“highly significant”

In our study, we found a statistically highly significant correlation between the degree of fibrosis and the NFS score ( p <0.0001, chi -square and Fisher’s exact tests) (Table 6 ).

Importantly, multivariable Cox analysis demonstrated that CCNF remained a highly significant predictor of OS independently of histologic grade and TNM stage (HR 2.86, 95% CI 2.02–4.06, p < 0.0001; Table 4 ).

A highly significant treatment effect was detected for the discrimination index (F(2, 21) = 157.2, p < 0.0001, R 2 = 0.9374).

Genotyping of these markers in the FG/FZ strain revealed a highly significant difference in the distribution of genotypes between the dead and alive mosquitoes for all the nets (χ 2 > 20; p < 0.0001) ( Figure S4 ).

The PERMANOVA showed a highly significant difference between the three populations ( F = 8.79, DF = 2, P = 0.0001) as well as for each pair of populations ( S2 Table ).

Nevertheless, the pairwise Pearson correlation of the GLS Area Under Disease Progress Curve (AUDPC) in all four environments was highly significant ( P < 0.0001) with correlation coefficients ranging between of 0.45-0.72 (Table 1 ) indicating that artificial inoculation was efficient to develop a biologically meaningful phenotype.

However, a highly significant difference was found when comparing the TB 1-9 group to the severe COVID-19 group ( p < 0.0001), underscoring a pronounced deviation in magnesium levels corresponding to disease severity, as depicted in the heatmap, with varying shades of blue indicating the strength of the correlations ( Figure 3 ). 2.3.

For the risk level model (Table 3 ), the Spearman rank correlation coefficient between the originally measured PROCAM scores and the corresponding predicted risk level values was 0.74, which was highly significant (p < 0.0001).

A paired t-test was applied and with considering a significance threshold of 0.05, the difference in forecasting accuracy between the models showed to be highly significant with p ≤ 0.0001 across subjects.

For garden warblers, the positive effect of day on SMI was substantial and highly significant (0.93±0.08, P <0.0001, Table 1 ).

The amount of MON deposition under infinite-dose conditions was examined from three formulations: MON-NLC, MON-NLC gel, and MON in water across the epidermis, dermis, and the receiver chamber of the Franz diffusion cell after 24 h application ( Figure 11 ). A significant finding was that the MON-loaded NLC gel left much less MON on the skin surface (59.50 ± 505.81 ng/cm2) as extracted from the skin wash compared to the MON-loaded NLC (14313.11 ± 118.88 ng/cm2), with a highly significant p-value of <0.0001.

melliferum populations were more stable year to year ( P = 0.0544) but showed highly significant seasonal variation ( P < 0.0001).

Figure 3 shows the OR (95% CI) , where the history of GDM was found to be a highly significant risk factor with OR 3.91 (95% CI) (1.93 to 7.95) (p<0.0001).

galegae , the LRT was highly significant (P < 0.0001), and the parameter estimates for N. galegae nifQ indicated an increase in the relative rate of non-synonymous substitution by a factor of 3.

The regression models were highly significant ( p < 0.0001) and accurate (lack-of-fit, p > 0.05) for all response variables ( Table S2 ), indicating good model adequacy.

Immunophenotyping revealed marked increases in EVs derived from neutrophils (CD66 + , CD16 + ), T lymphocytes (CD3 + ), leukocytes (CD45 + ), platelets (CD41a + ), and endothelial cells (CD51/CD61 + ), all of which were highly significant ( p < 0.0001).

The difference in the two-sample test was highly significant ( P = 0.0001).

Pearson’s correlation analysis of the whole-blood platelet concentration and all PRP platelet concentrations revealed a highly significant correlation ( p < 0.0001).

The random effects for feed and COM, the zero inflation parameter, and the square root concentration effect were all highly significant (p<0.0001).

Chi Square analysis of these total success rates confirmed a highly significant difference between account holders and personal attackers [ χ 2 (1) = 232.6, p < .0001].

For roots, there were again highly significant differences among the groups of accessions on both axes (PCA1: F 3,100 = 12.58, p < 0.0001; PCA2: F 3,100 = 17.88, p < 0.0001).

Furthermore, the median survival time (TTH) of Surgicel was lower than that of Arista, PerClot, and 4DryField, and the log-rank test showed that the difference in time to achieve hemostasis between Surgicel and each of the test articles was also highly significant ( P < .0001; Supplementary Table S3 ).

The clustering observed was found to be highly significant, and we identified 159 unexpectedly large (at least 400 Kb; p<1e-04) clusters of divergent regions with a median size of 800 Kb ( Figure 3 ; Table S2 ).

The Candiolo nomogram is highly significant for the stratification of both bPFS and cPFS (P < 0.0001), as well as the D’Amico classification (P = 0.004 and P = 0.001, respectively).

Pathologic complete response was a highly significant predictor of DFS and OS in all treatment groups (HR = 0.45, P < 0.0001, and HR = 0.33, P < 0.0001, respectively).