The GCLC SNP (Single Nucleotide Polymorphism) rs1555903 also showed a highly significant ( p = 0.007) main effect on mercury retention in the umbilical cord in a UK birth cohort (Julvez et al., 2013 ).
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In contrast, a highly significant decrease in volumes was observed in cohort B (before vs. after AcPSMA RLT): the mean Volume-SG was 50 ± 13 mL vs. 40 ± 11 mL ( p = 0.007, Figure 1 B).
The exposure to 300 Gy X irradiation induced a highly significant ( p ≤ 0.007) increase in meiocytes displaying oxidized DHE relative to control ( Figure 3 A), thus revealing IR-induced generation of superoxide and other ROS radicals in all strains tested.
When we combined the heterozygote AG and homozygote AA as a pooled risk genotypes comparison group, assuming a dominant effect of the variant A allele, the combined genotype XA (AG+AA) was associated with a highly significant 56.4% increased risk of higher Gensini score ( p = 0.007, OR = 1.564, 95% CI = 1.132∼2.162) relative to the GG genotype.
As indicated in Figure 3 , the mean statistical values for the contrast threat minus neutral anticipation in GAD patients as compared to HC extracted from the overlapping cluster of all significant Sustained Response GLMs, followed a highly significant quadratic function with the delay of the sustained response predictor (function: y = −0.022 x 2 + 0.297 x + 2.291, R 2 = 0.96, P < 0.007).
The effect was highly significant when the groups were combined (P = 0.007).
The reduced proliferation signature could stratify stage I patients in two groups with highly significant differences in prognosis ( Figure 3B : HR=5.92; 95% CI: 1.62–21.59; P =7.03 × 10 −3 Wald test).
56 + 0.60 ∗ ANB + 0.10 ∗ 21 / ANS-PNS , with ANB ( P = 0.000060) and 21/ANS-PNS ( P = 0.003187) being highly significant, as was the intercept ( P = 0.007069).
Though there was an interaction between sex and ẟ 15 N on the skin, the effect of sex alone was highly significant ( p = 0.0071, df = 1) for the bacteria Staphylococcus sciuri (Firmicutes); males showed a 15% decrease in abundance of this species.
The hNIS expression in pre-menopausal women is found to be highly significant when compared with the post-menopausal group (p = 0.0071). hNIS and HER2 Receptor Expression Overlaps at the Tumor Cell Membrane in Few cases As hNIS is a transporter protein, except for a few reports [5] , [6] that have shown distinct membrane staining, mostly it appears as an intracellular protein in breast tumor tissue sections.
The reduction in salivary NO 2 − in the other 12 participants (i.e., from 22 ± 11% to 17 ± 11%) was still highly significant (t = 3.245, DF = 23, multiplicity adjusted P = 0.0071).
In the interpretation of our results, it is important to note that while the P ‐value for the odds ratio for female sex reporting difficulty is highly significant ( P = .0071), the lower bound of the 95% confidence interval (1.098) is very close to the point of no effect (1.0).
By using Two-way ANOVA, we showed that age (17 and 17.5 d) and treatment interaction was highly significant (p = 0.0071), indicating that the effect of PD98059 depended on the period of the day.
However, in recessive mode, The TT genotype showed a significantly lower frequency in patients (15%) compared to controls (1.66%), supporting its role as a protective factor with a highly significant p -value (OR = 0.09 and p =0.0071).
The RMSD value of 0.237 was highly significant (permutation test p-value ≤ 0.0072), confirming that identical genomic sequences folded into very similar local structures despite the very different context.
In the acute schistosomiasis group, highly significant positive correlations were found between eosinophil count and infection intensity (Pearson correlation = 0.477; P = 0.0072), and eosinophil count and the level of sICAM-1 (Pearson correlation = 0.363; P = 0.0014). 3.3 Immunoglobulin levels in the different clinically defined disease groups ANOVA post hoc tests showed all SEA- and SWAP-specific total IgG and SEA-specific IgG4 levels were significantly higher in the acute, chronic and advanced groups compared with controls ( Fig. 2 ).
population improved the model fit, and the relationship was highly significant (adjusted R 2 = 0.3933, p = 0.0073).
To distinguish between the effect of calciuria on basal AQP2 from DDAVP-stimulated response, the Bonferroni/Dunn post hoc test was used and showed a highly significant effect of urine calcium concentration on basal AQP2 levels (p = 0.0073), but no significant effect on AQP2 levels following DDAVP stimulation ( Fig. 1B ).
By contrast, the difference in mean plaque score between the most deprived group and the least deprived group was highly significant in men in the two highest age tertiles (46.8-56.2 years and 56.3-66.5 years; P=0.0073 and P<0.001) and in women in the highest age tertile (56.3-66.5 years; P<0.001).
Applying this cutoff value, there was a highly significant difference in the cancer detection rate using MRI-guided prostate biopsy between males with a PSA ratio <0.15 compared to those with a PSA ratio ≥0.15 ( P = 0.0073, Fisher's exact test).
A linear model assessing log pfu/ml recovered from nasal lavage of directly inoculated cats as a function of both inoculation dose and dpi of sample collection was highly significant ( P = 0.0073, R 2 = 0.41).
A highly significant positive correlation was observed between temperature and the T. urticae population on strawberry plants (r = 0.921, p = 0.0074).
In contrast, 25% of the etomoxir-treated rats had normal behavioral scores, which were highly significant compared to the placebo group (p = 0.0074; chi-square) ( Fig 3c ).
The strongest effect was observed when the study by Tane (2024) [ 9 ] was omitted (OR: 0.6190, p = 0.0137), while the weakest effect remained highly significant when the study by Aguinagalde (2024) [ 10 ] was excluded (OR: 0.6764, p = 0.0074).
SFOx consumption caused a highly significant (p = 0.0074) negative consequence on body weight gain and final body weight, in comparison with the other two groups.