Barely Significant
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did not reach statistical significance

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In the univariate analysis, classical risk factors showed variable associations; hypertension showed a trend toward significance (p=0.06), while diabetes (p=1.00), atrial fibrillation (p=1.00), and previous stroke (p=0.39) did not reach statistical significance as individual predictors.
a decreasing trendp = 0.061.2× alphagold
did not reach statistical significancep = 0.061.2× alphaplainly factual
In contrast, the expression level of arginase-1, an M2-type microglial marker, was significantly reduced in OBX mice, while TGF-β exhibited a decreasing trend that did not reach statistical significance ( p = 0.06; Fig. 4 J and K).
did not reach statistical significancep = 0.061.2× alphaplainly factual
showed a trendp = 0.061.2× alpha
Assessment of hepatic triglyceride levels confirmed that HFD-fed mice had significantly higher liver triglycerides compared to Chow-fed mice ( Fig 4B ) (p < 0.01) but HCD-fed mice only showed a trend towards higher liver triglyceride content, which did not reach statistical significance (p = 0.06).
The number of osteomyelitis-related hospitalizations showed a marginally significant positive association ( β = 0.237, OR = 1.268, 95%CI: 0.990 ~ 1.623, p = 0.060), suggesting that increased hospitalizations might contribute to attitude formation, though it did not reach statistical significance.
did not reach statistical significancep = 0.061.2× alphaplainly factual
showed a trendp = 0.061.2× alpha
Although patients with NLR ≥ 2.5 showed a trend toward more frequent postoperative complications (59.8%) compared to the NLR < 2.5 group (40.2%), this difference did not reach statistical significance ( p = 0.06).
did not reach statistical significancep = 0.061.2× alphaplainly factual
showed a trendp = 0.061.2× alpha
The overall pooled estimate across both time points showed a trend toward improvement that did not reach statistical significance (mean difference: 21.27, 95% CI: −0.96 to 43.50, p = 0.06), with substantial heterogeneity observed ( I 2 = 80%, p = 0.03).