Our results show that the main effects of loudness were highly significant on the head movement in Z direction [ t (98) = 5.9, p < 0.0001].
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At the local scale, analysis revealed a highly significant isolation-by-distance pattern when all areas were tested jointly (r 2 = 0.069; Mantel test p < 0.0001; Figure 5 ).
While CSF levels from control cases were largely close to LOD, the TBI group shows statistically highly significant elevated levels in CSF ( p < 0.0001, see Fig. 3b ), but no differences regarding the TBI bleeding type ( p = 0.7240; see Supplemental Table 1 ).
However, multiple regression analysis indicated that the quadratic terms (X 1 2 , X 2 2 and X 3 2 ) were highly significant ( p < 0.0001) for the extraction of TPC and is revealed in Table 3 , as for the antioxidant activity.
Altered K/Na, Ca/Na and Mg/Na Concentration Ratios Are Strong Indicators of Na-Stress Exposure The ANOVA summary for concentration ratios of K, Ca or Mg with Na in examined test crop tissues showed a highly significant ( p < 0.0001) impact of NaCl salinity, whereas the soil Cd contamination as well as the CdxNaCl interaction were not significant ( Table S3 ).
Kumar and Ganesh [ 20 ] described the analysis for WOMAC between group A and group B after 9 months as highly significant (p= 0.0001), but did not provide any further details such as means and variance.
One-way ANOVA demonstrated a highly significant effect of incubation time on biofilm formation ( p < 0.0001, R 2 = 0.966).
Based on the hypothesis that the response to radiation could associate proteins or p-sites involved in the same molecular pathway, we submitted all statistically highly significant candidates (R>0.5 or <-0,5 and P<0.0001) to STRING analysis 30 .
The overall F ST and Ф ST values both showed highly significant isolation among all populations ( F ST = 0.20, p < .0001; Ф ST = 0.74, p < .0001).
This removal did not change the non-overlapping distributions of hues between positive and negative samples and this difference in distributions in highly significant (P<0.0001).
On the treated, right (ipsi-lateral) hind paw, the CFA-treatment induced a highly significant increase in pain sensitivity on the first experimental day, MWT dropped to 2.96 ± 0.052 g ( p = 0.000101).
Expression of the NT5C2 allele in phase with the ch10_104957618_I risk allele was also reduced in all assayed adult brain regions (mean DLPFC: 15%, hippocampus: 12%, caudate: 13%), with highly significant differences in allele ratios observed between cDNA and genomic DNA that survived Bonferroni correction in all areas (DLPFC: P = 1.03 × 10 −4 , corrected P = 0.003; hippocampus: P = 2.64 × 10 −6 , corrected P = 8.46 × 10 −5 ; caudate P = 8.11 × 10 −5 , corrected P = 0.0025).
The corresponding F is highly significant (F= 7.34, df= 208, 211, p= 0.0001059), showing that the patient group differs considerably from the healthy volunteer group.
Conversely, motif analysis of the repressive H3K27me3 peaks exhibited a strikingly uniform and highly significant (Adjusted p = 0.000106) enrichment of the Helicase-like transcription factor (HLTF) motif, which was present in over 85% of the target sequences ( Supplementary Figure 3B ).
These differences were highly significant when considering qPCR results of PMA vs. non-PMA samples in a paired t test ( p = 0.000106).
The association analysis of ARDS and COVID-19 fatality rates showed a highly significant value ( p value = 0.000106022666010979).
Upon exploring protein-protein interactions between the 92 DE ExclusiveMS genes using STRING, a highly significant enrichment for PPI was identified ( P = 1.07 × 10 −4 ; Figure S2 ), indicating that these genes act together or respond in concert to detrimental mechanical stress.
0 controls), but the association signal remained highly significant, with a much higher odds ratio (OR = 27.68 [95% CI 1.5–528.7], P = 1.08 × 10 −4 ) (Table 3 ).
Thus, the hot-spot mutations in SARS-CoV-2 were enriched within IRs loci and this association was highly significant statistically ( P -value = 0.0001085; t = −5.94, df = 9, one-sample t -test) ( Figure 1 ).
Regression analysis for the observable t h and independent variable t policy1 yields a highly significant linear correlation (p-value = 1.09 ⋅ 10 −4 ).
Only the Rh5 SNPs 439 and 442 were highly significant, p = 0.00011 (see Additional file 5 ) and remained significant after a Bonferroni correction.
The difference in distribution of AKT-sensitive and AKT-insensitive drugs to the M area was statistically highly significant (Fisher exact test: p = 0.00011).As expected, the group of AKT-insensitive drugs mapping to the M region included typical microtubuli-targeting drugs such as colchicine, vinblastine, and podophyllotoxin.
Meta-analysis was highly significant (−482T meta-analysis p = 1.1 × 10 -4 ).
TG to HDL cholesterol ratio was also a strong and highly significant predictor (β = –9.9, P = 1.1 × 10 –4 ) (model 2), although this relation was attenuated with inclusion of current BMI (model 3).
Of the 22 genes in the immediate neighborhood of ApoE , including ApoE itself, 4 (18.2%) were inferred as differentially connected between the wild type and ApoE −/− crosses, and this proportion was highly significant (∼8.1 fold enrichment, FET p -value<1.1×10 −4 , permutation adjusted p -value<0.001) ( Figure 5 and Figure S5C ).