“an increasing trend”

After adjustment for selected covariates, there was an increasing trend in the adjusted PRs for cancers of all sites by duration of diagnosed diabetes among men ( P < 0.0001 for linear trend) ( Fig. 1 A ) and women ( P < 0.0001 for linear trend) ( Fig. 1 B ).

Results There was an increasing trend in overall firearm injuries between 2010 and 2020 among adults in this large integrated healthcare system ( p < .0001), primarily driven by non-self-inflicted firearm injuries ( p < .0001).

The overall prevalence of anti-HBc was 7.0%, with an increasing trend with age, from 0% in 18–20 years old group to 17.9% in 51–60 years old group ( χ 2 = 46.7965, p < .0001).

The result from the present study revealed that TDML showed an increasing trend (P < 0.0001) with an increase in both BSY inclusion level and ED. 3.5 Chemical composition and in-vitro organic matter digestibility of BSY-based silage The interaction effect of BSY inclusion level and ED for some chemical composition parameters are indicated in Table 7 while those parameters influenced by main factor effects are indicated in Table 8 .

Additionally, with the progression of the induction period, a decreasing trend in scleral fibers’ diameters was observed in the left eyes ( F = 31.85, P < 0.0001), while an increasing trend was noted in the right eyes ( F = 7.68, P = 0.0005).

The linear regression showed an increasing trend for the male/female stroke ratio of 1.252 ± 0.004 (r = 0.776; p<0.0001) in Brazil and 1.331 ± 0.006 (r = 0.580; p = 0.002) in São Paulo.

The age-specific HSV-2 seroprevalence of HIV-infected men was 23.9% for the 20s, 48.6% for the 30s, 57.1% for the 40s and 69.2% for the 50s, respectively, showing an increasing trend by age ( p <0.0001).

Facility-Based Hemodialysis Initiations We observed an increasing trend in the rate of initiations receiving facility-based hemodialysis before the pandemic (incidence rate ratio [IRR], 1.0027; 95% CI, 1.0016 to 1.0038; P < 0.0001), meaning that each month the number of new patients starting facility-based hemodialysis increased by about 0.27%.

An increasing trend in global health status from baseline was noted over 25 exposures ( p < 0.0001) (Figure S2 ).

The COPD-/CVD + group also showed an increasing trend, with a HR of 2.06 (95% CI: 1.47, 2.89),(All related p -values < 0.0001).

From 2000 to 2014 an increasing trend was observed in the reported % KPN NS to imipenem ( P < 0.0001) from 0.6% to 11.6% with an average annual percentage increase (AAPI) of 36.3% [95% CI: 39.8%–33%].

On the other hand, an increasing trend of underweight was found in boys and girls (P < 0.0001).

An increasing trend of GC infections was also observed, with a rate of 1.3% in 2009 and 6.0% in 2016 (p<0.0001).

Furthermore, after the introduction of ICIs, both total and cancer-related medical expenses per capita showed an increasing trend [β: $4.56K, standard error (SE): $0.27K, P<0.0001 and β: $4.54K, SE: $0.27K, P<0.0001, respectively].

Conversely, there was an increasing trend in the proportion of tetracycline-resistant Salmonella spp. in chickens ( p < 0.0001) ( Figure 1 a).

Over time, a consistent decreasing trend in CVs (p < 0.0001) ( Figure 1b ) and an increasing trend in %Adequacy across all concentrations (p < 0.0001) ( Figure 1c ) were observed.

Based on the data obtained, there is an increasing trend in the expression of the E2F2 gene in the MACI1 subset (in comparison to the MAIC2 group, Fig. 6 , P < 0.0001).

This analysis showed an increasing trend for TPs using the filgrastim biosimilar (from 34.4% in July 2015 to 49.8% in June 2016; p < 0.0001) compared with a decreasing trend for TPs using lenograstim (from 22.6% in July 2015 to 12.3% in June 2016; p < 0.0001) and pegfilgrastim (from 26.8% in July 2015 to 20.6% in June 2016; p < 0.0001).

Inexplicably, in the LR lines the response to CL in the initial five minutes of exposure showed an increasing trend over the selection cycles in replicates A and B ( df = 5; F A = 14.3, F B = 10.6; p = 0.0001).

Seroprevalence showed an increasing trend ( p < 0.0001) starting in the younger age groups: 6–9 years: 84.1%; 10–14 years: 88.7%; 15–19 years: 89.3%; 20–39 years: 93.1% and >40 years: 97.0%.

Analysis of 2,331,175 unique patients tested March-May 2020 demonstrated an increasing trend in SARS-CoV-2 NAAT positivity across Black non-Hispanic community progressive quintiles (from 7.8% to 17.2%, P < 0.0001) and Hispanic community progressive quintiles (from 8.4% to 15.5%, P < 0.0001) and a decreasing trend across White non-Hispanic community progressive quintiles (from 17.4% to 7.1%, P < 0.0001).

As shown in Figure 1 , UVM exhibited an increasing trend from 1975 to 2016, with an average annual percentage change (AAPC) of 2.6 (95% CI, 0.3, 4.9, p < 0.0001).

Results of the Cochran–Armitage trend test revealed a significant decreasing trend in rates of involuntary hospitalization (15.94% in 2006 and 0.78% in 2019, Z = 5.33, p < 0.0001 ) and an increasing trend in LAI use at discharge among involuntarily hospitalized individuals (16.77% in 2006 and 50.00% in 2019, Z = 6.81, p < 0.0001 ).

For MI ratio, group 2 (Lesotho, Indonesia, and Zimbabwe) showed an increasing trend (slope: 0.005, p < 0.0001), while other groups showed decreasing trends with slopes ranging from −0.009 to −0.001 (all p < 0.0002) ( Figure 4C , Supplementary Table 1 ).

Next, we analyzed the expression of cell cycle‐related protein after H 2 O 2 exposure and found an increasing trend of P21 protein expression level ( p < .0001; Figure 6d,e ).