“borderline significant”

[ 16 ] found that there was a borderline significant increased overall cancer risk conferred by rs2736098.

For ERBB2 tumors, the low expression of 5q33 (borderline significant; Fig. 3A ) and interleukin (IL)-12 ( Fig. 3E ) were associated with poor outcomes, which was in agreement with the GSEA meta-analysis.

In the BWHS cohort the relationship was borderline significant, whereas no evidence for a dose‐response relationship was reported in the Generation R and KoGES cohorts.

936, 95% CI: 0.913–0.958) worse initial physical function, and about an additional 0.5% (IRR = 0.995, 95% CI: 0.994–0.996) worsening every year compared to those without osteoarthritis, though this additional slowing was only borderline significant.

Support for Tobacco-free City Property Policies Current Smokers Among current smokers, females had higher odds of favoring tobacco-free city property policies compared to males (OR 1.58, CI 1.00–2.49), although the association was borderline significant.

To account for multiple testing, p-values ≤ 0.01 were considered as significant and p-values >0.01 and ≤ 0.05 were considered as borderline significant.

While sex, age, and bifurcation type were significant predictors and syntax score was a borderline significant predictor for long-term mortality, procedural aspects, such as POT or KBI, did not influence the outcomes.

In addition, EBV DNA copy numbers were positively correlated to sCD27 in serum at baseline in patients with measurable EBV DNA copy number (borderline significant), which might be attributed to the fact that an EBV infection triggers CD70 expression which, in turn, increases activity of CD27‐CD70 axis. 8 Interestingly, this correlation was absent following the first two administrations of cusatuzumab.

In a similar analysis of breast cancer risk involving nearly 50,000 cases, vitamin B6 levels were borderline significant in estrogen/progesterone receptor-negative tumors but not ER/PR + tumors [ 44 ].

The research leads to the result that the use of plan-do-study-act (PDSA) led to a borderline significant reduction of 65.4 minutes in waiting time over 6 weeks and an insignificant improvement in satisfaction, suggesting that quality improvement efforts have to be maintained over a considerable period to be able to produce significant changes.

Same findings were found in multivariate analyses but became borderline significant (all had confidence intervals that narrowly include the null value).

In the group of children with CI, AF was strongly positively associated with SF and FF, while the association with PF was borderline significant.

Targeted surgical and medical treatment of PA-induced LVM via LV inward remodeling and ADX contributed to a prominent and persistent decrease in LVMI, while medical treatment resulted in a borderline significant fall ( 101 ).

However, in some comparisons, there were borderline significant results that need to be clarified in further large studies that have sufficient power to detect the statistical difference between groups.

The CKD-EPI cr had a value of 54.79 mL/min which borderline significant and the other equations had significant differences compared with CrCl ( Table 2 ).

Four of the 5 SNPs were also significant, and one was borderline significant in the Singapore cohort.

Altered methylation was also observed in glutamate ionotropic receptor NMDA type subunit 1 ( GRIN1 ; rho = − 0.28, p = 0.059) and synaptic Ras GTPase activating protein 1 ( SNYGAP1 ; rho = 0.26, p = 0.079), although borderline significant with spearman correlations (Fig. 5 B).

For these types of datasets, the best-fitting model has a borderline significant P -value, the second best-fitting model has a highly significant P -value (and is very close in terms of A I C c ), and the model-averaging approach arrives at a significant P -value.

However, when combining the effects of the different doses, the vertebral fracture reduction remained borderline significant, while significance was lost for the non-vertebral fracture reduction [ 199 ].

Similarily, adjustment for HbA1c on top of conventional risk factors showed that the association between copeptin and the primary end point as well as its components CAD and HF remained significant or borderline significant, whereas the association between copeptin and death disappeared ( Table II ).

Only 3 (miR99a, miR125b-2* and let7a) of them did show statistically significant associations with p-values (p = 0.05) close to become borderline significant and partly calculated based on an even smaller sample size than 5 (n = 3) in the group of occult metastasized seminoma.

Similarly, the WHI study observed a borderline significant association between CEE monotherapy and any arthroplasty (HR, 0.84; 95% CI, 0.70–1.00).

A stronger, borderline significant association was seen in cohort studies.

Hypertension and aggressive PCa Summary Hypertension demonstrated a borderline significant association with aggressive PCa, with moderate heterogeneity.

Furthermore, the lack of FDR correction for multiple comparisons might increase the risk of Type I errors, especially for borderline significant results.