“highly significant”

Similar negative correlations are observed for the rate of nonadaptive evolution (Δvolume: r =−0.545, P < 0.001; Δpolarity: r =−0.170, P < 0.001); these correlations remain highly significant ( P < 0.001 in both cases) even if the four datapoints in the top left-hand corner are removed.

Fisher’s exact test based on the concatenated Cytb and CR datasets obtained a highly significant ( P <0.001) relationship between genetic variation sites and lineage.

Our tabulated prediction accuracy (averaged over 39 subjects completing the experiment) over the full stimulus set (see Table 1 ) was highly significant for both valence (p < .001; signed rank; α = .05; h 0 : μ = .5) and arousal (p < .001; signed rank; α = .05; h 0 : μ = .5).

Moreover, the lag coefficients of both SLM and SEM, namely Lambda and Rho, were highly significant (P < 0.001) ( Table 3 ).

In contrast, the analysis revealed a highly significant reduction in pain with repeated LIPUS treatments (within-subjects effects, P=0.001).

Values of P < 0.05 (*) were regarded as statistically significant, values of P < 0.01 (**) as highly significant, and values of P < 0.001 (***) as most significant.

Aldo infusion for 4 weeks also resulted in signs of systemic inflammation, with increases in serum levels of the chemokine RANTES (regulated and normal T cell secreted; 1.6±0.1‐fold; Figure 3 B), a nonsignificant trend toward increased MCP1 levels (monocyte chemotactic protein‐1; 1.8±0.3‐fold, P =0.06), and a highly significant increase in spleen size (1.52±0.06‐fold increase in spleen weight/body weight; P <0.001; Figure 3 C).

This association was statistically highly significant ( P -value < 0.001).

The consumption of foods not recommended for diabetics was highly significant in rural rather than urban subjects p<0.001, in subjects with poor glycaemic control (HbAc1>7%) rather than good p<0.001.

Changes in performance Improvements in mean power (W/kg) were highly significant ( P < 0.001) for both boys ( Table 4 ) and girls ( Table 5 ) expressed in absolute terms and in percent.

The Friedman test indicated highly significant differences between DeepSeek-R1 and both OpenAI o1 (p < 0.001) and Grok3 (p < 0.001), with no significant difference between OpenAI o1 and Grok3 (p = 1.000)( Figure 2a ).

We also compared patient-derived MSRS composite scores with physician-derived clinical scales; while the correlations were weaker, these remained highly significant (p<0.001): EDSS (r s = 0.609), T25FW (r s = 0.497), and AI (r s = 0.591).

The effect of time was highly significant across all language measures (all P < .001), indicating continuous recovery over time.

A highly significant positive correlation ( r 6 = 0.98, p < .001) was found between CBD concentrations in homogenized brain tissue and the 5 CBD doses ( Figure 1A ).

Results During the lockdown, calls from private citizens showed a highly significant increase (+ 11.5%, p < .001) and occupational exposures decreased (− 11.7%, p = .011).

Overall, the menopause specific QoL score was higher for those who did not use lifestyle modification as compared to those who used lifestyle modification and the difference was found to be highly significant ( P < 0.001).

There were highly significant negative correlations between serum Mg levels and HbA1c, fasting glucose, and insulin resistance with (r = -0.969, -0.894, -0.653) respectively, p-value < 0.001.

A highly significant trend for increased glioblastoma and meningioma tumors rates with advancing age at diagnosis was apparent ( P < 0.001).

Differences between groups were considered significant if * p < 0.05, highly significant if ** p < 0.01 and extremely significant if *** p < 0.001.

Both sex and age of the child are highly significant with the prevalence of ARI ( p -value < 0.001).

Analysis of variance for each compound between and within each season showed highly significant differences between days and seasons (Friedman ANOVA, P < 0.001, Additional file 1 : Table S1 and Wilcoxon Matched Pairs Test, P < 0.0001, Additional file 1 : Table S2).

Two weeks after the booster immunization, the serum antibody titer of the mice in the 10 μg RBD-Alum-CpG group was 5.12 × 10 6 , the serum antibody titer of the mice in the 2.5 μg RBD-Alum-CpG group was 1.08 × 10 6 , and the serum antibody titer of the mice in the 10 μg RBD-Alum group was 1.06 × 10 4 , and the difference in the antibody titers between the three groups was highly significant ( P < 0.001 ) ( Fig. 2 c–e).

Because our initial analyses revealed highly significant ( P <0.001) genotype x environment (G×E) interactions (data not shown), all subsequent analyses were performed separately by location.

Statistically, there was a highly significant increase in the percentage of degenerated neurons in the VaD group compared with the control group (38.85 ± 2.71 vs. 1.75 ± 0.20, respectively, P < 0.001).

Both reductions were highly significant compared with preoperative values (p < 0.001) ( Table 2 ).