“highly significant”

Using a parametric Poisson model to analyse these data demonstrates a highly significant difference between the two groups ( P =0.0001).

The data indicated highly significant (p<0.0001) difference in serum TGF- β 1 levels between men (mean value: 37.6 ± 0.12 ng/mL, N = 4888) and women (mean value: 35.1 ± 0.12 ng/ml, N = 4254).

There was a highly significant effect of time (F (5, 153) = 12.80, p < 0.0001) and treatment (F (1, 34) = 4.892, p = 0.0338), but no significant interaction (F (5, 153) = 1.584, p = 0.1677) over the 6-week period indicating that the animals learned the rules of the task, with anthocyanin-rich extract fed animals performing better than the control fed animals.

Furthermore, comparing datasets showed highly significant differences (Wilks’ lambda = 0.0119, F(40, 10687) = 592.4963, p < 0.0001), indicating distinct multivariate distributions among the datasets.

While the difference in ORR was not statistically significant ( p = 0.2867), the difference in DCR was highly significant ( p < 0.0001).

Figure 5 a shows the correlation between the CMB count in the whole brain detected by experts and the SHIVA-CMB in the 1992 T2*GRE scans of the MEMENTO participants, demonstrating the highly significant correlation ( Pearson’s R = 0.89, p < 0.0001) and a regression slope close to 1.

The decrease in phagocytosis of each Borrelia strain by the two inhibitors, alone or in combination, were highly significant (p<0.0001).

Of note, there was a highly significant relationship between UH and CNOC status with most departments having the status of both (n=24/72) or neither UH nor CNOC (n=31/72; p<0.0001; Table 1 ).

Since no cell death can be observed in cerebellar slice cultures under control conditions, the cell death after OGD in this region is highly significant ( P < 0.0001) about 380 times higher ( Figure 1F ).

Both of these variables were highly significant predictors of BU (p<0.0001).

Two-way ANOVA showed highly significant time-dependent block for all peptides compared to control ( p < 0.0001, F = 6.83, df = 9).

By contrast, the discovery cohort had a median of four (p10-p90: 1-6) and five (p10-p90: 2-9) mutations at the first and second samplings, respectively, representing a highly significant increase in the number of mutations during disease progression ( P <0.0001).

In particular, a highly significant ORR was seen in patients who developed skin disorders ( P = 0.0001), vitiligo ( P = 0.0004) and thyroid dysfunctions ( P = 0.0127) ( Supplementary Table S4 ).

After stratification by plurality of birth, somewhat weaker but still highly significant associations of ART with ARM were seen among both singletons (OR, 7.7; 95% CI, 4.6–12.7; P < 0.0001) and multiple births (OR, 4.9; 95% CI, 2.4–10.1; P < 0.0001) (Table 5 ).

Looking at the association between BCR reactivity of DLBCL cells and the presence of hypophosphorylated Ars2 isoform overall, considering data from both cell lines and cases with cryospecimenderived recombinant Fab, the association was statistically highly significant (Fisher exact t -test: two-tailed P <0.0001).

Pooled analysis of all trials found a highly significant reduction in recurrence (RR 0·66, 95% CI 0·62 to 0·71; p<0·0001; figure 1 ) and breast cancer mortality (0·67, 0·61 to 0·73; p<0·0001; appendix p 7 ) with chemotherapy plus trastuzumab compared with chemotherapy alone.

On the other hand, podocyte damage groups (MCD, FSGS, MGN and amyloidosis) showed a statistically highly significant upregulation of podocyte CD73 ( p < 0.0001); the significant increase was consistent also when comparing single entities with negative controls ( p at least < 0.001).

Except for one trial (Nep12-1), nematodes per g of roots explained 25–74% of variations in reduction of root biomass, and both intercepts and slops were highly significant ( p < 0.0001) in all trials.

The seed viability ranged from 18% (E09) to 81% (N01), and there were a positive and highly significant relationships between seed germination and viability traits (r = 0.883; P < 0.0001).

The model is highly significant (F-statistic p -value < 0.0001), and the RMSE values suggest reasonable predictive accuracy.

Marbling Score and REA The mean marbling score evaluated in both laboratories for the striploins of different experimental groups showed greater values for the CAB striploins than for the CTNA counterpart ( Table 1 ), with highly significant differences ( p < 0.0001).

There was a highly significant correlation between the coulter counter and blood gas analyzer methods of Hb measurement ( r 2 = 0.98, 95% confidence interval [CI] = 0.97–0.99; P < 0.0001).

Highly significant effect ( p < 0.0001) of treatment and interaction on enzyme activity was recorded (Table 1 ).

The use of ventilators for non-survivors (29.5%) was almost twice that given for the survivors (15.2%), and ICU admission was more than twice for those who died (21.2%) compared to that for the survivors (8.4%), both with a highly significant p -value ( p < 0.0001).

The correlation was highly significant (Spearman’s ρ = 0.74, p < 0.0001) and comparable to that between immunogenicity and MHC complex stability.