All fixed effects showed a highly significant impact on length of productive life ( p < 0.0001).
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A highly significant relationship was observed between the estimation of the first rotation and the overall results of the test ( p < 0.0001); participants who made an accurate estimation of the first rotation had lower average estimation error than those who made an inaccurate first estimation.
Type × vertical position association Cross-tabulation analysis revealed a highly significant association between primary type and vertical position (χ2 = 33.574, df = 4, p < 0.0001).
At both time-points, the two LPS groups present an anxiety-like behaviour, associated with less locomotor/exploratory activity and highly significant cognitive impairment ( p < .0001).
Moreover, a highly significant difference in ATF6 expression was observed between diabetic females and males in this region ( p < 0.0001) (Fig. 4 c).
A highly significant correlation was found among all the indices (p <0.0001 for all) ( Table 2 ).
Finally, logistic regressions show no significant relationships between phenotypic and environmental values at the outset (pseudo- R 2 s ≈ 0.0, P values > 0.1), but show highly significant relationships at the ends of the simulations ( P < 0.0001 for all values of Φ), with the amounts of variation explained increasing as a function of selection strength (pseudo- R 2 = 0.327 for Φ = 0.01, 0.376 for Φ = 0.05, and 0.406 for Φ = 0.1).
Notably, almost all comparisons were highly significant in noncirrhotic patients ( p < 0.0001).
For the total cases, the test statistics of both LM-lag and LM-error were highly significant, whereas Robust LM-error ( p -value < 0.0001) was more significant than that of Robust LM-lag ( p -value = 0.0003).
This was significant only for gata2b u 5008/ u 5008 , but Pearson’s correlation was highly significant across genotypes (Pearson correlation −0.77, p < 0.0001).
The difference between the mean radiation-induced G2 scores for 0.05 Gy compared to 0.5 Gy in this cohort were highly significant (two-tailed p value < 0.0001) by the Mann–Whitney test and this is also illustrated in Figure 1 for both doses in the healthy control donors.
Here, the baseline model demonstrated the expected strong association between internal data redundancy and model performance, with a substantial and highly significant ( p < 0.0001, bootstrap test with 10,000 replications) drop in performance as the partitioning threshold is decreased (from an AUC value of 0.67 at 99% to 0.63 at 90%)—resulting in a lower similarity between the training and test data sets.
qPCR validation of a set of selected targets showed a highly significant correlation with the relative expression levels determined by RNA sequencing (Pearson R = 0.8955; P < 0.0001; Supplementary Figure S9 A).
These three trend indicators were still highly significant ( p < .0001) when added jointly to the existing model using the following transformations: X 3 + X 3 *log(X) for the absolute change in the risk score from the previous day; X 0.5 + X 0.5 *log(X) for the absolute change in the risk score from the start of the trend; and X -2 + X -2 *log(X) for the number of consecutive days with a trend in the risk score (we first shifted all original values up by the minimum observed value to ensure the values were greater than zero).
The McNemar test for correlated proportions was highly significant (p < 0.0001), indicating that the hrHPV mRNA proportions are not comparable, although this differed between age groups.
Correlation between LCD and genetic affinity were highly significant for a period of 5950–15,950 BP (r = − 0.909, p < 0.0001).
We confirmed previous findings by showing highly significant differences in rates of neurological and gastrointestinal symptoms ( p < 0.0001).
While we do not detect significant accumulation of mutations over the sampling period in this clade, both the global phylogeny and a subset sample of 1220 B.1.1 genomes including this clade exhibit a highly significant temporal signal following randomizations of sampling date ( P <1×10 −4 ) (Figs S11 and S12).
This was confirmed by comparing the intersample dissimilarities between samples, which were larger for the data sets from acidified soil and were highly significant ( P ≤ 0.0001) (see Fig.
Preexisting hypertension, diabetes mellitus, coronary artery disease, chronic kidney disease and malignancy were all highly significant risk factors for 30-day hospital admission following initial ED discharge ( p < 0.0001).
The P for trend remained highly significant across all models ( p < 0.0001).
To statistically assess the overlap between the two gene sets, we performed a Fisher’s Exact test, which demonstrated a highly significant concordance (P < 0.0001, two-sided), indicating that the shared transcriptional response is unlikely to occur by chance (Supplementary Table S1 ).
The difference of frequencies of hepatic SOS in 6-TG-containing elements compared to other treatment elements was highly significant ( P ≤ 0.0001).
By modulating ATP levels through the addition of arsenate, we show that there is indeed a highly significant correlation ( P < 0.0001) between cellular ATP levels and the development of both IbpA and Ph aggregates at the population level ( Fig. 5D and E ), as was also reported previously ( 14 ).
, 2019 ), the correlation between hangover frequency and severity was highly significant ( r = 0.710, P < 0.0001), suggesting reverse tolerance.