“highly significant”

This difference remained highly significant after formal statistical comparison (Mann–Whitney U test, p < 0.0001) ( Figure 7 ).

H-FABP showed 76.92% sensitivity, 100% specificity, and a highly significant P < 0.0001 within the 3-h window, while Trop-T’s sensitivity improved over time from 35.90% at presentation to 84.60% at 6–12 h.

We further plotted the MAGEA3 protein score versus the DUB3 protein score for individual HCC patients, which revealed a highly significant correlation (linear regression R 2 = 0.63, p < 1 × 10 −4 ; Figure 3 H).

Conversely, the treatment caused a highly significant ( p < 0.0001) decrease in Pol, Tax, and HBZ expression with respect to the untreated control in PB2/NO-IL-2 cells.

Females with low HDL (61.02%, n=72) were in a larger proportion compared to males (38.98%, n=46), and this difference was highly significant (p<0.0001) (Table 2 ).

The second-order model obtained in terms of coded variables for extraction efficiency ( E (%)) of BB seed oil using UAE is given by Equation (1): (1) E % = 80.74 + 9.375 X 1 − 2.495 X 1 2 + 2.875 X 2 − 3.495 X 2 2 + 0.5 X 3 − 2.745 X 3 2 − 1.25 X 1 X 2 − X 1 X 3 + X 2 X 3 The ANOVA statistic for extraction efficiency (the response variable) proved that the regression model is highly significant, having a very high F-value of 46.67 and a low p -value of p < 0.0001.

At 30 days post-injury, B cell-treated animals showed highly significant improvement in Y maze performance (p < 0.0001), with better alternation scores as compared to saline-treated ICH controls and values similar to sham-injured controls ( Fig. 2 E).

In the ‘immediately after surgery’ subgroup, the SMD with a 95% CI is −0.76 [−1.10, −0.42], with a highly significant p -value < 0.0001, I 2 = 9%.

This perfectly matches ANOVA table, where D had the highest F-value (486.64) and was highly significant ( p < 0.0001). pH is the next major contributing factor.

Treatment with cell-free supernatant from LSSA01 resulted in a robust increase in phagocytosis, reaching 286.1 ± 28.6%, which was highly significant compared with the control ( p < 0.0001).

Substance and alcohol abuse and supplement use Association with MD and alcohol use measured by RAPI was highly significant (Table 5 ) (p < 0.0001).

Irrespective of probiotic treatment, the ME content of the diets had a highly significant ( P < 0.0001) effect on the liver weight of broilers when expressed as a percentage of BW.

In a univariate logistic regression, we observed a highly significant positive association between the composite index score and the likelihood of aflatoxin detection (OR 1.6, p < 0.0001).

The model was highly significant ( p < 0.0001), while the lack-of-fit was not significant ( p = 0.9735), and the R 2 value was 0.9323, indicating that the model had good fitting and predictive ability.

The proportion of CLas-infected (qPCR positive) leaves, following a 4-day inoculation period (with 5 insects/leaf), was 2.5% (1/40 leaves) for nymphs and 36.3% (29/80 leaves) for adults, and this difference was highly significant ( P = 0.0001 in X 2 test).

Highly significant differences were found among the treatments (χ 2 = 154.0; d.f. = 3; p < 0.0001).

In the second cohort, the association was highly significant ( r = −0.60; P < 0.0001) ( Fig. 2 B ).

All these differences were highly significant at P < 0.0001.

Among treatments, QE and QL produced the highest reduction in bait intake, particularly at higher concentrations (50 and 100 ppm), where differences were highly significant ( p < 0.0001) for both sexes.

A subgroup comparison consisting of all age- and sex-matched controls also demonstrated highly significant difference between HGPS (progerin, 34 512±14 432 pg/mL; n=25) and non-HGPS control levels (progerin, 377±226 pg/mL; n=13; P <0.0001).

Both workflows produced large, highly significant, and quantitatively comparable PC-versus-NC separation under genuine operating conditions (manual: Δ_CI = 0.096 and 0.103; Welch’s t = 19.83 and 21.95; p < 0.0001; Cohen’s d = 1.19 and 1.32; CSA risk scale Δ_P– N = 14.47 with biobank-derived urine-based materials and 10.17 with synthetic VOC standards).

The difference in MIC between the two agents against the standard isolate was highly significant ( p < 0.0001), whereas the difference in MBC was not statistically significant ( p = 0.1030).

Both AI-based and human-based evaluations demonstrated highly significant reductions in root length between pre- and post-treatment measurements ( p < 0.0001).

Peak amplitude recovery exhibited a highly significant positive correlation with increasing IBIs in all regions examined, including CA1-SR ( Figure 5D , p < 0.0001), CA2-SR ( Figure 5F , p < 0.0001), and CA1-SLM ( Figure 5H , p < 0.0001).

We observed a highly significant inverse correlation between sleep and BBB permeability ( r = −0.564, p < 0.0001; Figure 3B and Table S1 ).