“highly significant”

ANOVA showed that both season (i.e., autumn and spring) and population had a highly significant effect on mass-specific energy content of lipid and glycogen stores ( P << 0.0001; Table S2 ).

The difference is highly significant (t(11) = 8.5, p = 0.0001).

The χ 2 test was highly significant for all three pathologists when compared with AFMR scores (p<0.0001) as was the test for a linear-by-linear association (p<0.0001).

The cross correlation between total 25(OH)D and DBP was also highly significant (r 0.84–0.92; all P < 0.0001) but the lag times were less consistent, varying between 0 and 3 h, compared to cross correlation between DBP and total 1,25(OH) 2 D.

The non-parametric Spearman correlation test confirmed a highly significant negative correlation between 25-OH-vitamin D3 and CTX, regardless of the age (r = −0.2295, p <0.0001) ( Fig. 2 A).

IgG-S(RBD) were detectable after the first vaccine dose in 49/50 (98%) naïve recipients but with very low titers that were boosted by the second vaccine dose resulting in a highly significant increase ( p < 0.0001) (Fig. 1d and Table 2 ).

The reduction in mean plaque scores was also highly significant ( P < 0.0001).

The association between the derived APS and CCCS was also highly significant ( P < 0.0001) with a Pearson correlation coefficient of 0.3.

Therefore, differences between the CG and the IG were highly significant in both the first and second 6-month follow-up period ( p < 0.0001).

A highly significant correlation was observed between nuclear matrix protein level and 8-OHdG, highest in SA for BLCA-4 ( R = 0.583, p = 0.0001) ( Table 6 ).

The impact of HIF-1α on OS still retains highly significant (P<0.0001).

The level of significance was set at p=0.05 (p<0.05-significant, p<0.01-highly significant, p<0.0001-very highly significant).

According to an exact binomial test, the difference is highly significant ( P < 0.0001).

We found a highly significant correlation (P < 0.0001) between low or absent IPO11 and low or absent PTEN protein levels ( Fig. 7 A ).

Conversely, as found for bottlenose dolphins ( Williams et al., 2017b ), there were highly significant relationships between V̇ O 2 ss (J kg −1 min −1 ) and f S (strokes min −1 ) ( n =30 swims, d.f.=1, 28, F =25.53, P <0.0001, AICc=304.28, BIC=308.29; Fig. 4A ) for beluga whales, where: (1) and between V̇ O 2 ss (J kg −1 min −1 ) and swim speed ( U swim , m s −1 ) ( n= 30 swims, d.f.=1, 28, F =54.93, P <0.0001, AICc=288.48, BIC=291.76; Fig. 4B ), where: (2) even within the relatively narrow range of exercise efforts representing the preferred performance levels of the individual whales.

However, due to the extensive variance in fingertip force between the participants across all 13 stimuli, the explained variance was small while still highly significant ( R2 = .062, F (1,257) = 8.49; p < .0001).

Obtaining a tumor-free surgical margin decreases the incidence of a local recurrence (LR) of the primary tumor.[ 18 ] There are various risk factors associated with a positive margin, among them are: The extent of excision, age, large tumor size, multifocality, lobular histological type, and the number of positive lymph nodes.[ 19 ] In 30 of 34 reviewed studies, persistent microscopic inadequate (R1) or macroscopic inadequate (R2) surgical margins were highly significant for LR compared to the negative margin (p = 0.0001).[ 20 ] Microscopic disease resulting from a positive margin is more problematic because theoretically, cancer in the relatively hypoxic environment of the lumpectomy scar bed will be resistant to radiation therapy.[ 21 ] Furthermore, the inability to achieve negative margins may be a marker of an excessive tumor burden in the treated breast.

In the study provided in European countries, it was stated that there was a highly significant difference of 25(OH)D levels across European countries ( p < 0.0001) among women in the postmenopausal period.

The level of significance ( p -value) for each test is indicated in the figures using the following notation: ns ( p > 0.05)—non-significant, * (0.01 < p ≤ 0.05)—significant, ** (0.001 < p ≤ 0.01)—very significant, *** (0.0001 < p ≤ 0.001)—highly significant, and **** ( p ≤ 0.0001)—extremely significant. 5.

Evaluating the results by applying repeated measures of variance demonstrated a highly significant difference in individual change between the two groups ( p < 0.0001) ( Figure 2 b).

59 Bostanci et al found a significant improvement in both the psychosocial and physical measures postoperatively and highly significant effect on the overall QoL (all p<0.0001). 54 A smaller cohort study looking more specifically at body image perception found a significant improvement postoperatively. 55 Kim et al also observed a positive impact on patients’ QoL and found this to be evident early post-operatively and persistent lo

The t-test revealed that no significant differences in HI were observed within lines in NIL15-YXZ or NIL15-SBSM ( p > 0.05), but highly significant difference in mean HI was observed between NIL15-YXZ and NIL15-SBSM ( p < 0.0001).

Using the OPSCC TCGA cohort we demonstrated that HPV-associated tumors abundantly overexpress CDKN2A RNA with an average of 34-fold elevation ( Supplementary Table 6 in S1 Table s) that is highly significant (p < 0.0001, S7 Fig B ).

5 ; Table 5 revealed a highly significant ( p < 0.0001) intra-nucleosomal DNA fragmentation in hepatocytes of the ACR group, evidenced by high smear in the DNA band and low OD value at 260 nm, compared to the control and treated groups.

This difference between cDNA and gDNA is highly significant for each replicate: (Family 1: ANOVA, F 1,6 = 443.36, p<0.0001; Family 2: F 1,6 = 39.60, p = 0.0007; Family 3: F 1,6 = 219.02, p<0.0001).