“highly significant”

Statistical analysis showed highly significant differences (**** p < 0.0001) in cell viability across treated groups of both H1299 and HEK-293 cells.

The sulcal depth of the aaLF and ds Comparison of the aaLF and ds depths showed a highly significant difference (p < 0.0001).

The analysis contrasting groups within each subphase showed that the AO: PMDD+ group had a highly significant increase in food cravings relative to all three study groups in the LL subphase: the AL: PMDD− group ( t -ratio = 5.27; p ≤ 0.0001), the AL: PMDD+ group ( t -ratio = 4.78; p ≤ 0.0001), and the AO: PMDD− group ( t -ratio = 4.87; p ≤ 0.0001) ( Table 2 ).

Robustness Analysis FDR-adjusted analyses confirmed the stability of the main findings: several group-level effects remained highly significant after correction—most prominently the AI of lobules V, VI, VIIIB, and IX (e.g., Lobule IX Volume Asymmetry: F(1,95)=17.53, P < .0001, q = 0.0012, partial η 2 = 0.156) and the left-sided thickness and volume of Lobule IX (F(1,95) = 10.28, P = .0018, q = 0.0198, partial η 2 = 0.098).

Expression profiling revealed that SLC7A5 was significantly differentially expressed across cell types, particularly between epithelial cells and fibroblasts, mast cells, plasma cells, and T cells, with highly significant differences (p < 0.0001), suggesting cell type–specific functional roles ( Figure 6G ). 3.7 Mechanistic insights into the role of SLC7A5 in BRCA Gene set enrichment analysis (GSEA) revealed that low-SLC7A5–expressing samples exhibited downregulation of pathways related to immune responses, cell adhesion, and proliferation, including allograft rejection, cell adhesion molecules, cell cycle, and cytokine–cytokine receptor interaction ( Figures 7A, C ).

Log-transformed differences between HIV− and HIV+ levels were evaluated by t -test and were highly significant: ADAR ( P =0001), APOBEC3G ( P =0078), MX1 ( P <0.0001), IRF7 ( P <0.0001), MYD88 ( P =0002), RANTES ( P <0.0001) and STAT 1 ( P =0001).

longa extract when added to fluconazole, with a statistically highly significant difference (mean zone diameter = 31.94 ± 6.99, P-value < 0.0001).

Crucially, the interaction between genotype and group status was highly significant (F 2,509 = 22.14, p < 0.0001, η 2 = 0.080), with a statistical power of 99%.

The differences between species richness in NW and RB were highly significant ( P < 0.0001).

The CT heterozygote once more demonstrated a significantly lower risk (OR = 0.36; 95% CI = 0.2–0.5; p = 0.0001) among individuals without a family history, while the TT homozygous mutant genotype demonstrated a highly significant increased risk (OR = 2.79; 95% CI = 1.7–4.3; p = 0.0001).

The difference between values for the TEVGs and PTFE grafts was highly significant ( p < 0.0001).

9.6b ) is highly significant (Pearson r = 0.4982, p < 0.0001, Spearman r = 0.4688, p = 0.0002).

All three responses demonstrate predictive capability with R 2 values ranging from 0.8418 to 0.9576 with a highly significant p -value ( p < 0.0001).

After excluding rhinoviruses and coronaviruses, the difference remained highly significant (31% versus 8%, P < 0.0001).

Furthermore, the 1745 cm −1 band (C Created by potrace 1.16, written by Peter Selinger 2001-2019 ]]> O stretching of esters/lipids) exhibited highly significant differences ( p < 0.0001) between treated and untreated bacteria, particularly for 1a and 1b, suggesting perturbations in the lipid components of the cell envelope or extracellular matrix.

This difference between cDNA and gDNA is highly significant for each replicate: (Family 1: ANOVA, F 1,6 = 443.36, p<0.0001; Family 2: F 1,6 = 39.60, p = 0.0007; Family 3: F 1,6 = 219.02, p<0.0001).

4 D ) and the correlation after pooling across neurons was highly significant (Spearman correlation: ITD: r s = −0.92; ILD: r s = −0.89; both p < 0.0001; two-tailed t test; Fig. 4 E , F ).

The global test revealed highly significant overall differences between groups (pseudo‐F = 43.9, p = 0.0001, 9999 permutations), demonstrating that changes in Δ Lk are associated with systematic shifts in DNA minicircle conformations.

Considering all five species, the difference between the years is highly significant for O. kevoensis (χ 2 = 69.5, P < 0.0001), whereas in O. inclinans the difference is only marginally so (χ 2 = 4.6, P = 0.03).

ANOVA results revealed that dielectric type was the most dominant factor, contributing 33.0% to MRR variation with a highly significant F-value of 24.63 ( p < 0.0001).

Increases in effect sizes of those SNP alleles were highly significant (P < 0.0001) for milk yield between all 10-day intervals as well as for fat content (P < 0.05), except for the first two 10-day intervals.

Overall, differences in species richness between elevational zones <2000 m were highly significant (ANOVA, F = 244.04, P <0.0001).

mTORC1 also exhibited a stage-dependent upregulation in Stage II, III, and IV, respectively, with all differences being highly significant ( p < 0.0001).

The enrichment of the identified proteins with oxidoreductase activity or involvement in cell redox homeostasis as determined using the ProfCom database was statistically highly significant (p<0.0001).

The difference among the groups was highly significant ( χ 2 : 24.98; P <0.0001) ( Figure 1 ).