Moreover, cells expressing this mutant form of LAT showed a statistically significant increase of proximal intracellular signals such as phosphorylation of LAT in tyrosine residues 171 and 191, and also enhanced ZAP70 phosphorylation approaching borderline statistical significance ( p = 0.051).
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However, the normal ferritin group showed a slightly higher mean choriocapillaris flow rate compared with the other groups, approaching borderline statistical significance ( p = 0.052).
However, the chi-square test for the differences in the last domain of childhood trauma (other major upheaval that may have shaped life or personality significantly) was approaching borderline statistical significance (χ 2 = 5.630, p = 0.060) with the lowest confiding (18.79) obtained for offenders with mental illness.
The result showed compounds 2 and 3 significantly increase and decrease Smad2/3 phosphorylation respectively ( Figure 6 B); the TGFβRI inhibitor showing a trend toward a decrease in Smad2/3 phosphorylation but approaching borderline statistical significance ( p = 0.08).
In patients with haemorrhagic lesions the risk for recurrence was lower, aRR = 0.17 (approaching borderline statistical significance p = 0.08).
After adjusting for confounders, significant positive associations were found between serum cotinine levels and rhinitis ever (adjusted odds ratio [AOR] = 2.95; 95% confidence interval [CI]: 1.15–7.60; P = 0.03) and current rhinitis (AOR = 2.71; 95% CI: 1.07–6.89; P = 0.04), while the association for physician-diagnosed rhinitis approaching borderline statistical significance (AOR = 2.26; 95% CI: 0.88–5.83; P = 0.09) ( Fig. 1a ).
However, the observed associations were generally modest in magnitude, and findings approaching borderline statistical significance should be interpreted with caution.
However, the OR for the association between sex and intrinsic capacity impairment was higher in individuals who were not financially independent than in those who were, approaching borderline statistical significance in Model 3 (OR [95 % CI]: 1.68 [0.96–2.96] and 0.97 [0.62–1.50]; P for interaction = 0.059).
A recent study reported that diffractive extended depth of focus IOLs showed statistically significantly better uncorrected visual acuity (VA) compared with monofocal control; however, these differences were modest at best (1–2 letters for manifest refractive spherical equivalents within 1.0 D between groups and approaching borderline statistical significance) and hence, it is difficult to conclusively report if they are clinically meaningful [ 93 ].
Compared to inseminating TMC > 20 million, inseminating TMC < 5 million was associated with a reduced pregnancy rate approaching borderline statistical significance (TMC < 5 million: RR = 0.61, 95% CI 0.36-1.03; TMC 5-20: RR = 0.96, 95% CI 0.69-1.33, adjusted for strict morphology).