“an observed trend”

[ 22 ] Although not statistically significant, there was an observed trend of increased HSA with advancing age among individuals classified at GMFCS level V.

There was an observed trend toward decreased incidence of VTE, though larger studies utilizing serial imaging to assess VTE will be required to confirm this benefit.

Although the National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study did not identify a significant difference in the beneficial effects of IV t-PA in patients with minor strokes compared to those who received a placebo, there was an observed trend suggesting that minor stroke patients who received IV t-PA experienced favorable outcomes [ 21 ].

Although the proportion of emergent operations did not show statistical differences between groups, there was an observed trend of an increasing percentage of emergent surgeries with the progression of surgical expertise.

With an observed trend of increasing fill rates over time, this ‘pipeline’ is set to expand in the future.

This finding is echoed by recent coroner’s reports showing an increased prevalence of stimulants in opioid overdoses [ 7 , 24 ], and is aligned with an observed trend of initiation of methamphetamine use by people who use opioids [ 30 ] and increases in methamphetamine-related emergency room admissions [ 31 ].

There was an observed trend toward an increased DFS event rate beyond 36 months compared with the previous 36 months in the osimertinib group; however, the benefit of osimertinib treatment is clearly maintained as the curves remain separated beyond the 3-year treatment period.

Furthermore, there was an observed trend of increasing positive correlations between adaptive immune subsets (CD8+ T cells and MAIT (mucosal-associated invariant T) cells) and the innate subsets (dendritic cells and natural killer cells) in lcSSc patients with PAH, as compared to those without PAH [ 38 ].

However, an observed trend indicated a decrease in the secondary attack rate with an increase in vaccinations among household members of confirmed BA.5 and BA.2.75 cases.

The reasons for early termination given by the DSMB are an observed trend towards futility for efficacy combined with safety concerns.

There was an observed trend towards a longer mOS in patients who switched from VEN + HMA to a VEN + HMA + IDHi triplet rather than a subsequent IDHi doublet or monotherapy (Supplemental Fig. 6 ).

An observed trend demonstrated increased mortality rates with elevated risk scores in the TCGA cohort of ccRCC patients ( Figures 2A-F ).

Each line segment, or ‘Joinpoint,’ represents an observed trend.

An observed trend suggests that grasses with the highest CP ( U. arrecta and L. hexandra ) promote greater DMD, ammonia and TVFA.

On the other hand, significantly higher levels of IL-6 in addition to an observed trend of higher expression of TNF-α measured after 6 days of in vitro stimulation of PBMC could support disruption of the blood–brain barrier and promote viral and immune cell influx into the CNS, leading to more severe disease in VBT TBE patients.

Although no statistical difference was found between low and high MDA, there is an observed trend for higher counts of Faecalibacterium prausnitzii in high-MDA mothers ( Figure 4 ).

There was an observed trend of phenotypic resistance against Norfloxacin, Ampicillin and Tetracycline among Gram‐negative bacteria (mostly Enterobacteria ).

In the male gender, there was an observed trend of increasing rates with age, although this trend was not evident in the female gender.

Results Analyses indicate that while rs907091 and rs1143770 may have potential associations with MetS susceptibility and an increased risk of atherosclerosis and diabetes, there is an observed trend suggesting that the rs1333045 CC genotype may be associated with a decreased risk of MetS.

Therefore, to determine whether the decrease in GNH was associated with the lockdown and the invasion specifically and not only an observed trend (since we control for the season, country and day-of-the-week, new COVID-19 cases per million as a proxy for the evolution of the pandemic and previous happiness levels), we consider the estimated coefficient of the interaction variable " lockdown i , c * Year i −1 or invasion i , c * Year i +1 ," i.e., the DiD estimator.

At a given UV intensity, an observed trend also showed a decrease in gelation time when the concentration of photo-curable monomers was increased.

Although we did not find a statistically significant reduction in mortality or risk of organ failure, an observed trend toward decreased mortality in the intervention group prompted further exploration.

An observed trend of improved functional outcomes in recipients of UCB after 5 days post stroke could be explored in future clinical trials.

While a small number of cases prevented statistical significance, there was an observed trend toward significance, with the preserved bone length being 2.1 cm longer in the reconstructed group.

This finding is in keeping with an observed trend toward increased use of digital health technology in older adults with chronic diseases [ 18 , 20 ].