Barely Significant
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an important trend

593 sentences · 593 papers · 1,689 search hits before verification · confirmed specimen

Sighted at

p=0.066

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

More recently, protein language models such as ESM-2 and ProtT5 have further advanced sequence-based annotation by learning high-capacity representations directly from large-scale unaligned protein corpora, highlighting an important trend toward integrating protein-language-model-derived features with structural models. , The emergence of AlphaFold2 has inaugurated a new era in structure-based function prediction, reinforcing the principle that structure determines function. , Studies such as DeepFRI leveraged experimentally determined structural databases for annotation, while Struct2GO and StructSeq2GO combined AlphaFold2 predictions with GNNs to improve accuracy.