“highly significant”

In contrast, measurements of the relative GCR frequency within SiRTA 9L-44 are more reproducible between experiments and the difference between the RAD51 and rad51Δ strains is highly significant (p<0.0001; Fig 1E ).

Three days following sepsis the two models had an inverse correlation that was highly significant (p<0.0001) with an r = −0.284 ( Figure 4C ).

The results showed a highly significant relationship ( P < 0.0001) with C max on Day 1 with an odds ratio of 1.510 (95% CI: 1.279–1.802).

Using the comparison of the resulting log-likelihood values from running the model with and without the tree to estimate significance, both replicates produced highly significant (p<0.0001) heritability estimates of 5.8% (CI 2.9–8.7%) and 5.6% (CI 2.6–8.5%; Table 2 ).

The most remarkable finding was a highly significant lower in-hospital mortality (56.8 vs. 88.1 %, p < 0.0001) in MET users despite a more explicit risk profile (diabetes, older age) and greater baseline disease severity (higher incidences of cardiovascular disease, acute kidney injury, and underlying malignancy) [ 1 ].

Most differentially methylated probes had an intermediate methylation level in IDH WT AML patients which was increased by approximately 20% in mIDH patients and this increase was highly significant ( Fig. 1D ; P <0.0001).

Using the same background subtraction procedure, a lifetime of 2.5 ± 0.03 ns was obtained for EGFR–eGFP in the presence of EGF and Grb2–mRFP. A Student’s t test revealed that the difference in apparent lifetimes (2.85 vs 2.50 ns) was highly significant ( p < 0.0001, standard error about the mean 0.03 ns, sample size = 50).

Strikingly, the activity in lymphoblasts showed a highly significant positive correlation with levels of DHRSX protein in this cell line (see Figure 1 J) (NADH: R 2 = 0.9667; p < 0.0001, NADPH: R 2 = 0.9910; p < 0.0001; Figure 3 E).

This difference was highly significant (Χ 2 = 16.9, df = 1, p<0.0001).

Examining all products, there was a highly significant ( p < 0.0001) reduction in the median total sugar contents in 2019 compared to those in 2016: median (interquartile range): 10.4 g/100 g (6.6, 13.0) versus 11.9 g/100 (8.8, 13.6).

This result was found to be highly significant [ F ( 1 , 29 ) = 40 . 442 , p < 0 . 0001 , η 2 = 0 . 5824 ].

The onset of TAO within 2 years after the treatment with RAI and the titer of TSHR-Abs The relation between the onset of orbitopathy symptoms in patients with GD during a two-year of follow-up after a therapeutic dose of 131 I and the titer of TSHR-Abs in the serum was highly significant ( P <0.0001).

The results depicted in Figure 3 - for the TBRs, mf prevalence breakpoints and R 0 - show not only that a wide distribution of values is consistent with the data in each study community when the model is fitted to mf age prevalence but also that they can vary significantly between the study communities [kruskal-wallis tests of differences in estimated values of each variable indicating highly significant study effects in each case ( P < 0.0001 in each case)].

That approach resulted in similar results as in the linear models described above, with highly significant associations between low BDE-47 concentrations and the genotypes with MAF in the 0.36-0.45 range (all p = 10 -4 to 10 -6 )(data not shown).

Again using FP C max as an example metric, the estimated between‐batch variance (0.0598) was 1.7‐fold larger than the estimated residual variance (0.0353) and was a highly significant contributor to total variability ( P < 0.0001).

This difference in the distribution of unique peptides derived from the structural (P1) versus nonstructural (P2P3) segments of the polyprotein in the anti-HSP90 pulldown product versus the cell lysate was highly significant ( P < 0.0001) ( Fig. 4D ).

The difference in PFS-rates between group 1 and group 2 was highly significant in the Log-Rank Test (p < 0.0001).

All effects and interactions were highly significant ( P < 0.0001, F -test; n = 10,612 in total).

Irradiated samples treated with 5-ALA of 50 or 100 μg/ml showed highly significant ( p < 0.0001) reductions in cell viability compared to the irradiated 5-ALA-free controls, decreasing progressively with increasing light doses from 0 to 32 J/cm 2 .

All these differences were highly significant (pairwise two-tailed t-tests, P<0.0001).

The effect of the factor ‘year’ was highly significant ( P < 0.0001).

The impaired ability of the Exon 12 −/− mice to run on the rotorod at greater than moderate speeds is the most obvious and highly significant phenotype of the behavioral testing ( P < 0.0001).

There was a highly significant correlation between the hypoxia gene expression score and fetal blood lactate concentrations at delivery (Figure 4 ; r = 0.81, P <0.0001).

The ANOSIM yielded a highly significant difference in the chemical patterns of the two groups ( ANOSIM : r = 0.9, p = 0.0001).

Not surprisingly, in the Cox-binomial model with no other covariate this difference is highly significant (p-value < 0.0001).