“highly significant”

HMGCR, although not listed as top five key drivers, was a highly significant key driver ( P < 10 −14 ).

all β m being equal), which led to a highly significant deterioration of the likelihood function ( P value <10 −14 ).

For the two metrics, the difference in performance is highly significant between each pair of models (p < 10 −14 ).

This analysis confirmed that human observers exhibited much lower SSNR thresholds than DNNs, outperforming the DNNs by a highly significant margin at recognizing objects in pixelated noise ( t (26) = 15.94, p < 10 −14 ); they also outperformed DNNs at recognizing objects in Fourier phase-scrambled noise ( t (26) = 12.29, p < 10 −11 ).

2 B, the time required to curate each case demonstrates a leftward shift in the distribution for S-BCAW relative to MICAW, with a highly significant difference ( p = 1.07E-14).

We detected a small but highly significant association between the anhedonia PRS and the anhedonia phenotype scores (β = 0.0007, p = 1.17 × 10 –14 ).

The enrichment of expressed genes in the set of active promoters was highly significant ( P = 1.2 × 10 −14 ).

Highly significant differences were detected between calculations using Phylomatic and the unconstrained (t = -9.7575, df = 69, p-value = 1.271e-14; t = -14.686, Barocode only: df = 67, p-value < 2.2e-16), as well as the constrained (t = -12.365, df = 69, p-value < 2.2e-16; Barcode only: t = -17.857, df = 67, p-value < 2.2e-16) barcoding ML analyses ( Fig 5 ).

At α = 0.05, there were highly significant differences among the predicted genotypic effects ( P = 1.33e-14) when compared to the population mean (μ) (Supplementary Table 2 ).

The omnibus ANOVA demonstrated highly significant differences between groups (F = 32.52, p = 1.36 × 10 −14 ), confirming that complexity scores correspond to measurable differences in clinical effort and resource utilization ( Table 4 ).

After 24 hours, we quantified luciferase activity and found a highly significant effect of group (One-way ANOVA, F = 169.95; df = 4; p = 1.37 10 −14 , Figure 4 B).

For sites within genes, MLV showed a highly significant bias in favor of integration near transcription start sites ( p = 1.4 × 10 −14 ).

Despite these conservative summaries, paired Wilcoxon signed-rank tests on the encounter-level differences demonstrated highly significant separation: median ΔP_event for censored levels exceeded that for onset levels (p ≈ 1.4 × 10 −14 ), and median W_event for censored levels similarly exceeded onset W_event (p ≈ 3.1 × 10 −11 ).

Comparative analysis of the paired samples revealed highly significant overexpression of NDC80 mRNA in ccRCC samples from TCGA (p = 1.4e-14) and ICGC (p = 1.2e-11) ( Figures 2 B and 2C).

The results indicated a highly significant slower pace of potentially functional mutations ( P = 1.42 × 10 −14 ) ( Fig. 3 ).

When comparing measurements from two observers, they exhibited a highly significant correlation coefficient (r = 0.98, p = 0.143 × 10 −13 ).

Acquisitions of 14.5 min duration performed on anesthetized, spontaneously respiring animals, without gating and administration of contrast agent resulted in a highly significant correlation (R = 0.98, p = 1.5 × 10 −14 ) between the MRI-derived liver volumes and the post-mortem liver weights in hepatectomized, untreated mice. 1,4-bis [2-(3, 5-dichloropyridyloxy)] benzene (TCPOBOP), a synthetic agonist of the mouse constitutive androstane receptor and a potent activator of cytochrome P450 monooxygenase activity ( Halwachs et al., 2007 ) shown earlier to induce hepatocyte proliferation and hepatomegaly ( Ledda-Columbano et al., 2000 ), was then evaluated as test compound in the model.

This contribution was highly significant ( p = 1.5 × 10 −14 , F -test).

The correlation of the probability estimates of the models from the hippocampus and frontal cortex was highly significant and of moderate strength ( ρ = 0.41, p = 1.5e−14; Additional file 1 : Fig.

Their p values according to the GTEx data by the same selective expression measure (the proposed robust-regression z -score) were also highly significant based on the transcript-level selective expression, p = 1.5E−14 and 9.4E−12, respectively.

The most associated SNP, AX_91849634, was found on chromosome 3 with a highly significant p -value of ≤1.53 × 10 −14 .

Consistent identification of TGs across both sub-regions was observed, supported by highly significant overlaps for both upregulated (Hypergeometric test p = 1.6e-14) and downregulated ( p = 5.0e-17) genes, thereby underscoring the robustness of SCILD’s inference (Fig. 6i , Supplementary Table 3 ).

A highly significant relationship ( p = 1.61 × 10 −14 / p = 0.00, Table 6 ) was found between the P. minimum abundance estimates derived from amplicon sequencing data and the P. minimum -specific qPCR, while the relationships between microscope counts and qPCR and microscope counts and amplicon sequencing were not significant ( p > 0.05, Table 6 ).

Gene-based association analysis revealed a highly significant overlap between the two studies, with 15 shared genes among the 61 genes identified as significant in our GWAS (Supplementary Data 3 ; hypergeometric test P = 1.63 × 10 −14 ).

In contrast, the correlation between CD4 + and CD8 + T cell responses was highly significant in aggregate (R = 0.6756; p = 1.70 × 10 −14 ; Figure 2 F) and was significant for each of the individual antigen comparisons ( Figures 2 G–2I).