“highly significant”

After logarithmic transformation of both variables, their distributions approached normality ( P > .15 for FVIII; P = .045 for inhibitor titers), and a strong, highly significant negative correlation emerged (r = −.74; P < .0001; Figure 2 ).

At both time-points, the two LPS groups present an anxiety-like behaviour, associated with less locomotor/exploratory activity and highly significant cognitive impairment ( p < .0001).

The gene expression analysis showed highly significant up-regulation in FLT3 of all AML samples [FLT3-wildtype (0.316 ± 0.05 folds) and FLT3-mutants (0.368 ± 0.03 folds)] in contrast of control group (P = 0.0001).

Looking at the association between BCR reactivity of DLBCL cells and the presence of hypophosphorylated Ars2 isoform overall, considering data from both cell lines and cases with cryospecimenderived recombinant Fab, the association was statistically highly significant (Fisher exact t -test: two-tailed P <0.0001).

A Mantel test comparing the three subgroups and surname classifications indicated highly significant (p-value = 0.0001 for 9999 repeats) correlations across the three subpopulation groups with the frequencies of surname origins.

p-Values were taken to be significant: *significant 0.05≥p>0.01; **very significant 0.01≥p>0.001; ***highly significant 0.001≥p>0.0001; ****highly significant p≤0.0001.

When both fully and partially correct responses were considered, the difference became highly significant (χ 2 = 42.22, p < 0.0001).

By contrast, the discovery cohort had a median of four (p10-p90: 1-6) and five (p10-p90: 2-9) mutations at the first and second samplings, respectively, representing a highly significant increase in the number of mutations during disease progression ( P <0.0001).

The model turned out to be highly significant at the permutation test ( p < 10 −4 ), as shown in Figure 9C , and predictive with 100% correct classification rate. 4 Discussion In the present study, the longitudinal multi-omics investigation on a single mother-infant dyad was proposed to examine in depth the relationships among diet composition, gut microbiota metabolism and composition during the transition from breastfeeding to weaning.

Pulmonary function variables showed a highly significant linear correlation between baseline and bracing ( p < 0.0001, except for the FEV1/FVC ratio ( p = 0.0054)).

Furthermore, the regression models used to compute the correction equations for both sexes were highly significant ( F (1, 188) = 1185.8, P < .0001 and F (1, 108) = 593.0, P < .0001 for females and males, respectively) and the CV for the estimate from either model was less than 7.0, indicating that the level of precision was well within acceptable limits.

A highly significant treatment effect ( p = 0.0001) was obtained exclusively for LT, indicating that the mean response profile between the two groups differed only in the second year of repeated measurements ( Table 4 ).

Linear regression models were adjusted for the delivery mode and pregnancy weight gain, which were consistently highly significant ( P < 0.0001 for both covariates).

Statistical study verified that there is a highly significant difference in the prevalence of carbapenemase genes among the tested isolates ( p < 0.0001).

The agreement between the expected and estimated connective field locations shown in Figure 2 a (diagonal cells in the connectivity matrix) is further demonstrated by a highly significant mean (across subjects) Cohen's kappa value (M = 0.68, S.D. = 0.2, t 11 = 12.0, P < 0.0001).

The results indicate that Group (ASD and the two TD groups) and Task (with and without objects) as main factors, are highly significant: (Group: F [2,75] 72,55 p<.0001; Task F [1,75] 220,52 p<.0001).

The model difference was highly significant ( p < 0.0001), the misfit term was not significant ( p > 0.05), and the fit R 2 was close to 1, which proved that the model was well fitted and the regression equation could be used to analyze the effect of the factors on the peroxide value.

The difference in motility scores between the two groups was highly significant ( P = 0.0001).

Results: Our primary outcome was changes in pre-treatment opioid craving scale (OCS) minus baseline, and we found using a mixed model that the active group had a highly significant treatment * time benefit over the sham group, p < 0.0001, effect size at the last follow-up of 1.5.

Construct validity of the DFS-A Scale The exploratory factor analysis of the DFS-A scale showed a KMO measure of 0.92 indicating adequate sampling adequacy and a highly significant Bartlett’s Test of sphericity (χ 2 = 3205.10, df = 190, p value < 0.0001).

Unsurprisingly, strong and highly significant correlations of IL-1R1 mRNA expression and its co-receptor, IL-1RaP , were detectable in all conditions (r ≥ 0.73, p < 0.0001; Table 2 ).

However, the past five-year trend (2015-2019) was different where, the daily average of PM 2.5 and PM 10 levels (2015-2019) were higher by 70 and 155% when compared with the same time period in 2020 (Phase I), which was highly significant (Kruskal-Wallis test, p <0.0001) (Fig.

Then, a two-way ANOVA factorial analysis revealed that the clinical state of the patients’ plasmas tested (“steady state” versus “acute phase”) had a highly significant effect ( p < 0001) on PS-exposure quantification.

Discrimination models were examined using OPLS-DA, revealing highly predictive (Q2 > 0.63) and highly significant ( p < 0.0001) differences between sTBI patients and OI controls using metabolic profiles obtained by DI/LC–MS/MS and 1 H-NMR on day 4 post-injuries (Fig. 1 ).

Thus, there was a highly significant reduction ( p < 0.0001) in CFU compared with the negative control and with the enamel platelets treated with DMSO.