“highly significant”

The association between overall mortality and increasing age remained highly significant when adjusted for underlying co-morbidities or immunosuppression (p = 0.001).

The frequencies of the mutant genotype AA and A allele carriers of Bcl-2 -938C > A polymorphism were approximately 4 and 2.5-fold higher in endometriosis compared to the control women, which were highly significant (p > 0.001).

However, SNP-SNP interaction analysis with the previously identified disease-associated SNP rs2236225 G→A (R653Q polymorphism) in the MTHFD1 gene revealed a highly significant association with NTD risk in both case and maternal groups (P < 0.001 and 0.01, respectively).

Data were statistically analysed following ANOVA one way or two way test, followed by the post-hoc Tukey test, with differences considered significant ( p < 0.05, * or lowercase letter), very significant ( p < 0.01, ** or bold lowercase letter), highly significant ( p < 0.001, *** or capital letter) or very highly significant ( p < 0.0001, **** or bold capital letter).

Our data displayed a highly significant difference in alpha diversity between the groups (p<0.001) and a significantly higher dominance in the diseased samples versus healthy samples (p<0.001) (Figs 5 and 6 ).

Population expansion was also supported by highly significant negative values of both Tajima’s D (−2.7186, P < 0.001 in COI; −2.7292, P < 0.001 in mtDNA) and Fu’s F S (−28.5901, P < 0.001 in COI; −28.6235, P < 0.001 in mtDNA) tests.

Furthermore, the overall contributions (main and interaction effect) of both "jacked up" and "barriers to health or harm reduction services" to the final model were highly significant ( p < 0.001 for both variables).

* p < 0.05 was considered significant, ** p < 0.01 was considered highly significant, and *** p < 0.001 was considered very highly significant. 3.

Chest Pain Type stood out as the most influential categorical feature, contributing 14.8% to the model, supported by a highly significant chi-square statistic of 15.78 (p < 0.001), reflecting its well-established clinical role in diagnosing cardiovascular conditions.

Differences were determined to be statistically significant at p < 0.05 and highly significant at p < 0.001.

The quantitative data confirmed the previous qualitative observation in revealing a highly significant increased incidence of Type 1 cells in Cyfip1 +/− (LME: χ 2 (1) = 68.49, p < 0.001, Fig. 4c ).

When stratifying into the two age groups, the relationship between HV and memory was not statistically significant in the younger group (p = 0.066), but in the older group there was a highly significant relationship when controlling for demographic variables (β = 0.40; p < 0.001; Figs 1B and 2A , Suppl.

Both aspiration and penetration were highly significant predictors ( p < 0.001) for the need of postoperative gastrostomy tube and return to a normal diet, as shown in Table 6 .

There was a highly significant correlation between membrane capacitance and NAS sensitivity of the eEPSCs in the SON neurons (correlation coefficient = 0.8, n = 19, p < 0.001; Fig. 5 ).

When all kidneys were evaluated together Pearson's correlation coefficient between skGFR and any stereological parameter was above 0.60 and highly significant (p < 0.001), and with r-values ranging from 0.62 regarding number of glomeruli, to 0.78 regarding cortical volume.

Strong positive and highly significant correlations were observed between C-terminal and N-terminal PvCSP-VK210 antigens at all timepoints: day 0 (ρ = 0.85, p <0.001), day 90 (ρ = 0.76, p <0.001), day 270 (ρ = 0.75, p <0.001) and day 360 (ρ = 0.9, p <0.001).

The Kaiser–Meyer–Olkin (KMO) measure of sampling adequacy showed the data for Section 1 to be factorable (KMO = 0.856), Bartlett’s test of sphericity was also highly significant (χ 2 = 2868, df = 36, p < 0.001).

In five topics, C1, C2, C4, C8, and C10, there was a highly significant difference ( p < 0.001) between the studied and non-studied the nutrition course groups.

Highly significant differences were observed between the change in LSaBMD z-scores between the placebo and risedronate groups; 0.274, (95% CI 0.061, 0.487; p < 0.001) and between the risedronate and the alfacalcidol groups; 0.326 (95% CI 0.109, 0.543; p < 0.001) but not between the placebo and alfacalcidol groups; − 0.052 (− 0.257, 0.153).

Additionally, a highly significant association between high levels of FBP1 and high tumor cell proliferation rate (Ki-67) (p = 0.001) was noted.

SNP Numbers, Coverage, and Correlations The mean number of sequencing reads (mean ± 1 S.D.) generated per individual from tissue samples (1,608,863 ± 307,130) was 2.1× more than the number of reads generated from swab samples (518,985 ± 238,072), and this was a highly significant difference ( Table S2 ; t = 9.693, p < 0.001).

In the medial TH, one-way ANOVA indicated a highly significant effect of circadian time on neuronal activation (F 6,23 = 8.47, p < 0.001).

This increase was highly significant ( p < 0.001) in seven out of eight pairs.

The individual telomere attrition rate was inversely correlated with initial TL at a highly significant level (r = –0.752, P <0.001), indicating that the attrition rate was most pronounced in individuals with long telomeres at baseline.

Strikingly, all 41 IFN-responsive target genes are induced to a higher level in the keratinocytes harbouring higher Wnt5a levels, corresponding to a statistically highly significant 1.8±1.1-fold relative hyper-induction across all target genes (p = 0.001).