When data from all three groups were pooled, highly significant correlations (all p < 0.001) were confirmed across the spectrum of BA volumes: larger volume was associated with lower intra-aneurysmal velocity ( r = −0.821) and TAWSS ( r = −0.866), and higher OSI ( r = 0.901) and RRT ( r = 0.939).
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These differences are robust across different age comparisons, with particularly strong effects observed in the transitions to ages 14 and 15, where the decrease in overlap compared to earlier ages consistently shows large effect sizes [HLe’s >3.0 (lower 95% CI >2.5)] and highly significant differences [all MWU p values <0.001].
3 of the 4 GO terms that showed highly significant enrichment ( p <0.001) were associated with ion homeostasis ( Supplementary Table 1 ).
At the group level, a highly significant negative association was observed ( ρ = −1.0, p < 0.001), indicating that Chinese listeners performed more poorly as overlap scores increased.
A highly significant positive correlation was found between the two datasets ( p < 0.001, Figure 6 ), confirming the accuracy and reproducibility of our transcriptomic profiling. 4.
In addition to the significance value ( p < 0.05, *significant; p < 0.01; strong significant; p < 0.001, highly significant), the effect sizes for all ANCOVAs are given using Partial Eta Squared (ɳ 2 p ). 2.5.5.
At T 2 , a highly significant drop was observed ( p < 0.001), with a mean value of 10963 Hz.
3 ), with highly significant positive correlation across sites ( r = 0.77; P < 0.001) and time of sowing ( r = 0.73; P < 0.001).
Statistically highly significant data, with a p -value < 0.001 and <0.0001, are marked by *** and ****, respectively. 3.
The PUL scale showed highly significant loss of function at 12 months (p<0.001), with a mean drop in score of 9.2 (95% CI -11.9; -6.4) out of 74; this numerical result was predominantly driven by the loss of function in the shoulder domain.
Exposed workers showed neither clinical signs of immunosuppression nor alterations in total leukocyte or leukocyte subpopulations, while significant differences (p<0.05) were demonstrated for IL-12p70 and highly significant differences (p<0.001) for IFN-γ, IL-2 and IL-8 levels.
A highly significant increase (p < 0.001) of angiotensin I (Ang I) was observed in ACE2 KO mice, which was accompanied by elevated concentrations of its downstream metabolites including Ang II (p = 0.027) and Ang-(1-7) (p = 0.023) ( Fig. 1a ).
Notably, SOFA and APACHE II themselves did not reach independent significance in multivariable analysis ( p = 0.737 and p = 0.470, respectively), whereas NT-proBNP remained a highly significant predictor ( p < 0.001), suggesting that it captures a dimension of cardiopulmonary vulnerability not adequately reflected by general severity-of-illness scores alone.
Results The results of the internal consistency analysis demonstrated good relationships between the items; Cronbach’s alpha coefficients for the four subscales were highly significant (p<0.001) (0.88-0.91).
Also, a closer scrutiny of the Cochrane review revealed that despite a highly significant ( p <0.001) moderate pooled odds ratio (OR = 1.45) in favour of pre-contact, heterogeneity of study populations, reported odds ratios, and types of questionnaires in the studies included in the meta analysis was substantial.
These large effect sizes, combined with highly significant p -values ( p < 0.001), demonstrate that the treatment effects are biologically meaningful and detectable despite the limited sample size.
When the average (instead of the best) values are considered, the relationships between the power generated by thrust force (Pt) and the power needed to overcome drag force (Pd A : active and Pd P : passive) are still highly significant: Pd P = 38.69 + 0.618 Pt, R 2 = 0.942, N = 10, p < 0.001; Pd A = 58.04 + 0.926 Pt, R 2 = 0.942, N = 10, p < 0.001.
When blood biomarker ratios were compared between the KOA and control groups, highly significant differences ( p < 0.001) were detected for activin A/FSTL1, and follistatin/FSTL1.
euphratica seedlings showed highly significant positive correlations with vascular bundle structure and midrib thickness (r = 0.63~0.91, p < 0.001), while soluble sugar content exhibited a highly significant negative correlation with vascular bundle structure (r = −0.74~−0.80, p < 0.001).
All F ST were highly significant ( P < 0.001).
Similarly, for every standard deviation increase in proactive personality, career calling rises by approximately 0.633 standard deviations, with this effect being highly significant ( p < 0.001), thus indicating that proactive personality is a key factor in career calling and supporting Hypothesis 4.
This was highly significant and, of all parameters assessed, the presence of TTR amyloid had the highest hazard ratio for death (HR 9.4 [2.4-35.6], p = 0.001, univariable Cox regression analysis).
Component 2 displayed a biologically plausible HDR, and a highly significant main effects Time, F (19, 874) = 84.31, P < .001, η p 2 = .65, clearly meeting the requirement of temporal validity.
Statistical analysis revealed a highly significant effect of light phase (χ 2 = 56.81, p < 0.001), whereas no significant main effect of treatment was detected (χ 2 = 0.68, p = 0.71), nor was a significant treatment × light interaction observed (χ 2 = 10.25, p = 0.115).
The level of significance was set as P-value ≤ 0.05 considered significant (*), P-value ≤ 0.01 considered highly significant (**), P-value ≤ 0.001 (***) considered highly significant.