Significance testing for fixed effects in the mixed model ( Table 3 ) revealed that location effects were highly significant (P< 0.001).
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These values showed a highly significant difference in epidermal thickness (Kruskal-Wallis test, χ 2 = 78.944, df = 4, p < 0.001; Fig. 4 A).
Similarly, there was a highly significant difference in the time until the next fever spike (F (2,131)=15.66, p<0.001).
Statistical analyses were performed using a two-tail Fisher-exact test: P -values ≤ 5.00e-2 (a = 0.05) were taken to be significant (1.00e-2 ≤ P ≤ 5.00e-2 * significant; 1.00e-3 ≤ P ≤ 1.00e-2 ** very significant; P < 1.00e-3 *** highly significant).
In case of six measurements— IMaF, PMaF, SMaC, IMaC, BMaC and IMeF, the gender differences were found to be very highly significant ( P < 0.001).
2019 was 39% for consultations (from 37,590 to 22,908) and 49% for new referrals (from 4,490 to 2,271), with a highly significant median difference for both ( p < 0.001) ( Fig. 4 A,B).
The KMO coefficient was found to be 0.87, the chi-square value for Bartlett's test was highly significant (p < .001), and the data were suitable and sufficient for the factor analysis.
Plasma pTau217 showed a strong correlation with Aβ uptake ( r = 0.76) and a moderate correlation with tau uptake ( r = 0.61), both highly significant ( P < 0.001) (Supplementary Fig. 2 A).
This difference was highly significant ( P < 0.001).
We observed a highly significant reduction (P=0.001) at 30 μM ( Fig .1B ).
ANOVA showed highly significant (P < 0.001) effects of genotype on shoot, root, total dry weight and height, and significant (P < 0.05) effects of genotype × PGPR interaction on shoot and total dry weight both in flacca and sitiens plants (Table 2 ).
Results The mean serum cortisol level of the MPDS group showed a highly significant difference ( p < 0.001) from the controls.
The difference between the 2 groups for anti-HAV IgM positivity was highly significant ( P < .001).
Analyses performed with mechanical dispersion normalised to the RR interval yielded results consistent with those obtained using absolute time values, with differences between ATTR CA and control groups remaining highly significant ( p < 0.001).
Differences in age, gender, and hours in direct patient care were highly significant (p < 0.001).
The mean HDRS score showed a highly significant difference between the two groups ( p < .001).
There was a highly significant increase in the number of lymphocytes in group II compared to the control group (group I) (p<0.001).
The most striking and highly significant difference referred to the quantitative measurement of epidermal hyperplasia ( p < 0.001).
Warming by 4°C resulted in a highly significant reduction in CI from 4.1±0.19 to 2.9±0.17 in mussels held at ambient pH (p<0.001).
The mean total sperm motility and grade A progressive motility (before treatment: 44.8%±15.75% and 21.9%±13.13%, respectively) exhibited highly significant improvement ( p <0.001) following treatment with DAAs (after treatment: total motility, 52.56%±13.92%; grade A progressive motility, 29.2%±12.75%).
The LLM also correctly identified the highly significant difference between these molecularly defined subgroups via log-rank testing ( P <.001).
Highly significant (p < 0.001) differences were noted in most of maternal serum lipids in the patients group except changes in LDL-cholesterol, mean levels of total cholesterol and APO-B100 when compared with the control group.
The effect of the percentage of COVID-19-positive admissions per total admissions each week was also highly significant ( P < 0.001), DDDs per admission increasing by 0.32 (95% CI: 0.29–0.34) with each 1% increase in COVID-19-positive admissions, which ranged between 0% and 5% for most trusts in most weeks (Figure S4 ).
A highly significant reduction in dry weight in the complete and partial fasting groups ( P < 0.001 for both) was noted, unlike the non-fasting group, where no significant weight changes were noted ( P = 0.75).
Oral steroid group showed significantly higher complications (21.5 ± 8.83) compared with oral steroid and ITID group which as (2.63 ± 1.41) with statistically highly significant difference (P < 0.001) in comparison between the two groups ( Table 4 ).