Analysis of the microarray data revealed that there was indeed a single, highly significant ( p < 10 −5 ) chromosomal cluster of genes negatively regulated by VHL-1 in a HIF-1–independent manner and that in total this cluster extended over 110 kb to include F56A4.9, Y45G12C.9, Y45G12C.12, and Y45G12C.2 in addition to the six genes validated by RNase protection assay.
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27/96 for vfl2 ) was highly significant ( P < 0.00001 based on Fisher's Exact Test).
Results Copper levels were higher in group II showing statistically highly significant results compared with that of group I with p ≤ 0.00001.
graminis cultures were positively correlated with one another and very highly significant ( P = 0.00001) ( Table 2 ).
Results Tone-matching performance As expected, SZ patients showed a highly significant, large effect-size deficit in the tone-matching task (TMT: z = −8.67 , P < 0.00001, d = 0.98) vs.
However, when considering the combination of adding CBCL+BPRS, this yielded a strong increase in prediction accuracy that was highly significant compared to considering only the SIPS (MSE of SIPS=0.74±0.62, MSE of SIPS+BPRS+CBCL=0.716±0.59, p<0.00001) or separately adding BPRS (p<0.00001), or CBCL (p<0.00001) (see Figure 3C ).
The interaction effects on breast cancer risk of these five TF pairs were all highly significant ( P < 1 × 10 −5 ; Supplementary Data 2 ).
The log 10 Bayes factors recovered under each substitution model exhibit very highly significant linear relationships ( r 2 > 0.99, p < 0.00001 in all cases) and are hence independent of the amino acid substitution model employed (electronic supplementary material, S7).
The difference between the MS and the control group regarding the frequency of a positive MRZ, MRZB or MRZBU reaction, as defined by a bi- or trispecific response, was highly significant ( p < 0.00001, Mann–Whitney U test, irrespective of whether the single steroid-treated control patient was included or not).
The differences of observed GFP + cells between C-GFP subclones and A-GFP subclones were highly significant (P < 0.00001).
Studying the individual genes in the 12-gene and 72-gene signatures, revealed that the great majority were overexpressed in the EpCAM + /ITGA6 + /ALDH + population compared to all other luminal/LP populations, a result which was highly significant as assessed using 100,000 Monte-Carlo randomizations (Fig. 6b , P < 1e−5).
Preoperatively this range averaged 2.8 mmHg (SD 2.4, MAX 14, MIN 0) which was decreased to 1.8 mmHg (SD 1.7, MAX 10, MIN 0) at month 12, a difference that was highly significant (P<0.00001).
All components of variance were highly significant (P<1×10 −5 ).
This study showed that duration of analgesia was 37% higher for Bupivacaine which lasted for up to an average period of 7.3 hrs which was highly significant (p=0.00001*).
The results were highly significant for all parameters (Wald χ 2 (1) < 10,000, p < 0.00001 in all cases).
This was in stark contrast to all our previous results where Levene’s test most often gave highly significant results ( P < 10 −5 ) and a quite tight posterior distribution.
There was a statistically highly significant reduction in the number of days taken for alignment of anterior teeth with the application of LASER ( P <.00001).
This difference was highly significant (p < 0.00001).
The increase in PNN density (normalised to the cross-sectional area of the neostriatum) between P10 and P14 was highly significant (one-way ANOVA, Tukey-Kramer test; F(5, 48) = 142.14, P<<0.00001; Fig 7A ).
As demonstrated by the high odds ratio (log 2 (OR)>6) between all the data sets, we showed that there was a highly significant overlap in RI (Fisher’s exact adjusted p<1e−05, Figure 1—figure supplement 2a ).
ESM-1b t s + ECFP) is statistically highly significant (McNemar’s test: p < 10 −5 ).
The tests are all highly significant, with p < 0.00001.
Differences between collaborative cross strains in total luciferase expression were highly significant (F 11,44 = 9.64; p < 1 × 10 −5 ).
Because of the large number of samples, the comparisons gave highly significant results, typically with p < 0.00001 after Bonferroni correction. 2.6.4 Simple and complex extensions of spectral statistical parametric mapping (sSPM) In our more recent studies' we have standardized the frequency domain analysis.
The addition of DEX significantly decreased the onset time of anesthesia of nerve blockade by an average of −48.78 s in comparison to the control (95% CI: −64.22 to −33.35; I = 95%), favoring DEX, with a highly significant overall effect (Z = 6.20, p < 0.00001) (Fig. 3 a).