“an increasing trend”

Interestingly, although the neutralization activity of AI-10 was significantly improved, the structural analysis did not find an increasing trend of polar interactions represented by hydrogen bonds ( Fig. 4C ), suggesting other enhancement mechanisms.

We identified an increasing trend in the incidence of dementia in Republic of Korea over 10 years.

Under the SSP2−4.5 scenario, Schoener’s D showed an increasing trend during the 2090s.

Validation and predictive performance Internal metrics Comparing the distribution of reported deaths across alert levels and regions, we generally observe an increasing trend in average deaths per million population, with some overlap between levels ( figure 3A ).

Despite the lack of statistically significant differences observed between the low-dose group (29.01 ± 8.40%) and the model group, an increasing trend was still apparent.

2.53 ± 1.42 P = 0.0556) We sought to ascertain whether bipolar spectrum and suicide-related variables followed an increasing trend from patients who never switched (N = 221) to early switchers, the most likely AEMS group.

There was no significant difference in the Chao and Shannon index among the three groups, however, all showed an increasing trend and decreased subsequently ( Table 2 ). 3.2.3 Composition of intestinal microflora of juvenile E. sinensis under different water temperatures The top 10 microorganisms at the phylum level in the intestinal abundance of juvenile E. sinensis reared at different water temperatures include Firmicutes, Proteobacteria, Bacteroidota, Fusobacteriota, Patescibacteria, Actinobacteriota, Campylobacterota, Gemmatimonadota, Verrucomicrobiota, and Acidobacteriota.

In general, they were showing an increasing trend of pH deeper soil layer i.e. with the increasing soil depth.

(6) Singapore With the exception of Phase II, all showed an increasing trend.

In this study, we found that TFDM could significantly up-regulate the expression of p-Akt and SRC in CIRI rats, and the effect showed an increasing trend with the increase of the drug dose.

Therefore, according to our surveillance, there was an increasing trend in the prevalence of pvl -positive MRSA among SSTI isolates in Chinese children, which was probably connected with the increase in deep infections.

In Germany, the number of new cases of this tumour entity shows an increasing trend of almost 14,000 cases diagnosed annually.

Although controlled randomized clinical trials are considered the gold standard to define the efficacy of treatment and are most suitable for finding relevant biomarkers, there is an increasing trend to emphasize and appreciate the opportunities and benefits of data arising from real-world evidence (Di Maio et al. 2020 ; Nazha et al. 2021 ).

Our study observed an increasing trend in risk of mechanical ventilation with age was observed in the current study, except for those aged ≥80 years.

An increasing trend of expression of miR-20a as a positive regulator was clearly observed in the rats that received PCL/HA/BG compared to the control and PCL groups even PCL/HA groups 30 days post-operation.

Mean serum 25(OH)D concentrations showed an increasing trend over time and a remarkable increase in 2021 ( Figures 5–7 ).

The fluorescence signal intensity of SOSG showed an increasing trend with increasing ultrasound irradiation time (Figure 3d ), indicating that the PO/D‐PGs system could generate 1 O 2 under the irradiation of LIUS.

Perfluorooctanesulfonic acid (PFOS) was the only chemical exhibiting an increasing trend for both endpoints, while not directly agonizing AR and ERα.

An increasing trend of LOS in the ICU was observed among the three groups, with the P for trend being 0.02, while no trend was seen for LOS in the hospital (P for trend = 0.77).

The expression levels of the tested genes in the infected cells treated with piceatannol showed an increasing trend within 48 h.

glyptostroboides seeds alleviated the lipid peroxidation process; thus, the MDA content did not change significantly, although it showed an increasing trend.

Another kidney injury marker, NGAL, showed an increasing trend, but it was not statistically significant.

Transfer learning techniques have been gaining popularity in recent years, with an increasing trend towards their application in various fields, such as computer vision, natural language processing, and bioinformatics.

In this study, the protein expression of the Mg 2+ influx flow gene TRMP7 (transient receptor potential melastatin-subfamily member 7) and the Mg 2+ efflux-related gene S41A3 (solute carrier family 41 member 3) and CNNM1 (ancient conserved domain-containing protein 1) were significantly reduced with increasing doses of MgO NPs, while the transcription levels of the mitochondrial Mg 2+ inward flow transporter mrs2 (mitochondrial RNA splicing 2) showed an increasing trend followed by a significant reduction.

Regarding the microdroplet generation test with the nonfluorinated COC chip, the sizes of the generated microdroplets exhibited an increasing trend for a given oil-phase pressure as the water-phase pressure continuously increased.