellar volume.
The p -values in the regression analysis of ATG4B/4D with age were very small despite the low R 2 ( Figure 1 A,D), indicating a trend toward significance despite the high variability of the sample data between individuals.
At rest, k-t High images contained significantly smaller artifact than k-t Hybrid images though only a trend toward significance was seen in the corresponding images during stress.
Familiar music was not a statistically significant predictor ( p = 0.062, OR = 3.411, 95% CI 0.939–12.391), although it showed a trend toward significance, suggesting that participants experiencing familiar music were more likely to report an internal spatial localisation.
A further two pathways showed a trend toward significance (i.e.
At the end of 6 months, the subjects receiving the sugary soft drinks displayed more visceral, skeletal muscle, and liver fat and higher serum triglycerides and cholesterol compared with the group drinking milk, with a trend toward significance in the other two groups.