“highly significant”

The results showed that compared to the blank group, the relative expressions of IL-6 , IL-8 , and TNF-α gene display a highly significant increase ( p < 0.0001) in PRRSV-infected group; and compared to PRRSV-infected group, the relative expressions of IL-6 , IL-8 , and TNF-α gene show a significantly downward trend ( p < 0.01, p < 0.001, p < 0.0001) in 12.5, 50 and 100 μmol·L −1 zinc sulfate treated groups ( Figures 7A – C ) and appeared a dose-effect relationship between the relative expressions of gene and the concentration of zinc sulfate.

The cross correlation between total 25(OH)D and DBP was also highly significant (r 0.84–0.92; all P < 0.0001) but the lag times were less consistent, varying between 0 and 3 h, compared to cross correlation between DBP and total 1,25(OH) 2 D.

The liposome-based neutralization test results correlated excellently and were highly significant with those of the pVNT ( Table S6 ), for both overall comparison (Spearman R = 0.86, p < 0.0001) as well as variant-specific comparison (all R > 0.9, all p < 0.00024) ( Figure ).

The ANOVA analysis ( Figure 3 ) showed a highly significant change from the initial level of the NRS score to all follow up values ( p < 0.0001), demonstrating that the goal of reducing pain was achieved with statistical significance during follow-up.

In NC, correlations between colour and greyscale items were highly significant ( r = .94, P < .0001), as they were for both groups of patients: AD-1: r = .93, P < .0001, and AD-2: r = .93, P < .0001.

Mortality analysis ( Figure 2 ) Kaplan-Meier analysis showed a significantly lower all-cause mortality in the HIF group compared to the ESA group, with a highly significant log-rank test ( p < 0.0001), indicating improved survival among HIF users.

Analysis with ANOVA indicated a highly significant difference in parasitic numbers between any of the treated groups and the control group (F = 158.81; P = 0.0001).

Survival curve analysis revealed highly significant differences between these groups in the training set (p < 0.0001) ( Figure 4E ).

The random effects for feed and COM, the zero inflation parameter, and the square root concentration effect were all highly significant (p<0.0001).

Fear of parental accident modelisation and car accidents death rate The ecological variable, car accident death rate per 100,000 population, was highly significant and indicated that higher rates were associated with increased odds of reporting fear of a parent’s accident (p<0.0001).

Likewise, there was also a highly significant difference between umbilical hernia and epigastric hernia ( p < 0.0001).

S1 , Supplementary Material online), differences with PALO being highly significant for Mammalia, Vertebrata, and paralogs (Mann–Whitney test P < 10 −4 ).

The quadratic equation generated from the models ( Figure 2 ) is the following Equation (2): (2) Rupture strength = −71.72 + 19.14A + 15.99B + 3381.93C + 4.78D − 0.43AB + 136.21AC − 0.29AD − 460.12BC + 0.88BD − 79.31CD − 4.30A2 − 32560.72C2 − 0.22D2 − 3.43B2 The compressive strength response surface model was highly significant (F = 22.36, p < 0.0001, Table S3 ), accounting for 91.16% of the total variation ( R 2 = 0.9116, adjusted R 2 = 0.9116, predicted R 2 = 0.834) with a non-significant lack-of-fit ( p = 0.683), confirming the model reliability.

Figure 3 shows that the reduction of bacterial load by vancomycin at the sub-inhibitory concentration (16 μg/mL) in all the combinations was statistically highly significant ( P < 0.0001) in the planktonic stage.

A highly significant difference was observed between the mean of IgG1:2a ratio in resistant and susceptible mice (Mann Whitney U test, p < 0.0001, Figure 1 B).

A large and highly significant difference in EBNA-1 IgM/IgG/IgA levels between RA patients and HCs and between RA patients and SLE patients ( P < 0.0001 for all 3 antibody isotypes) was observed.

The regression analysis for DPPH IC50 response, the individual component coefficients (β1,β2, β3), and the ternary interaction term (β123) were all highly significant (p < 0.0001), showing individual oil effects and their combination effects in a significant manner on DPPH radical scavenging activity.

Additionally, air temperature, rainfall, relative humidity, study location and animal identifier were all highly significant (P < 0.0001) (Table 5 ).

In a separate model of the group of secondary auditory sites, in contrast, these factors are highly significant ( t = 7.17; p< 0.0001, and t = 3.89; p = 0.0002, respectively), showing that in secondary auditory areas such modulation is call-specific.

This was confirmed by a hierarchic (nested) analysis of variance (ANOVA), which showed highly significant among-cell (subgroup) variability regardless of the parameter tested (P < 0.0001, peak amplitude, risetime, halfwidth, and foot duration were tested after logarithmic transformation, cubic-root of the charge was tested without transformation).

A quadratic regression model (Equation (4)) was developed to relate the response variable to the independent factors. (4) Y = 67.75 + 0.96 A + 2.43 B − 0.34 C + 1.32 AB − 0.20 AC + 1.38 BC − 0.80 A 2 − 3.68 B 2 − 0.25 C 2 The developed model was highly significant ( p < 0.0001, Table 4 ).

np is the number of parameters in the model; lnL is the log likelihood score; AIC (Akaike Information criterion = −2*lnL+2*np) is a measure of the goodness of fit of an estimated statistical model; ω is the nonsynonymous/synonymous substitution ratio; LR is the likelihood ratio: df is the degree of freedom in LRT (Likelihood Ratio Test); *** Highly significant (p-value<0.0001).

This demonstrated that the lipolysis/plasma lipid relationships were still highly significant ( P <0.0001) after correction for sex; age; body mass index; waist circumference; waist-to-hip ratio; nicotine use; treatment of type 2 diabetes mellitus, hypertension, or hyperlipidemia; and fat cell size.

The measured 2.4–2.6% CO 2 concentration translates into a highly significant increase in CO 2 with a KN95 respirator and a valved respirator at the nasolabial fold (p < 0.0001), which is much greater than the NIOSH 8h threshold limit value [ 57 ].

impatiens was highly significant ( p < 0.0001; FET).