“highly significant”

Comparison of CC and ML amplitude of displacement at the 4–12 h period versus 168 h period ( Table 2 ) identified a highly significant difference between the 4–12 h and 168 h timepoints for ML amplitude ( p = 0.005).

An increase in vacuolation over control was observed in every low-chloride buffer by every parameter, although the differences were statistically highly significant (p < 0.005) only in methyl sulfate, nitrate and gluconate buffers (Fig. 3 A), but not in the aspartate buffer.

Only variables with highly significant coefficients (adjusted P < 0.005) were included in the final model.

In presymptomatic individuals, a highly significant negative correlation between time to onset and repeat length ( r = −0.48; p = 0.005) was found.

cytoprotective or pro-inflammatory), differences from baseline were highly significant at the 95% confidence level by ANOVA (F 1,52 = 8.82, p < 0.005 for cytoprotective genes and F 1,46 = 9.25, p < 0.004 for pro-inflammatory genes) (Fig. 6c ).

Improved mean BOP, PPD, and CAL differences were highly significant ( P < 0.005) for the test group at the 6 th week.

Median chitotriosidase values showed highly significant commensurate reduction with eliglustat treatment in both cohorts ( P ≤ .005): 24% in non‐splenectomized switch patients and 38% in splenectomized switch patients after 2 years in this real‐world cohort compared to 63% after 4 years in ENCORE. 20 The safety of daily oral eliglustat cannot be assessed in the Registry, because adverse event data and reasons for discontinuing treatment are not captured.

Analysis of specific transcripts showed that this was driven by one of its two protein-coding transcripts, ENST00000517894, which showed a highly significant difference (p = 0.005) and a 2-fold higher expression in the presence of the risk allele.

A total of 17 SNPs that were associated with adaptive trait variations displayed significant correlations between allele frequency variation and climatic factors for the population origins of the tested material (Table 2 , see Figure 3 ), of which four were highly significant ( P < 0.005).

The correlation coefficients of all regression lines relating changes in HR to changes in MAP were highly significant (P<0.005) and ranged from 0.89 to 0.99.

First, the signature in V5- lac Z-expressing cells had to have a highly significant ( p <0.005) positive or negative response to LeTx treatment while in cells expressing V5-MEK1cr or V5-MEK2cr showed a highly significant ( p <0.005) response to LeTx treatment in the opposite direction.

At these thresholds, the Kaplan-Meier analyses based on PFS ( Figure 4a ) and OS ( Figure 4b ) both show highly significant differences between patients scoring below the threshold and those scoring at or above it: PFS analysis p <0.005, OS analysis p = 0.002.

When comparing genders, the total stress scores were highly significant ( P <0.005).

Furthermore, 42 metabolites showed a highly significant association with the maximal total Sequential Organ Failure Assessment (SOFA )score during the course of the disease (i.e., Pearson’s correlation test, p -value < 0.005, and correlation factor > 0.6); these top-ranked metabolites included 23 amino acid metabolites and a subset of pregnenolone/progestin metabolites.

Of these, 5 candidate genes, including BGLAP , SLC2A9 , EGFR , CD44 , and HAO1 , had at least one SNP that showed highly significant differences of allele frequencies between the patient and control groups at P < 0.005.

The correspondence × cue validity interaction was highly significant, F (1,19) = 15.0, P < 0.005, showing a strong modulation of attentional cuing on the Simon effect.

All correlations yielded highly significant results at p <0.005.

The significance of differences was considered significant when P <0.05 and highly significant when P <0.005.

There was no statistically significant difference in disease duration since the introduction of the first csDMARD or bDMARD treatment, but the duration of disease at the introduction of the current bDMARD treatment was significantly shorter in the reduced-dose group than in the stable-dose group (9.7 vs 12.1 years, p = 0.034) (Table 1 ). In addition, we noted that there were proportionately more patients treated concurrently with MTX in the reduced-dose group than in the stable-dose group, and the difference was highly significant (86.7% vs 73.8%, p = 0.005).

The nonparametric mITT-LOCF analysis demonstrated a highly significant, medium to large superiority of Cerebrolysin relative to placebo from day 7 onwards, peaking at day 30, with an MW equal to 0.66 (95% CI: 0.55-0.78; P=0.005; Fig. 2 ).

Analysis of the pooled data showed a statistically highly significant change away from the level of gene silencing of the food they had been living on (P<0.005) and toward the level of gene silencing they were moved to.

When compared to skin spacers, the proportion of shared spacers in saliva over time in each subject was highly significant (p < 0.005 in all subjects for SGII and SGI spacers) (Additional file 1 : Table S4).

Higher prevalence of anemia was observed among overweight participants with 10 out of 26 (38.5%) subjects compared to obese with two out of eight (25.0%) and normal weight 21 out of 172 (12.2%); this difference was highly significant ( P = 0.005).

All effects were significant ( P < 0.05 ) and highly significant ( P < 0.005 ) at 100 and 300 mg/kg respectively.

The difference is highly significant between the emm pattern A-C and E strain groups ( p < 0.005), but not significant when pattern D and E strains are compared.