Barely Significant
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an apparent trend

91 sentences · 91 papers · 2,292 search hits before verification · confirmed specimen

Sighted at

p=0.286

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

3 , 34 Across various CCA studies, the presence of cirrhosis, as well as hepatitis B and C, was not associated with shorter disease‐free survival, 34 and the results on OS in patients with cirrhosis or chronical hepatitis B infection are disparate, with an apparent trend towards shorter OS in these patients. 35 , 36 To date, the vast majority of iCCA studies investigating clinical prognostic factors do not report on either body composition, steatosis, or MAFLD as an iCCA aetiology or as a prognostic factor. 34 , 37 Recently, an Italian study reported that patients fulfilling NASH criteria had an inferior OS after iCCA surgery but did not observe a difference in TTR between aetiologies.
Furthermore, the release of NAG contained in azurophilic granules was also significantly decreased after 60 min of stimulation ( Figure 3B ), which is consistent with our flow cytometry data ( Figure 3A ), while the release of MMP-9 from gelatinase granules remained unaltered despite an apparent trend ( Figure 3D ).
There was no difference in the primary endpoint of progression-free survival among the groups, and there was an apparent trend towards inferior overall survival in the experimental arm (14.4 vs. 19.8 months; HR 1.42; 95% CI 0.76–2.68).
ATR Inhibition in Advanced Urothelial Carcinoma.
Clin Genitourin Cancer · 2023 · PMC10750798