“an increasing trend”

The overall rate of antiretroviral treatment (ART) initiation within one year of age was 37% (157/429), with an increasing trend from 28 to 52% ( p <0.001).

The model suggested an increasing trend in sCr levels during pregnancy in cases who later developed preeclampsia ( p < 0.001; Supplementary Fig. 1).

The total amount of opioids dispensed in the first prescription after surgery decreased in the 2 years following the CDC guideline release, compared with an increasing trend in the 2 years prior (prerelease trend: 1.43 MME/month; 95% CI, 0.62 to 2.24 MME/month; P = .001; postrelease trend: −2.18 MME/month; 95% CI, −3.01 to −1.35 MME/month; P < .001; trend change: −3.61 MME/month; 95% CI, −4.87 to −2.35 MME/month; P < .001).

Concurrently, UACR demonstrated an increasing trend in albuminuria across the quartiles (p < 0.001).

After the administration with FEJ, KIS, KHS, KJS, all the above indicators showed an increasing trend (Fig. 2 ), compared with the model group, HGB and RBC levels in mice administered with two doses of KIS were increased significantly ( P < 0.001), and the HCT levels of the low-dose KIS were increased significantly ( P < 0.01).

However, the mean age at menarche shows an increasing trend from the poorest to richest wealth quintile and the difference between the women of the poorest wealth quintile with other categories was significant (p<0.001) ( Figure 3 ).

The crude death rate of cancer in the six provinces of northwest China from 2013 to 2021 showed an increasing trend (AAPC = 3.96%, p < 0.001).The age-standardized mortality rate of cancer in six provinces in northwest China was overall stable from 2013 to 2021 (AAPC = − 0.13%, p = 0.928) but exhibited a decreasing trend from 2017 to 2021 (AAPC = − 5.64%, p = 0.047).

The prevalence of ‘wheeze ever’ showed an increasing trend (15.0% in 1995, 10.8% in 2000, 15.2% in 2010, and 16.4% in 2022) during the study period ( P < 0.001).

There was an increasing trend towards modifiable UDTC risk factors coprevalence with increasing education and annual family income (all p<0.001).

F055 showed distinct sesquiterpene pattern with high γ-maaliene (12.50%) and β-elemene (9.73%), and they showed an increasing trend and were positively correlated with odour intensity ( p < 0.001).

Sample seroprevalence in muskoxen varied geographically with an increasing trend of exposure on NW Victoria Island (from 0% to 36.8% between 2016 and 2022; Kendall tau = 0.283, p = 0.001).

An increasing trend was observed in percentage of obesity with age with a decline seen in participants with ages older than 55 years ( P < 0.001).

An increasing trend in precipitation was observed over the study period (z = 3.5, p < 0.001).

There is no clear pattern of increase in UV Index in Sweden, England, and Australia ( p > 0.05); however, there was an increasing trend of UV index in the USA (β = 0.047; p < 0.001).

There was an increasing trend in the level and prevalence of elevated lipid profile markers across the SUA quartiles ( p < 0.001).

When the number of months worked exceeded 56 months, the risks of all-cause mortality exhibited an increasing trend (Fig. 2 D) ( P < 0.001).

For the barplots, significantly changing lipids showing an increasing trend or decreasing trend were selected by adjusted p- value <0.001 with a log fold change of <0 and >0, respectively.

As shown in figure 2F , the normalised MEP amplitudes in YG group showed an increasing trend at 5 min (120.18% (109.88%, 131.45%), p=0.001), 10 min (123.51% (114.37%, 133.39%), p<0.001) and 30 min (116.97% (107.56%, 127.21%), p=0.004) compared with baseline.

All the hematologic and inflammatory parameters showed an increasing trend from Group I to Group IV ( P < 0.001); in contrast, Hb and lymphocyte fraction tended to decrease (Table 2 ).

There was an increasing trend in solid tumors (80.6% vs. 70.7%, p < 0.001).

Moreover, there was an increasing trend in the median (inter-quartile range) of GDF-15 concentrations from the patients with no DR, mild NPDR, moderate NPDR, to VTDR (P < 0.001 for trend) ( Figure 1 ).

An increasing trend was observed in the administration of oral anticoagulants (OAC) (from 12.1% to 36.5%; p < 0.001) and PPIs (from 21.3% to 63.5%; p < 0.001) ( Figure 2 ).

Results Vegetation cover changes during 1982 to 2020 in the Tibetan plateau As shown in Figure 3 , between 1982 and 2020, nearly 89% of the alpine ecosystem in the Tibetan Plateau showed an increasing trend in vegetation cover, with a rate of change of 0.0019 per year for VCI ( p < 0.001) and 0.0096 per year for LAI ( p < 0.0001).

During the treatment period, the achievement of PASI 75, PASI 90, and PGA (1/0) showed an increasing trend ( Z =9.42 and P <.001; Z =8.53 and P <.001; and Z =3.14 and P =.002, respectively).

In these groups as well, sensitivity analyses excluding the year 2020 confirmed an increasing trend in sudden death–attributable mortality in both sexes [AAPC: +2.7% (95% CI: 1.8–4.0), p < 0.001 in men; and AAPC: +3.0% (95% CI: 2.0–4.5), p < 0.001 in women, respectively].