“highly significant”

The ANOVA revealed a highly significant main effect (F = 11.54; p < 0.0001), with an R 2 value of 0.4903, indicating that almost 50% of the observed variability is explained by the model.

Hence, when looking specifically at peritumoral tumor cell clusters as a surrogate of glial migration and infiltration, the average results between control condition (8 animals) and all chemokine groups were highly significant: CXCL10 (7 animals): 37 vs. 7 ( p < 0.0001), CCL2 (9 animals): 37 vs. 28 ( p = 0.0258), CCL11 (8 animals): 37 vs. 25 ( p = 0.0003) and the combination (7 animals): 37 vs. 24 ( p = 0.0070) ( Figure 3 D). 2.2.2.

Overall, there was a highly significant difference in RR between the group of MB-stained patients and those without ( p < 0.0001), even if analyzed separately for treatments.

In contrast, oral administration of both DCV and LJV resulted in a highly significant reduction in lifespan compared to the sucrose control ( p < 0.0001 for both), providing the first experimental evidence for the oral virulence of these viruses against SWD .

One-way ANOVA revealed highly significant differences among extraction methods for all phytochemical and antioxidant parameters ( p < 0.0001; Table 2 ), confirming that extraction technology is a critical determinant of bioactive compound recovery from blackthorn berries [ 29 ].

A highly significant association between CEI and mortality was noted (p < 0.0001), with mortality reduction of 8.1 (CI: 6.6–9.6) per 1000 units CEI.

As seen in Figure 2 , this increase was highly significant in the whole-cell ( Figure 2 A p < 0.0001), the cytosol ( Figure 2 B p < 0.0001), and the nuclear volumes ( Figure 2 C p < 0.0001) when compared to the non-treated cardiomyocytes.

In addition, the difference between real synchrony and surrogate synchrony estimated by SUCO was highly significant ( t (44) = 43.80, p < 0.0001).

The differences in GPH and GMH by childhood smoking status were both highly significant (p<0.0001) by the Kruskal-Wallis and Man Whitney U post hoc tests.

Network events resulted in a highly significant positive shift in [Cl − ] i ( P < 0.0001, t -test, n = 75 network events from 16 neurons) and an acidic shift in pH i ( P < 0.0001, t -test, Figures 4A,B ).

Analysis of variance (ANOVA) on IC50 values yielded a highly significant difference among the synthesized derivatives ( p < 0.0001).

The Kaplan–Meier survival analysis showed a highly significant difference in OS was detected between the high- and low-risk groups (Log-rank test P < 0.0001), suggesting that the expression of these 5 genes can be effectively distinguished the high- and low-risk of these PC patients (Fig. 4 B and Fig. 5 ).

The statistical analysis indicates highly significant results (p-value < 0.0001) for the uncontrolled cases.

The model was highly significant ( p < 0.0001) with a non-significant lack-of-fit ( p = 0.0689 > 0.05).

The Kruskal–Wallis test for the lateral region was highly significant ( p < 0.0001).

Statistical analysis using an unpaired t test with Welch’s correction showed a highly significant difference between groups ( p < 0.0001).

Statistical analysis confirmed highly significant effects of HC-030031 antagonism (all p < 0.0001), validating the mechanistic importance of TRPA1 in bacterial sensing.

The differences in MICs, and susceptibility rates between the triple and double combinations were highly significant ( P < 0.0001).

While in the control condition, no significant differences were observed between the percentage of Hi versus Li ROI, the treatments from the 1 h time point to 24 h revealed a highly significant decrease in the Hi-ROIs compared to Li-ROIs (**** p < 0.0001 Hi vs.

The present study recorded a higher prevalence of toxoplasmosis in stray cats (74.6%) than in pet cats (25.4%) with highly significant differences ( x 2 = 20.388; p = 0.0001) as shown in (Fig. 2 ).

Furthermore, the correlation between both methods was highly significant ( p < 0.0001), with Spearman’s r s = 0.9912 for honey, 0.9492 for hive debris, and 0.9682 for both sample types combined. 3.4.

Upregulation of miR-132-3p led to a small, but consistent, enhancement of NMT2 expression (118%) whereas down-regulation of miR-132-3p was associated with a highly significant decrease in NMT2 expression (39%) ( p = 0.0001).

Starting the study with MSCs separated from the adipose tissue of the patients with non-healing wounds for autological transplantation, our attention was drawn by a highly significant negative correlation ( p < 0.0001) between the wound size and wound closure degree and by the high percentage (on average 75%) of CD34 + cells among the isolated cells [ 33 ].

The difference between the wild-type AV-T and AV-T Δ 1132 is highly significant at p < 0.0001 as determined by a Student’s two-tailed t test.

We used automatic image analysis to count LMNA foci and found a highly significant difference between NTRK1-expressing and control cells ( p -value < 0.0001).