“highly significant”

In DRG cultures of both sexes, 17β-estradiol produced a highly significant (p > 0.0001) 3-fold induction of Il6 ( Fig. 5 A) and Cacna2d1 ( Fig. 5 B) expression.

Correlation of ELISpot Responses to Various BK Virus and JC Virus Peptide Pools Spearman analysis indicated that, in 17 HSCT recipients with BKV-related cystitis and in 50 healthy controls, responses to the BKV LT and VP1 peptide pools showed a highly significant correlation ( r > 0.7, p < 0.0001) ( Appendix B , Table A2 ).

The results of third pair CCA mode of network and gene variate were again highly significant (Fig. 3 C, r = 0.97, p < 0.0001), as was fourth pair CCA mode of network and serum lipid variable (Fig. 3 D, r = 0.82, p < 0.0001).

5C , p < 0.001, n = 14–27/group), specifically resulting from a highly significant reduction in the length of non-apical dendrites (Fig. 5D , p < 0.0001, n = 14–27/group), in line with previous observations related to increased expression of xlr3b and xlr4b [ 61 ].

The results from the ANOVA table revealed that the model was highly significant (P < 0.0001), while the lack of fit of each model was not significant (P > 0.05) revealing that the model adequately described the relationship between the independent variables (extraction time, solid to solvent ratio, % NADES content and amplitudes) and the dependent variables (TPC and DPPH).

Influence of centrifugation and residual platelet count on plasma PAI-1 activity levels, euglobulin clot lysis time (ECLT) and global fibrinolytic capacity (GFC) of plasma Correlation of plasma PAI-1 activity levels with ECLT and GFC was statistically highly significant, with a Pearson coefficient of 0.63 ( p < 0.0001) and 0.64 ( p < 0.0001), respectively.

These results demonstrate a highly significant correlation (χ 2 (3) = 29.1, p ≤ 0.0001) between the presence/absence of toxicity rescue by olaparib and the presence/absence of the DNA ring morphologies in these samples ( Figure 4 D).

In the APR screening, sequential restricted maximum likelihood ratio tests revealed highly significant variation due to genotypes ( P < 0.0001) (Table S 2 ).

Household Food Analysis Households constitute the largest source of food waste, averaging 69.66 kg per capita, with highly significant country-level variation (Chi-square = 80.03; p < 0.0001).

The Kaplan–Meier survival curves ( Figure 4 F) further confirmed a highly significant difference in outcomes between the two groups (Log-rank p < 0.0001), demonstrating the model’s strong prognostic discriminative power.

One-way ANOVA demonstrated a highly significant effect of incubation time on biofilm formation ( p < 0.0001, R 2 = 0.966).

There was a highly significant linear trend across quartiles of PHPT-GRS scores (chi-square for linear trend extended Mantel-Haenszel test = 98.9; P < 1.0e-04) as shown in Fig. 2 .

The ANOVA data indicated that this regression model was highly significant ( p value < 0.0001) with an F value of 84.71.

Together with detection of a highly significant ( P < 0.0001, by unweighted UniFrac) difference in beta-diversity distance in the TWK10-hk group after administration relative to the TWK10 group, these findings indicate that six-week administration of heat-killed TWK10 has a stronger effect in rearranging microbial community structures than viable TWK10 ( Figure 3 B,C).

The result obtained in the Friedman test was highly significant and showed a p value < 0.0001, highlighting relevant differences between the compared matrices.

Highly significant differences in life stages mortality among concentration were found by direct spray (df = 4, 149, p ≤ 0.0001) for 2nd instar: F = 26.01, 3rd instar: F = 22.20, 4th instar: F = 18.04, 5th instar: F = 13.63, and adult: F = 6.25 and by contact (df = 4, 149, p ≤ 0.0001) for 2nd instar: F = 16.06, 3rd instar: F = 9.95, 4th instar: F = 21.23, 5th instar: F = 6.29, and adult: F = 3.78 with an obvious decreasing pathogenicity pattern from younger to older instars to adult stage at all concentrations.

The hazard ratio in the Cox proportional hazards model is 2.619 (95% CI 1.733–3.956) with a highly significant p -value<0.0001, indicated that the ZingiVir-H treated group had a significant recovery period.

The overall effect of the IIRC grouping was highly significant ( p < 0.0001) ( Table 3 ).

However, when comparing G-II with G-III, a highly significant decrease in AST, ALT, ALP, and prothrombin ( p value <0.0001) was observed in G-III (data not shown in this work). 4.

A statistically highly significant interaction of beverage type × storage time was also demonstrated ( p < 0.0001).

CNV Score and Cell Cycle Analysis in Right-Sided Colon Cancer The CNV score analysis ( Figure 3 A,B) revealed that Tumor cells had significantly higher CNV scores compared to B cells and Proliferating cells, with the difference being highly significant ( p < 0.0001, Kruskal–Wallis test and pairwise Wilcoxon test).

3.1.2 Reproductive traits Analysis of variance revealed that the reproductive traits anthesis days, silking days and anthesis silking interval showed highly significant differences (P ≤ 0.0001) in both the seasons, between the genotypes ( Table 3 ).

Of note, the overall survival of IDH-WT patients in our cohort was worse than the one of IDH-m patients and, as expected, the difference was highly significant using the Kaplan–Meier method (p < 0.0001, Log-rank test, Fig.

There were highly significant positive correlations between TEM and CTX (r = 0.98, p -value < 0.0001), pai (r = 0.96, p -value < 0.0001) and hly (r = 0.94, p -value < 0.0001), and also between CTX, and pai (r = 0.96, p -value < 0.0001) and hly (r = 0.95, p -value < 0.0001).

The KMO test resulted in an appropriate value of 0.84, with MSA for the items varying between 0.64 and 0.92; together with a highly significant Bartlett’s test (p<0.0001), indicating that the sample was adequate for factor analysis.