“highly significant”

All the comparisons were determined to be highly significant (p<0.005) respectively (Figure 1 ).

The results of the goodness-of-fit analysis of the OPLS-DA model showed ( Figure 2D ) that after 200 random simulations, the goodness-of-fit R 2 Y value was 0.999 and the predictability Q 2 value was 0.991, which were at highly significant levels ( p < 0.005).

The RA patients with an insufficient response to MTX who received the tacrolimus-MTX combination showed highly significant improvement in the DAS28 after 4 weeks (n = 10, baseline: 4.51 ± 0.31 to 4.03 ± 0.28, P < 0.005), 12 weeks (n = 9, baseline: 4.59 ± 0.34 to 3.38 ± 0.29, P < 0.01) and 24 weeks (n = 8, baseline: 4.45 ± 0.35 to 3.12 ± 0.34, P < 0.01) ( Figure 1 ).

In contrast, injection of 1000 μg resulted in a highly significant difference (P < 0.005, Mann-Whitney U test) between uptake in tumors with high and low HER2 expression.

A p -value > 0.05 indicated that the data followed a normal distribution and justified the use of t -tests: Differences were considered as “highly significant” in cases with p -values ≤ 0.005, as “significant” with p -values ≤ 0.05, and as “borderline significant” with p -values between 0.05 and 0.10.

Among the 32 subjects in the bryostatin treatment group in the Moderate Stratum Cohort in the #203 study, we found a difference = 4.1 points (with imputed data) in the mean SIB at week 13 from baseline (See Table 5 below), a result that is highly significant ( p = 0.005).

The statistical analysis was carried out using one-way analysis of variance (ANOVA) with significance set as p < 0.01 and a highly significant value of p < 0.005.

The removal of one influential data point (see figure 1 ) weakened these relationships, becoming non-significant for ROUTINE ( p = 0.27), marginally significant for OXPHOS ( p = 0.057) but remaining highly significant for ETS ( p = 0.005).

Clinicopathological correlations in the current study were highly significant ( P <0.005).

defensa was highly significant ( p < 0.005), producing 5.56 ± 0.62 nymphs per female, as compared to wheat aphids without H. defensa , producing only 1.75 ± 0.44 nymphs.

Under brackish conditions, Na + showed a highly significant (p<0.005) gradual increase in the pore water over time.

Highly significant positive correlations between ASL-ATT and CTP-MTT were obtained by voxel-level-wise associations in the gray matter, white matter, and whole brain (all P < 0.005), and the average Pearson correlation coefficients were 0.787, 0.707, and 0.799, respectively.

The final tissue shows a highly significant reduction ( p < 0.005) in MMPI release compared to the complexes modified with active molecules.

The maternal profession was highly significant ( p = 0.005) with the under‐five ARI development.

For SNP rs17315309 A/G, the distribution of heterozygous genotypes showed highly significant differences between the patient and healthy groups ( P = 0.005), with the mutant G-allele being significantly more prevalent in patients than in the healthy group ( P = 0.001).

Meanwhile, the correlation analyses indicated that PLT and AFP levels had highly significant negative (r = −0.1669, P =0.005) and positive (r = 0.5191, P <0.001) correlations with the LS value, respectively ( Figure 3 A,B).

Only highly significant gene-sets (p < 0.005; FDR < 1%) are shown as nodes in the enrichment map.

After seven days of intracerebroventricular (ICV) infusion of BDNF (1.2 μg over 24 h), WT mice experience a highly significant ( P = 0.005) decrease in food consumption and a significant ( P = 0.01) decrease in body weight, whereas mice receiving infusion of artificial cerebrospinal fluid do not.

Statistical significance was determined by a two-tailed p -value < 0.05, with hierarchical notation based on the degree of difference: * p < 0.05 (statistically significant), ** p < 0.01 (highly significant), *** p < 0.005 (extremely highly significant), **** p < 0.0001 (profoundly significant), and ns (no significant difference between groups). 3.

P -values for non-progression as measured by ES were highly significant ( p < 0.005), indicating a slowing down in joint erosion during ETN treatment.

However, among SOX11 positive cases we found a highly significant correlation between SOX4 and SOX11 (Spearman's correlation coefficient: 0,56; p < 0,005), SOX12 and SOX11 (Spearman's correlation coefficient: 0,63; p < 0,005) and moderate correlation between SOX12 and SOX4 mRNA (Spearman's correlation coefficient: 0,40; p < 0,005).

The shape differences between embryos of these two genotypes at this stage, although relatively small, were highly significant ( P <0.005; Procrustes permutation test; data not shown).

When both age and diabetes were taken into account by taking all three groups of testing subjects into consideration ( Table 5 ), MEI SS (RRI), MEI LS (RRI), and MCEI LS (RRI,CT) were found to be negatively associated with age in a highly significant way (all p < 0.005).

A highly significant increase in both the proportion and the absolute numbers of gamma/delta T cells (p < 0.005 and < 0.001, respectively, Student's t test) was observed in nonimmune P. vivax patients during clinical paroxysms compared to nonmalarial controls.

Whatever the outcome considered, adjusted results showed a highly significant difference ( P ≤0.005) in the incidence of inhibitors among the groups receiving the three most used products between 2001 and 2016.