“an increasing trend”

There were significant differences in mean systolic (SBP, mean±SD mmHg: 102±12, 108±11, 112±12, 116±12) and diastolic blood pressure (DBP, mean±SD mmHg: 62±10, 66±8, 68±8.9, 70±9) across the four BMI groups with an increasing trend (p-values<0.0001).

In contrast, temperature and precipitation during this period revealed an increasing trend at mean rates of 0.39 ± 0.02 °C ( P < 0.0001, MK test, two-sided, n = 10,330; Fig. 1d ) and 0.51 ± 0.26 mm/day per decade ( P = 0.027, MK test, two-sided, n = 12,668; Fig. 1e ), respectively.

As for Kp, an increasing trend was detected in 2017 ( p -value < 0.0001) from 2.51/1000 PD in 2015 to a peak of 3.24/1000 PD in 2019.

Pancreatic investigations using computed tomography (CT), MRI, and EUS conducted in five US academic medical centers demonstrated pancreatic findings in 42% of 216 asymptomatic HRIs; these included cysts (39%, mean: 0.55 cm in size), pancreatic duct dilation (2.3%) and solid mass (1.4%), and an increasing trend by age (14% among those <50 years, 34% in patients 50–59 years, and 53% in 60–69 years; p < 0.0001) [ 76 ].

The Mann-Kendall trend test showed an increasing trend between the top-cited articles’ citation density and their published time ( P < 0.0001) (Fig. 3 ).

Further, there was an increasing trend in both the proportion of women as senior authors (6% in 2018, 9% in 2019, 14% in 2020, 15% in 2021, and 18% in 2022, P < 0.0001) and percentage of total women authors (9% in 2018, 12% in 2019, 19% in 2020, 17% in 2021, and 20% in 2022, P < 0.0001) across the years ( Figure 2 ).

But, Glu concentration had an increasing trend in THP-1 cell line ( p = 0.0001).

As shown in Figure 8 , there was an increasing trend in the U content over time ( p < 0.0001) for all gene segments in both viruses, with the exception of the HA segment of H3N8 CIV, in which the U content gradually decreased over time.

compared to the naive animals, and showed an increasing trend at higher doses of LdWT LLO infection (Figure 2 D, one-way ANOVA, p < 0.0001; Figure S3 in Supplementary Material).

Over time, a consistent decreasing trend in CVs (p < 0.0001) ( Figure 1b ) and an increasing trend in %Adequacy across all concentrations (p < 0.0001) ( Figure 1c ) were observed.

On the other hand, other probiotics showed no significant trends of change, and Lactobacillus salivarius showed an increasing trend from the normal subjects to the CRC patients ( p < 0.0001) ( Figure 1 A).

The age-specific HSV-2 seroprevalence of HIV-infected men was 23.9% for the 20s, 48.6% for the 30s, 57.1% for the 40s and 69.2% for the 50s, respectively, showing an increasing trend by age ( p <0.0001).

The trend test also showed an increasing trend in the findings ( p < 0.0001).

From July 2020 to December 2021, the average time from last data collected to publication was 8.9 ± 4.1 months, with an increasing trend over time ( R = 0.9444, p < 0.0001).

Epidural LOR measurements had an increasing trend with higher thoracic level ( p < 0.0001).

Age exhibited an increasing trend, with an average increase of 0.5 years per year ( p < 0.0001).

In the absence of BPs, vWF expression by the endothelial growth media stimulated pMSCs showed an increasing trend over the experimental period with a significant 4-fold up-regulation (p < 0.0001) in expression at the end of ten days.

The absorbance measure of the IEC proteins was dose-dependent ( r = 0.994, P < 0.0001) and showed an increasing trend with increasing IEC protein coating concentration ( F = 397.007, P < 0.0001) (Figure 8 A).

Results: The preparatory online modules had a significant effect (p=0.044) on the ECL of the scenario leaders, with the CG having an increasing trend over four sessions (b=0.33, p=0.0016) and the OG having a decreasing trend over four sessions (b=-0.16, p<0.0001).

Tests of the year main effect revealed a decreasing trend for wrist ( p <.0001), an increasing trend for vertebral ( p =.0012), and no statistically significant change for humerus ( p =.2226).

Notably, the positive rates of sputum cultures showed an increasing trend year by year except for 2021 ( p <0.0001) ( Figure 2 A).

Results of the Cochran–Armitage trend test revealed a significant decreasing trend in rates of involuntary hospitalization (15.94% in 2006 and 0.78% in 2019, Z = 5.33, p < 0.0001 ) and an increasing trend in LAI use at discharge among involuntarily hospitalized individuals (16.77% in 2006 and 50.00% in 2019, Z = 6.81, p < 0.0001 ).

An increasing trend was observed for neurological/psychological diseases (P value <0.0001).

Among specific types of CAKUT, an increasing trend was found in renal anomalies (from 0.26 to 0.55 per 1000 live births, P < .0001).

Facility-Based Hemodialysis Initiations We observed an increasing trend in the rate of initiations receiving facility-based hemodialysis before the pandemic (incidence rate ratio [IRR], 1.0027; 95% CI, 1.0016 to 1.0038; P < 0.0001), meaning that each month the number of new patients starting facility-based hemodialysis increased by about 0.27%.