Correlation of IDH1/2 mutation with CPEB1 methylation was highly significant (Fisher's two-sided exact test, p < 0.001).
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Highly significant positive correlations were observed between IQ percentile and mid-year Arabic language scores and Arithmetic scores (P < 0.001), and significant negative correlations with the total score of PSCL and its subscale scores (externalising, inattention, and internalising behaviour) (P < 0.001) among the students.
All values except the among-site category in the AFLP analysis ( p < 0.05) revealed highly significant differences at p < 0.001.
Group differences were considered highly significant, significant, and almost significant when the probabilities (p) of error in rejecting the null hypothesis were p < 0.001, p < 0.01, and p < 0.05, respectively.
The correlation between fold changes of expressions of these 17 validated miRNAs between discovery and second validation data sets was highly significant ( r =0.90, P <0.001; Supplementary Figure S1B ).
Another highly significant ( P < 0.001) negative correlation was found between the patient's knowledge about glaucoma as a disease and its possible sequelae and the delay in years.
Our F -test result was highly significant, demonstrating substantial differences in symmetry between surface and three cavefish populations ( F (3,116) = 23.99, P << 0.001).
By contrast, a 2 × 5 (Sotos/Sibs × SRS subscale) mixed measures ANOVA found a highly significant main effect of group, ( F (1,163) = 474.88, p < .001) as scores for the children with Sotos syndrome were considerably higher than for the unaffected siblings.
The median OS for the four risk categories was not reached, 240, 72 and 18 months, respectively, and the difference was highly significant ( P <0.001; Figure 1 ).
2c ) indicated that improvements were highly significant in the EXPECT ( P < 0.001) and the SUPPORT group ( P < 0.01), but not after SMC.
In addition, neural survival is compromised due to inhibition of nerve growth factor (NGF) transcription [ 33 ] and a highly significant correlation between the decrease in circulating levels of NGF and the severity of CIPN has been reported ( P < 0.001) [ 34 ].
The results were considered significant when p (degree of significance) is less than 0.05, very significant when p < 0.01 and highly significant when p < 0.001.
All risk factors yielded highly significant ( p < 0.001) differences across all of the demographic variables with the exception of poor diet by marital status ( p = 0.527), probably due to the large sample size in the case where difference were small (i.e., less than 3%).
The differences between the clinics were highly significant ( p < 0.001) (Table 2 ); 7.6% of patients seen in the ODM had a previous suicide attempt.
2 ). The differences among the zones were highly significant ( F (2,15) = 11.95, p < 0.001).
Differences of [ 11 C]PiB binding and sCBF measures between AD and HC both were highly significant ( p < 0.001).
Resolution of population structure and migration Pairwise F st estimates (Table 2 ) were highly significant ( p < 0.001) for all population comparisons, with the exception of the two Tanzanian sites (0.0007), and PNG with the Solomon Islands (0.0059).
In addition, Bartlett's test of sphericity was found highly significant ( P < 0.001).
Statistical significance was defined as P < 0.05 and highly significant when P < 0.001.
The full RSM model was highly significant ( P < 0.001) and explained a very large proportion of the variation in misfit between the empirical data and our MC simulations ( R 2 = 0.69).
A significant difference (P <0.10) was obtained between the original analysis (mean = 0.40 cmol c /kg) and reanalysis (mean = 0.33 cmol c /kg), although linear regression showed a highly significant linear relationship between the two data sets (P <0.001; R 2 = 0.99).
Cells were considered to have space-time structure when both factors as well as their interaction were highly significant (p<0.001).
The Kaiser-Meyer-Olkin measure of sampling adequacy was 0.71, above the recommended value of 0.60 [ 127 – 129 ], and the Bartlett test of sphericity was highly significant (1852.64, p < 0.001), indicating that PCA is appropriate for this dataset [ 114 – 116 , 118 , 130 ].
All evaluated visual, refractive, and aberrometric parameters demonstrated highly significant improvement in both studied groups (all P < 0.001).
This resulted in a highly significant reduction of malignant cell survival, from 69% (the survival rate for the control cells) to 39% (P <0.001).