“highly significant”

The increase in correlation coefficient is highly significant ( p -value < 10 -29 ) (Materials and Methods), arguing that our non-linear correction to the whole proteome abundances has increased the accuracy of these estimates.

The correlation was highly significant ( ρ = 0.7304, p < 10 −29 ) and within this set the outliers (points which depart from the diagonal) were pairs of words relating apple to other concepts: apple-orange, apple-green, and apple-salad, which are more similar in Spanish than in English.

We found a highly significant correlation between the Magenta module eigengene (based on 76 probes) and strain status ( r = 0.99, p < 1.0e-29).

Compared with the control group, combined dcEF + RL stimulation produced a highly significant increase in neurite length ( P = 2.1 × 10−29, η 2 = 0.54).

Moreover, the sample distributions in the X-axis and Y-axis show highly significant differences (Wilcoxon’s test P -value = 4.1 × 10 -29 ).

The association between the two classifications was found to be highly significant (χ 2 = 138.3, p = 6.4 × 10 −29 ).

In two-way (genotype and environment) ANOVA, the genotypic variations for the four index traits were highly significant ( P -value = 8.57e-29 ~ 3.62e-11) (Table S3 ), indicating the feasibility of conducting GWAS for the four index traits.

The resulting Manhattan plot ( Figure 5B ) identified several highly significant metabolic hubs: 3.6.1 Stress-induced lipid amide accumulation The tentative lipid amide (m/z 338.33) was the most significant feature ( p < 10 -28 ), showing prominent accumulation in T3 and T4 samples as a marker for biotic stress. 3.6.2 Phenolic partitioning and correlation with lipid derivatives Quantitative analysis showed that Benzoic acid (GC_BA-TMS) levels were significantly higher in T2 compared to all other treatments.

Pathways showing highly significant results include the MAPK signalling pathway ( p -value = 1.29E-28), the FoxO signalling pathway ( p -value = 8.09E-19), the HIF-1 signalling pathway ( p -value = 9.65E-19), the PI3K-Akt signalling pathway ( p -value = 1.09E-18), and the insulin signalling pathway ( p -value = 2.87E-16).

The rs334 SNP, when directly genotyped, was highly significant ( P = 1.3 × 10 −28 ), whilst the best marker in the GWAS SNPs ( P = 3.9 × 10 −7 ) did not reach genome-wide significance.

8 , 9 The strongest and most highly significant associations have been reported with early-onset, persistent eczema 10 , 11 (odds ratio 5·6, 95% confidence interval 4·1–7·8, P = 1·3 × 10 −28 ) and asthma occurring in individuals with atopic eczema 12 – 14 (odds ratio 3·49, 95% confidence interval 2·00–6·08, P = 1·0 × 10 −5 ).

Comparison of Models 1 ( α = β 1 = β 2 = 0) and 2 ( α = 0) in Table 2 reveals a highly significant offspring SE allelic effect on RA risk ( χ 2 2 = 128.1, p = 1.5 × 10 -28 ).

The scores only explained 3% of the variance in schizophrenia case-control status, but the large sample sizes ensured that this was highly significant (up to P = 2 × 10 −28 ).

Instead, we observe that an increase in STAT3 binding is correlated with an increase in expression in most of these pairs (83%, n = 686), an association that is highly significant at P = 2.3 × 10 −28 ( Table 4 ).

The type of incubation fluid exhibits a highly significant impact on the sorption ability, as indicated by an exceptionally low p -value ( p = 2.45 × 10 −28 ), suggesting that the fluid type strongly influences the swelling behavior of hydrogels.

However, although the difference in terms of percent variation explained in RBC by SSCCA vs SSMCCA methylomics CV1 is highly significant (p-value = 3E-28), the absolute difference (4.27E-8 percent variance explained) is tiny, suggesting the difference between the performance of two methods is negligible.

As shown in Table 2 , the DEGs from the Rat in vitro model (Rat-DEGs) exhibited a high correlation with those from the Human in vitro model (Human-DEGs), sharing a highly significant gene overlap ( P = 4.02E-28).

rs13038305 in Relation to Cystatin C At baseline each copy of the major allele of rs13038305 was associated with a highly significant approximately 0.30 standard deviation (SD) higher plasma concentration of cystatin C both in model 1 (β = 0.33, p = 4.2E-28) and model 2 (β = 0.33, p = 1.7E-29).

Although the MHC association is highly significant in both OLP and non-OLP, it is dramatically stronger in non-OLP ( p = 5.6 × 10 −28 for difference in effect), and the association in non-OLP near CLEC16A does not even reach nominal significance in OLP.

Expectedly, a highly significant naming deficit became obvious for LIP in comparison to HIP (p=7.0×10 -28 ) and healthy controls (p=9.1×10 -29 ) (Figure 2 C).

The results with GENECONV (Table 1 ) were highly significant (p values < 10 -27 -10 -66 ) between the paralogues of the same species in groups 1, 2 and 3 providing evidence of gene conversion between ancestral sequences of paralogues.

The top five ranked interlinked pathways (Supporting Information Table S5 ) and the three Gene ontology (GO) molecular function terms (Supporting Information Table S6 ) are highly significant ( p ≤10 −27 ) with respect to genes differentially expressed after RPL19 knockdown.

Inception-v4 consistently ranked last, with an accuracy of 87.42% and an AUC of 94.24%, and exhibited highly significant disadvantages compared with all other models ( p < 10 − 27).

The overlap between our gene list and previously published data [ 29 ] was highly significant (35% overlap, hyper-geometric test p < 10 −27 ), and dissimilarities were likely due to the different ages of flies in the two studies (40 days in the current study as opposed to 10 days in [ 29 ]) as previously reported [ 30 ].

However, only the primary angiosarcoma specimen, AS1, exhibited a prominent and highly significant ( P <10 −27 ) expression transition ( Figure 2A ), with the predicted breakpoint corresponding to known rearrangements of ROS1 in other malignancies.