Notably, high CRP levels emerged as a highly significant independent risk factor for poor efficacy of high-dose CRRT (OR = 3.276, p = 0.007) in our study.
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This association remained highly significant after adjustment for clinical factors (p=0.007; B=0.906; 95% Cl: 0.248–1.565).
15.4% in the control group, and the difference was highly significant (P = 0.007) [ 16 ].
The T allele caused a highly significant increase in the risk of CCA compared with the C allele (OR = 2.324, 95% CI: 1.250-4.324, p = 0.007).
DJ-1 expression was linked to nodal status (P = 0.009), a highly significant association of DJ-1 expression with shortened patient overall survival (5-year survival rate 88.0% versus 53.9%; P = 0.007; log rank test) was demonstrated.
Such effect of the I-allele in lowering the susceptibility of normal WHR subjects to hypertension was highly significant at p = 0.007 with odds ratio (OR) = 17.29 and confidence interval (CI) = 1.813–164.96.
Late 2010/early 2011 inventories and MAR were compared to late 2011 and 2012 inventories and MAR with a student’s T test and differences between the two time periods were highly significant, p = 0.007 for MAR and p = 0.0018 for inventories ( Table 3 ).
In contrast, a highly significant decrease in volumes was observed in cohort B (before vs. after AcPSMA RLT): the mean Volume-SG was 50 ± 13 mL vs. 40 ± 11 mL ( p = 0.007, Figure 1 B).
Kaplan-Meier survival estimates revealed a highly significant difference in the proportion of patients surviving the follow-up period (log rank 7.25, p=0.007) with FTD patients experiencing poorer survival than those with AD.
In addition, it became highly significant in the recessive model for the PD and LOPD group (OR: 1.331, 95% CI: 1.082–1.637, p = 0.007) ( Table 4 ).
intermittent use), and positive and negative symptoms indicated that the group (i.e., FEP)-specific link between HDL and verbal learning remained highly significant ( F = 7.45, p = 0.007).
This model explained 63% of variance and was highly significant ( R 2 = 0.63; F (2,10) = 8.38, P = 0.007; see Table 2 and Fig. 4 ).
Statistical analysis confirmed that the reduction achieved by melanin was highly significant compared with the control (p = 0.007, Student’s t-test).
In contrast, numbers of activated non-regulatory T cells were reciprocally impacted: more CD4 + CD25 + FoxP3 − CD127 + cells were induced by stimulation with TLR-3-DCs (0.8%), with a highly significant difference to cc-7-DCs (0.2%; p = 0.007).
This increase was modest in magnitude (Cohen's d = 0.35) but statistically highly significant ( P = 0.007).
However after surgery, RM-ANOVA revealed a highly significant main effect of treatment group on path length during reversal trials (F 1,21 = 8.7, p = 0.007), which demonstrated that MWM reversal was markedly impaired in mice with mPFC lesions.
The subsequent analysis revealed a highly significant Sex × ADOS‐2 interaction for aggressive actions (IRR = 1.42, p = 0.007; Figure 3a , Table 2 ).
We therefore excluded it which rendered the correlation highly significant ( r = −0.5826 P = 0.007, Fig. 4 ).
The ANOVA of theta responses revealed highly significant differences for Qigong technique, F (1, 19) = 9.20, p = 0.007, η p 2 = 0.33.
For SSOSL85, the H10 model had a lower AIC value than the neutral model (H00), and the difference was highly significant (H10 vs H00, P = 0.007).
This trend was consistent with the training set, where a highly significant difference was also observed ( p = 0.007).
Highly significant results were found for the PMP group ( p = 0.007) and the total population ( p = 0.001), while for the MP group, although an improvement trend was observed, no significant results were recorded.
To assess the robustness of our findings, a sensitivity analysis using a clinically significant SNHL threshold (Chang ≥ 2a) was performed: both cochlear dose and cisplatin exposure remained associated with increased risk, though the former did not reach statistical significance (p = 0.07) due to reduced power while cisplatin exposure remained highly significant (HR = 6.21; p = 0.007).
This association was highly significant (p=0.007) based on our permutation test.
There was a highly significant relationship between strong leptin expression and lack of histopathological response to neoadjuvant chemotherapy ( P =0.007, Figure 2B ), consistent with the results from gene expression profiling in the discovery set.