Barely Significant
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close to significance

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In the literature

close to significancep = 0.0571.1× alpha
At the same time, MYO was significantly more present in individuals with the presence of at least one R allele in the recessive model ( p = 0.019/ES = 0.409) but only close to significance in the genotype model ( p = 0.057/ES = 0.129).
close to significancep = 0.0581.2× alpha
Specifically, the subgroups analysis showed that the effect size for the 8 studies that used delayed intake was significant ( g = 0.30, 95% CI: [0.08–0.53], p = 0.008) while the average effect size for the 21 studies that used immediate intake was close to significance, ( g = 0.10, 95% CI: [0.00–0.20], p = 0.058).
close to significancep = 0.0581.2× alpha
Living in a rural/small town (reference: urban) was marginally significant (ß = −0.872, 95% CI = −1.750 to 0.006, p = 0.052), and the impact of religious affiliation, specifically belonging to other religions (reference: none/agnostic/atheist), remained close to significance (ß = 3.388, 95% CI = −0.120 to 6.897, p = 0.058).
close to significancep = 0.05871.2× alpha
When the recipient groups were compared, those that received Neumifil had consistently lower clinical scores than those receiving the vehicle ( Figure 2 c), reaching significance 7.4 days post-challenge ( p = 0.0117) and close to significance at 9 days post-challenge ( p = 0.0587).