Barely Significant
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a trend toward significance

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In the literature

In a recent retrospective study of CT examinations performed over a 10-year period in 20,242 adult inpatients (10,121 untreated and 10,121 treated with IV contrast media) with sufficient serum creatinine data, in order to determine the effect of IV low-osmolar contrast media (LOCM) on the development of post-CT CIN, stratified by pre-CT eGFR in patients with stable renal function, it has been observed that IV LOCM is a risk factor for nephrotoxicity in patients with a stable eGFR <30 mL/min/1.73 m 2 , with a trend toward significance at 30–44 mL/min/1.73 m 2 , whereas it does not appear to be a nephrotoxic risk factor in patients with a pre-CT eGFR ≥45 mL/min/1.73 m 2 [ 37 ].
116 , 117 In early dcSSc, abatacept failed to improve skin score, though it showed a trend toward significance as well as manageable AEs. 118 In contrast, numerous published cases exist for the use of abatacept in patients with morphea and show promise for future potential large‐scale trials. 119 , 120 , 121 A retrospective compilation of eight cases of juvenile morphea showed no progression
Upcoming treatments for morphea.
Immun Inflamm Dis · 2021 · PMC8589364
We consider this finding an improvement upon the AUROC presented in our first report [ 2 ], where we demonstrated a trend toward significance but did not meet the threshold for statistical significance ( p = 0.057) and had broad 95% confidence intervals (0.571 to 1.009) in the logistic regression.
In RD, we found pERK increased significantly in detached retina at day 7 and had a trend toward significance at day 3 compared to control retina ( P = 0.0025 day 7 and P = 0.0960 day 3); pERK accumulation was observed in Müller glia endfeet in the GCL and was very abundant in the inner nuclear layer (INL), co-localizing with Sox2 in the Müller glia nuclei with weaker levels in the cytoplasm.
No significant behavioral deficits in fear conditioning or Morris water maze were observed at any time point, but a trend toward significance was found in cued fear conditioning at 12 weeks after injection.
ASNTR 2022 Abstracts
Cell Transplant · 2022 · PMC9067030