“highly significant”

In the brain-specific gene set, a highly significant positive correlation ( r = 0.992; P = 0.0079) was observed; that is, genes that are located in close proximity to more human-specific TF-binding sites manifest higher rates of protein evolution ( fig. 4 and supplementary fig.

8 Further analysis revealed that memory T cells (CD45RO + ) were predominantly affected within the CD4 + and the CD8 + T cell population, resulting in a highly significant reduction in CD8 + as well as CD4 + memory T cells ( figure 1B ; 29.90%, p = 0.0079 and 31.13%, p = 0.0002, respectively).

By applying each risk score to the additional validation series of controls and JMML samples ( Online Supplementary Table S5 ) we confirmed highly significant differences in the discriminatory potential with both models ( P =0.0079 and P =0.0008; Figure 3C ).

3E ); this difference in outcomes was highly significant (p=0.0079; Fisher exact test).

The highly significant reduction in uACR in APP/PS1 mice compared to wild-type ( p = 0.0079) is consistent with glomerular microvascular dysfunction.

But after one week of neuronal differentiation, we could show a highly significant (p = 0,0079) increase of nuclear NF-κB RELA in females only.

There was also a highly significant negative association of immunologic response among individuals who had baseline CD4+ cell counts between 350 and 500 (AHR = 0.285; 95% CI: 0.1128–0.719; p<0.0079).

We now show that there is a highly significant main effect of virus (n=5 P35 and 3 P115 mCherry cells and 7 P35 and 6 P115 hM4DG i -mCherry cells, 2way ANOVA, F (1,17) =9.069, p=0.0079) but no main effect of age (n=5 P35 and 3 P115 mCherry cells and 7 P35 and 6 P115 hM4D cells, 2-way ANOVA, F (1,17) =0.1391, p=0.7138) nor any interaction of age and virus (n=5 P35 and 3 P115 mCherry cells and 7 P35 and 6 P115 hM4D cells, 2-way ANOVA, F (1,17) =0.9260, p=0.3494).

Highly significant correlations in gene expression were observed between qRT-PCR and RNA-seq ( R 2 = 0.5217 to 0.9479; p = 7.98E-3 to 9.66E-8; n = 12), indicating the RNA-seq data were reliable.

In the six grouping that excluded o2 from enrichment, a central component of ER translocation, the Sec61-β protein, was a highly significant ( P =0.008) protein.

A pairwise comparison of PFS between patients with PD-L1 + and PD-L1 − tumors also showed a highly significant difference in PFS outcome ( P = 0.008).

Furthermore, BPs with SAs demonstrated a highly significant ( p = .008) poorer compliance.

From the Kruskal-Wallis and Dunn post hoc tests, we have found that the difference between the d-spacing of the EMT positive lesion and non-lesional tissue is highly significant (p < 0.008).

The difference between the unaided and the aided condition was highly significant and clinically relevant in both groups ( p < 0.008).

Accordingly, when SS and PS perfusion levels were expressed as a fraction of resting state perfusion level (SS/RS and PS/RS, respectively), ANOVA detected a highly significant genotype effect on both SS/RS ( F (2,26) = 5.848, p = 0.008) and PS/RS ( F (2,26) = 7.201, p = 0.003).

TMJ disorders were highly significantly more frequent in males versus females ( p = 0.008 **), a highly significant difference that reflects sex-specific biomechanical or parafunctional habits contributing to temporomandibular joint dysfunction.

Interestingly, in lymph node positive patients, there was highly significant correlation between FGF19 expression and age of patients (p=0.008).

This corresponds to a highly significant dose reduction of 59 % ( p = 0.008) for the maximum heart dose and 75 % ( p = 0.008) for the D 2% of the LAD.

A highly significant increase of the CD34 + CD45 dim CD133 + c-Kit + ( p = 0.008) was observed (Fig. 5f ) while no difference existed in the CD34 + CD45 dim CD133 + c-Kit − population (Fig. 5e ).

When comparing the effects of ZM241385 with MRS1754 regarding their ability to reverse the adenosine-suppressed K Ca 3.1 current, there was a highly significant difference ( p =0.008).

This difference was highly significant ( p = 0.008).

When partitioned into low (n = 16) and high (n = 17) reactive groups, the high reactive group showed a highly significant decrease in SBR during the IT period compared to baseline (11.1 ± 1.09 blinks per min to 6.2 ± 0.95 blinks per min, t 1,30 = − 2.9, p = 0.008) and a significant increase in SBR from baseline during the CT period (11.1 ± 1.09 blinks per min to 15.6 ± 1.71 blinks per min, t 1,30 = 2.7, p = 0.012).

An analysis of covariance (ANCOVA) showed that freezing during the last three trials of extinction does not predict freezing at 24-h recall, F (1,37) = 0.96, P = .34, and the effect of phenotype on 24-h recall remains highly significant even after adjusting for freezing differences during extinction, F (1,37) = 7.81, P = .008.

The 2-marker prognostic signature, based on ATF6α high and p-p38 low levels, showed highly significant association with time to recurrence ( P = 0.008) and a high trend with overall survival ( P = 0.062).

Furthermore, patients with low anti-Gmd titer demonstrated a highly significant 2.7-fold increased risk in adverse outcomes (p=0.008).