Barely Significant
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a weak trend

835 sentences · 835 papers · 1,848 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

For larotrectinib, no relationship between exposure and toxicity was described in the approval report ( n = 66); in exposure-toxicity analyses for entrectinib there is a weak trend between higher exposure and frequency of serious AEs, although this was not significant after correction for gender in the analysis ( n = 263).
Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology.
Clin Pharmacokinet · 2023 · PMC10519871