Both methods showed negative associations between CLIC5 and CP, with the weighted median method achieving statistical significance (beta = −0.1561, SE = 0.07822, P = .04593) and the weighted mode method approaching significance (beta = −0.1728, SE = 0.1096, P = .1389; Table 1 and Fig. 1 ). 3.5.
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These effects were particularly strong when comparing safe trials [AV− and CS−; t (22) = 4.24, p < 0.0005], but also approaching significance when contrasting the aversive trials [AV+ and CS+; t (22) = 1.5, p = 0.14].
None of the glucose metabolism-related parameters was significantly different between the VDD and VDS groups in the current study, but differences in levels of some of them—glu120, ins0, and HOMA IR—were approaching significance (respectively: p = 0.14; p = 0.19; p = 0.18).
While group differences were non-significant at 18 months, average bone strength increased 2.4% from baseline in the 18-mo HiProt group (0.09 ± 0.11kN), increased 1.0% in the 6-mo HiProt group (0.03 ± 0.11kN), but decreased −0.6% in the RecProt group (−0.02 ± 0.10kN), with the RecProt versus 18-mo HiProt group comparison approaching significance ( p = 0.14; Table 2 ).
Although there were no other differences approaching significance, there were slight trends (less than .20) for ER Visits (p=.146) and health distress (p=.116).
The only correlations approaching significance are for pain (ρ = 0.058, p = 0.147) and general health (ρ = 0.067, p = 0.097), which are still not significant, suggesting that BMI does not have a strong or meaningful impact on these aspects of health (Table 5 ).
The increases in 38% SSI in the milk group and 66% SSI in the egg group were slightly less than those in the gelatin group, approaching significance with p value of 0.081 (Dunnett’s adjusted p = 0.148) and 0.057 (Dunnett’s adjusted p = 0.106), respectively.
Due to the preliminary nature of this study, and to provide rich data for future studies to explore further, we report results for potentially noteworthy findings which are tests that achieved statistical significance ( p -value ≤ 0.05), and tests where the fold change was >1 or the p -value was approaching significance (0.05 < p -value < 0.15).
The paired-samples t -tests, α = 0.01, with a mean difference of 0.565, 99% CI [0.017, 1.112], p = 0.008 for the ANN, 0.437, 99% CI [0.151, 0.722], p = 0.0003 for the LDA, 0.488, 99% CI [0.083, 0.892], p = 0.003 for the LIN-SVM, and 0.372, 99% CI [−0.111, 0.857], p = 0.040 for the RBF-SVM, all revealed significant differences or approached significance between the two approaches without any correction for multiple comparisons (noting that only the LDA result remained significant, p = 0.0012, after Bonferroni correction, with the ANN, p = 0.032, and the LIN-SVM, p = 0.012, approaching significance; the RBF-SVM, p = 0.16, would be considered not significant).
It is possible the small sample size made it difficult to detect significant effects (e.g., the model predicting the total performance score from total TA hours was significant before adjustment, approaching significance after adjustment, FDR p = .16).
0.832, p = 0.015), IDI (−2.59%, p = 0.003), and NRI (approaching significance, p = 0.160).
In complete or partial responders (CR/PR), lymph node tissue demonstrated the strongest negative correlation ( r =-1.00, p = 0.0833), approaching significance; the “other” tissue category also showed moderate negative correlation ( r =-0.657, p = 0.175).
We found a positive correlation approaching significance between sLF and MRT score (Pearson's = 0.342; p = 0.194; Figs. 2 and 3 ).
Variables approaching significance differences ( p < 0.2) between those readmitted and not readmitted within 30 days were included in a binary logistic regression analysis using a backwards Wald selection method to determine factors associated with being readmitted within 30 days of the index admission. 3.
Genetic variants identified as approaching significance (using the standard p<0.20 [ 17 ]) were characterized as having the potential to predict weight change, and were included with demographic characteristics in subsequent regression modelling for aim 2.
Variables at or approaching significance on univariate analysis (p<0.2) and clinically relevant variables were entered in the models.
Every univariate parameter reaching or approaching significance (p < 0.2) was then tested in a Cox multivariate model using the conditional backward method.
Variables that were statistically significant or approaching significance ( p -value < 0.30) were utilized to construct a multivariable logistic regression model.
These differences were not statistically significant, although were approaching significance in the high temperature (standard vs low: P=0.32, standard vs high: P=0.15).
The rate of blastocyst development between CRISPR injected embryos and non-injected controls was also not significantly different at day 5 or 6, but was approaching significance by day 7 of embryo culture ( p = 0.35, 0.08, 0.06, n = 566, 863, 859, 3 replicates, respectively).
The Friedman test showed that the differences among imputation methods were approaching significance ( p = 0.3539).
Following up on the interaction effects approaching significance, we could observe that the taVNS and sham group reported similar familiarity‐based memory, t (120) = −0.78, p = 0.43, but the taVNS group showed a recollection‐based memory advantage, t (120) = 2.3, p = 0.01.
Neither of the fixed factors nor their interaction were significant, with only Weather approaching significance: Contrast F (1, 197) = 0.61, p = 0.437; Weather F (1, 6,467) = 3.82, p = 0.051; Interaction F(1, 6,467) = 0.59, p = 0.441.
Line 154-155: “...and approaching significance for BF swimmers (P=0.53).”... this p-value is not approaching significance...missing zero?
Analyses using substantive attempt as the dependent/outcome variable returned no significant results except for finding Near Psychotic Somatization subscale score approaching significance as a negative predictor of substantive SA (beta=-0.241, p=0.55) when regressed with scores on Frantic Hopelessness and Ruminative flooding subscales.