a trend toward significanceP = 0.15
The gene for OATP‐C ( SLCO1B1 ) was significantly reduced ( P < 0.001) in the high‐risk cluster, and a trend toward significance in the gene for bile salt export pump was also apparent ( P = 0.15) (Supporting Fig.
The gene for OATP‐C ( SLCO1B1 ) was significantly reduced ( P < 0.001) in the high‐risk cluster, and a trend toward significance in the gene for bile salt export pump was also apparent ( P = 0.15) (Supporting Fig.
This effect was present for moderately negative images that were watched (5.40) or labeled (4.97), t (27) = 3.48, p < .01, but showed only a trend toward significance for extremely negative images that were watched (7.60) or labeled (7.52), t (27) = 1.63, p < .15.
1b ) increased with disease severity with a trend toward significance (moderate, 1027.56 pg/mL; severe, 1136.92 pg/mL; critical, 1315.68 pg/mL, p = .153), and levels also rose post-tocilizumab (moderate, 1525 pg/mL, p = .011; severe, 1402.68 pg/mL, p = .046; critical, 1776.24 pg/mL, p = .0019).
The multiple regression revealed that GT spurs ( P = .002) and AHI ( P = .032) were predictive of the Patte stage and statistically significant, whereas the acromial spur showed a trend toward significance ( P = .159) ( Table II ).
Long‐rank test demonstrated a significant correlation between poor OS and a large number of distinct CGH segments in recurrent tumors ( P = .024) (Figure 3 A), and a trend toward significance for a high fraction of the genome altered in treatment‐naive tumors ( P = .16) (Figure 3 B).
Multivariate analysis in this setting showed a trend toward significance (HR 2.41, CI 95% 0.70–8.31, p = .16).
In the GDH/NAAT arm, the difference showed a trend toward significance ( P = 0.16).
Education levels show a trend toward significance, with 60.0% of HBI OC participants having tertiary education compared to none in the HBI OV group ( p = 0.16).
We observe a trend toward significance ( p = 0.18) but no significant difference in new RRT requirements between study groups.
Achieving a pathologic complete response ( n = 10) to systemic therapy was associated with a favorable recurrence-free survival after resection, with a trend toward significance (HR, 0.345; 95% CI, 0.067–1.785; P = 0.187).
However, we observed a trend toward significance in OS with patients who experienced irAEs compared to those who did not experience irAEs (median 16.4 vs. 6.8 months, p = 0.19, Figure 3 A).
Variables with statistical significance or a trend toward significance (p < 0.2) were included in the multivariate analysis, which was performed using logistic regression to estimate the corresponding coefficients and odds ratios (ORs) for selected predictors.
Univariable analysis showed that many variables had a trend toward significance ( P < 0.2) for association with the presence of individual, or groups of infectious agent(s) (Table 5 , Table 6 , Additional file 2 : Table S1, Additional file 3 : Table S2), and these were entered into the multivariable logistic regression analysis, together with variables having significant associations ( P ≤ 0.05).
However, a trend toward significance was observed between cholesterol levels and SJ (p = 0.20), while no correlation was found between SJ/TJ and the other recorded metabolic parameters. 3.2.
A logistic regression model was conducted to evaluate clinical and sociodemographic variables that were either statistically significant in the univariate analysis ( p < 0.05) or demonstrated a trend toward significance ( p < 0.2), in order to identify potential risk factors associated with a reduction in PLT levels.
Variables with a trend toward significance ( P <0.20) and a potential confounding relationship were selected for inclusion in multivariable models.
Variables that were statistically significant or had a trend toward significance ( p < 0.2) or were of a priori clinical significance were included in a multivariable analysis with forward stepwise ordinal logistic regression, to evaluate independent factors associated with medication non-adherence.
The multivariate logistic regression models included variables that showed statistical significance or a trend toward significance ( p < 0.20) in univariate analyses.
We sought further replication of the two chromosome 1 regions in an additional set of cases and controls from the United States ( Table 1 , Supplementary Table 2 ); rs7412746 clearly replicated (OR=0.86, P =0.0076, one-sided; meta-analysis of all three replication cohorts OR=0.89, P =1.5 × 10 −5 ), with rs3219090 showing a trend toward significance in the expected direction (OR=0.95, P =0.20, one-sided; meta-analysis of all three replication cohorts OR=0.91, P = 3.4 × 10 −3 ).
Combinational treatment showed significance in comparison to control by week five (p = 0.029), curcumin alone showed a trend toward significance (p = 0.20), and NSC treatment showed no significance (p = 0.55).
Factors with a trend toward significance ( p < 0.20) were initially considered for inclusion in the multivariable analysis.
Any baseline patient demographics and surgery characteristics that showed significance or a trend toward significance ( p < 0.2) from univariate analysis were inputted into a binary regression analysis to determine which factors were most associated with the development of postoperative complications.
A trend toward significance was observed also within the Ruminococcaceae family ( p = 0.2) CTRL 6.9% (5.5–8.3), LA 8.0% (6.7–9.4).
Additionally, a trend toward significance ( p < 0.2) for T . gondii seropositive was noted for cats that were non-pedigree, had outdoor access, lived in a rural area, were PCR-positive for CMhm and PCR-positive for at least one feline vector borne pathogen (FVBP).
To determine independent correlates of pCR, variables with a trend toward significance on univariate testing ( p <0.20) were entered into a forward, stepwise multivariable logistic regression model ( p <0.05 for entry, p <0.10 for exit).